0001140361-14-031051.txt : 20140806 0001140361-14-031051.hdr.sgml : 20140806 20140806161545 ACCESSION NUMBER: 0001140361-14-031051 CONFORMED SUBMISSION TYPE: 10-Q PUBLIC DOCUMENT COUNT: 13 CONFORMED PERIOD OF REPORT: 20140630 FILED AS OF DATE: 20140806 DATE AS OF CHANGE: 20140806 FILER: COMPANY DATA: COMPANY CONFORMED NAME: DELCATH SYSTEMS, INC. CENTRAL INDEX KEY: 0000872912 STANDARD INDUSTRIAL CLASSIFICATION: SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841] IRS NUMBER: 061245881 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 10-Q SEC ACT: 1934 Act SEC FILE NUMBER: 001-16133 FILM NUMBER: 141020159 BUSINESS ADDRESS: STREET 1: 810 SEVENTH AVENUE STREET 2: 35TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10019 BUSINESS PHONE: (212) 489-2100 MAIL ADDRESS: STREET 1: 810 SEVENTH AVENUE STREET 2: 35TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10019 FORMER COMPANY: FORMER CONFORMED NAME: DELCATH SYSTEMS INC DATE OF NAME CHANGE: 19990607 10-Q 1 form10q.htm DELCATH SYSTEMS INC 10-Q 6-30-2014

UNITEDSTATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM 10-Q

x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended June 30, 2014
or

o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from ____________ to ____________

Commission File Number:  001-16133

DELCATH SYSTEMS, INC.
(Exact name of registrant as specified in its charter)

Delaware
 
06-1245881
(State or other jurisdiction of incorporation or organization)
 
(I.R.S. Employer Identification No.)

810 Seventh Avenue, 35th Floor New York, NY 10019
(Address of principal executive offices)

(212) 489-2100
(Registrant’s telephone number, including area code)

Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.
Yes x  No o
 
Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).
Yes x  No o
 
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company.  See definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer  o
Accelerated filer
o
Non-accelerated filer    x    (Do not check if a smaller reporting company)
Smaller reporting company  
o

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).
Yes o  No x
As of August 4, 2014, 9,451,930 shares of the Company’s common stock, $0.01 par value, were outstanding.

DELCATH SYSTEMS, INC.
Table of Contents
 
PART I—FINANCIAL INFORMATION
Page
 
 
 
 
Item 1.
Financial Statements (Unaudited)
 
 
 
2
 
 
3
 
 
4
 
 
5
Item 2.
14
Item 3.
27
Item 4.
28
 
 
 
PART II—OTHER INFORMATION
 
 
 
 
Item 1.
29
Item 1A. 
31
Item 2.
31
Item 3.
31
Item 4.
31
Item 5.
31
Item 6.
32
 
 
 
33
DELCATH SYSTEMS, INC.
Condensed Consolidated Balance Sheets
(Unaudited)
(in thousands, except share data)
 
 
 
June 30,
2014
   
December 31,
2013
 
ASSETS
 
   
 
Current assets
 
   
 
Cash and cash equivalents
 
$
27,284
   
$
31,249
 
Accounts receivables, net
   
172
     
349
 
Inventories, net
   
600
     
719
 
Prepaid expenses and other current assets
   
852
     
1,711
 
Total current assets
   
28,908
     
34,028
 
Property, plant and equipment, net
   
2,421
     
3,069
 
Total assets
 
$
31,329
   
$
37,097
 
 
               
LIABILITIES AND STOCKHOLDERS’ EQUITY
               
Current liabilities
               
Accounts payable
 
$
239
   
$
582
 
Accrued expenses
   
4,087
     
3,740
 
Warrant liability
   
1,075
     
2,310
 
Total current liabilities
   
5,401
     
6,632
 
Other non-current liabilities
   
748
     
366
 
Total liabilities
   
6,149
     
6,998
 
 
               
Commitments and contingencies (Note 11)
   
     
 
 
               
Stockholders’ equity
               
Preferred stock, $.01 par value; 10,000,000 shares authorized; no shares issued  and outstanding at June 30, 2014 and December 31, 2013
   
