Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Other Comprehensive Gain (Loss) [Member]	Accumulated Deficit [Member]
Balance at Dec. 31, 2021	$ 928,009	$ 9	$ 4,134,768	$ (20)	$ (3,206,748)
Balance (in shares) at Dec. 31, 2021		87,127
Exercise of options for common stock	22,573		22,573
Exercise of options for common stock, shares		318
Vest of restricted stock units/awards		389
Issuance of common stock under employee stock purchase plan	7,470		7,470
Issuance of common stock under employee stock purchase plan, shares		116
Stock-based compensation	233,018		233,018
Purchase of capped call share options for 2027 Notes	(127,305)		(127,305)
Settlement of capped call share options for 2024 Notes	26,317		26,317
Unrealized losses from available-for-sale securities, net of tax	(1,644)			(1,644)
Net Income (Loss)	(703,488)				(703,488)
Balance at Dec. 31, 2022	384,950	$ 9	4,296,841	(1,664)	(3,910,236)
Balance (in shares) at Dec. 31, 2022		87,950
Exercise of options for common stock	40,485		40,485
Exercise of options for common stock, shares		528
Vest of restricted stock units/awards		645
Issuance of common stock for exchange of 2024 Notes, shares		4,456
Issuance of common stock for exchange of 2024 Notes, value	693,377		693,377
Issuance of common stock under employee stock purchase plan	10,761		10,761
Issuance of common stock under employee stock purchase plan, shares		153
Stock-based compensation	182,514		182,514
Purchase of capped call share options for 2027 Notes	0
Settlement of capped call share options for 2024 Notes	80,645		80,645
Unrealized losses from available-for-sale securities, net of tax	2,582			2,582
Net Income (Loss)	(535,977)				(535,977)
Balance at Dec. 31, 2023	859,337	$ 9	5,304,623	918	(4,446,213)
Balance (in shares) at Dec. 31, 2023		93,732
Exercise of options for common stock	$ 67,320	$ 1	67,319
Exercise of options for common stock, shares	850,117	850
Vest of restricted stock units/awards	734
Issuance of common stock for exchange of 2024 Notes, shares		1,441
Issuance of common stock for exchange of 2024 Notes, value	$ 105,757		105,757
Issuance of common stock under employee stock purchase plan	12,205		12,205
Issuance of common stock under employee stock purchase plan, shares		143
Stock-based compensation	205,133		205,133
Purchase of capped call share options for 2027 Notes	0
Unrealized losses from available-for-sale securities, net of tax	(1,136)			(1,136)
Modification of 2017 Capped Calls	43,887		43,887
Net Income (Loss)	235,239				235,239
Balance at Dec. 31, 2024	$ 1,527,742	$ 10	$ 5,738,924	$ (218)	$ (4,210,974)
Balance (in shares) at Dec. 31, 2024		96,900