Income Taxes - Analysis of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Deferred tax assets:
Net operating loss carryforwards	$ 67,594	$ 154,948
Difference in depreciation and amortization	35,805	36,611
Research and development tax credits	381,451	374,017
Stock-based compensation	107,775	94,452
Lease liabilities	48,172	33,792
Capitalized inventory	7,009	35,269
Debt discount	18,678	25,597
Capitalized research and development costs	203,416	106,534
Other	52,658	50,308
Total deferred tax assets	922,558	911,528
Deferred tax liabilities:
Right of use asset	(31,971)	(25,800)
Debt discount	0	0
Total deferred tax liabilities	(31,971)	(25,800)
Valuation allowance	(888,335)	(883,665)
Net deferred tax assets	$ 2,252	$ 2,063