     
 
Common stock, $.01 par value; 170,000,000 shares authorized; 9,451,870 and 8,394,397 shares issued and 9,447,392 and 8,392,641 shares outstanding at June 30, 2014 and December 31, 2013, respectively *
   
95
     
84
 
Additional paid-in capital
   
264,072
     
259,102
 
Accumulated deficit
   
(239,010
)
   
(229,132
)
Treasury stock, at cost; 1,757 shares at June 30, 2014 and December 31, 2013 *
   
(51
)
   
(51
)
Accumulated other comprehensive income
   
74
     
96
 
Total stockholders’ equity
   
25,180
     
30,099
 
Total liabilities and stockholders’ equity
 
$
31,329
   
$
37,097
 

* Reflects a one-for-sixteen (1:16) reverse stock split effected on April 8, 2014.

See accompanying Notes to Condensed Consolidated Financial Statements
DELCATH SYSTEMS, INC.
Condensed Consolidated Statements of Operations and Comprehensive Loss
(Unaudited)
(in thousands, except share and per share data)
 
 
 
Three months ended
June 30,
   
Six months ended
June 30,
 
 
 
2014
   
2013
   
2014
   
2013
 
REVENUES
 
   
   
   
 
Product revenues
 
$
251
   
$
   
$
561
   
$
81
 
Other revenues
   
     
     
     
300
 
Total revenues
   
251
     
     
561
     
381
 
 
                               
COSTS OF SALES
                               
Costs of goods sold
   
(66
)
   
(332
)
   
(160
)
   
(363
)
Gross profit
   
185
     
(332
)
   
401
     
18
 
 
                               
OPERATING EXPENSES
                               
Selling, general and administrative
   
4,597
     
6,263
     
8,416
     
12,346
 
Research and development
   
1,492
     
3,992
     
2,949
     
8,462
 
Total operating expenses
   
6,089
     
10,255
     
11,365
     
20,808
 
Loss from operations
   
(5,904
)
   
(10,587
)
   
(10,964
)
   
(20,790
)
OTHER INCOME (EXPENSE)
                               
Change in fair value of warrant liability, net
   
1,297
     
5,115
     
1,092
     
2,842
 
Interest income
   
1
     
5
     
2
     
15
 
Other income (expense)
   
6
     
(15
)
   
(8
)
   
(395
)
Net loss
 
$
(4,600
)
 
$
(5,482
)
 
$
(9,878
)
 
$
(18,328
)
 
                               
LOSS PER COMMON SHARE
                               
Basic loss per common share *
 
$
(0.49
)
 
$
(0.91
)
 
$
(1.06
)
 
$
(3.22
)
Diluted loss per common share *
 
$
(0.52
)
 
$
(0.91
)
 
$
(1.08
)
 
$
(3.22
)
 
                               
WEIGHTED AVERAGE COMMON SHARES
                               
Basic weighted average common shares outstanding *
   
9,426,169
     
6,023,785
     
9,363,123
     
5,683,380
 
Diluted weighted average common shares outstanding *
   
9,480,933
     
6,023,785
     
9,462,717
     
5,683,380
 
 
                               
OTHER COMPREHENSIVE INCOME (LOSS)
                               
Foreign currency translation adjustments
 
$
(20
)
 
$
6
   
$
(22
)
 
$
369
 
Comprehensive loss
 
$
(4,620
)
 
$
(5,476
)
 
$
(9,900
)
 
$
(17,959
)

* Reflects a one-for-sixteen (1:16) reverse stock split effected on April 8, 2014.

