Income Taxes - Reconciliation Between Effective Tax Rate and Statutory Income Tax Rate (Detail)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Income Tax Disclosure [Abstract]
Federal income tax rate	21.00%	21.00%	21.00%
State taxes	(0.50%)	(7.70%)	4.10%
Research and development tax credits	(8.30%)	28.30%	6.90%
Valuation allowance	2.20%	(13.70%)	(14.70%)
Permanent differences	0.10%	(0.20%)	(1.10%)
Stock-based compensation	6.10%	(2.00%)	(1.50%)
Excess benefit stock deductions	(4.30%)	1.60%	0.30%
Foreign rate differential	(7.20%)	(11.30%)	(13.20%)
Non-deductible repurchase premium	0.00%	0.00%	(2.20%)
Non-deductible premium on note conversion	0.00%	(15.30%)	0.00%
Other	0.70%	(3.80%)	(1.60%)
Effective tax rate	9.80%	(3.10%)	(2.00%)