See accompanying Notes to Condensed Consolidated Financial Statements

DELCATH SYSTEMS, INC.
Condensed Consolidated Statements of Cash Flows
(Unaudited)
(in thousands)
 
 
 
Six months ended
June 30,
 
 
 
2014
   
2013
 
Cash flows from operating activities:
 
   
 
Net loss
 
$
(9,878
)
 
$
(18,328
)
Adjustments to reconcile net loss to net cash used in operating activities:
               
Stock option compensation expense
   
257
     
571
 
Restricted stock compensation expense
   
60
     
241
 
Depreciation expense
   
499
     
604
 
Provision for inventory obsolescence
   
102
     
17
 
Warrant liability fair value adjustment
   
(1,092
)
   
(2,842
)
Loss on write-downs and disposals of equipment
   
123
     
5
 
Non-cash interest income
   
     
1
 
Changes in assets and liabilities:
               
Decrease (increase) in prepaid expenses and other current assets
   
856
     
(132
)
Decrease in accounts receivable
   
183
     
84
 
Decrease in inventories
   
15
     
157
 
Increase (decrease) in accounts payable and accrued expenses
   
7
     
(1,576
)
Increase (decrease) in other non-current liabilities
   
383
     
(300
)
Net cash used in operating activities
   
(8,485
)
   
(21,498
)
 
               
Cash flows from investing activities:
               
Purchase of property, plant and equipment
   
     
(79
)
Proceeds from sales of property, plant and equipment
   
22
     
 
Net cash provided by (used in) investing activities
   
22
     
(79
)
 
               
Cash flows from financing activities:
               
Net proceeds from sale of stock and exercise of stock options and warrants
   
4,521
     
29,975
 
Net cash provided by financing activities
   
4,521
     
29,975
 
Foreign currency effects on cash
   
(23
)
   
202
 
Net (decrease) increase in cash and cash equivalents
   
(3,965
)
   
8,600
 
 
               
Cash and cash equivalents:
               
Beginning of period
   
31,249
     
23,726
 
End of period
 
$
27,284
   
$
32,326
 
 
               
Supplemental non-cash activities:
               
Fair value of warrants exercised
 
$
143
   
$
219
 

See accompanying Notes to Condensed Consolidated Financial Statements
DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements
 
(1) General

The interim Condensed Consolidated Financial Statements of Delcath Systems, Inc. (“Delcath” or the “Company”) for the three and six months ended June 30, 2014 and 2013 should be read in conjunction with the Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K (“Annual Report”) for the year ended December 31, 2013, which has been filed with the Securities Exchange Commission (“SEC”) and can also be found on the Company’s website (www.delcath.com). In these notes the terms “us”, “we” or “our” refer to Delcath and its consolidated subsidiaries.

On April 8, 2014, the Company effected a one-for-sixteen (1:16) reverse stock split. Refer to Note 7 Stockholders’ Equity of these Condensed Consolidated Financial Statements for further information.

Description of Business

Delcath Systems, Inc. is a specialty pharmaceutical and medical device company focused on oncology. Our proprietary product—Melphalan Hydrochloride for Injection for use with the Delcath Hepatic Delivery System (Melphalan HDS)—is designed to administer high dose chemotherapy to the liver, while controlling the systemic exposure to those agents. The Company's principal focus is on the treatment of primary and metastatic liver cancers.

In the United States, Melphalan HDS is considered a combination drug and device product, and is regulated as a drug by the United States Food and Drug Administration (FDA). Melphalan HDS has not been approved for sale in the United States. In Europe, our proprietary system to deliver and filter melphalan hydrochloride is marketed as a device under the trade name Delcath Hepatic CHEMOSAT® Delivery System for Melphalan (CHEMOSAT). In April 2012, we obtained authorization to affix a CE Mark for Generation Two CHEMOSAT.  The right to affix the CE mark allows the Company to market and sell CHEMOSAT in Europe. The Company has initiated plans to investigate Melphalan HDS for primary liver cancer.

The Company has incurred losses since inception. The Company anticipates incurring additional losses until such time, if ever, that it can generate significant sales. Management believes that its capital resources are adequate to fund operations through the first half of 2015, but anticipates that additional working capital may be required to continue operations. To the extent additional capital is not available when needed, the Company may be forced to abandon some or all of its development and commercialization efforts, which would have a material adverse effect on the prospects of the business.  Operations of the Company are subject to certain risks and uncertainties, including, among others, uncertainties and risks related to product development; regulatory approvals; technology; patents and proprietary rights; comprehensive government regulations; limited commercial manufacturing; marketing and sales experience; and dependence on key personnel.

Basis of Presentation

These interim Condensed Consolidated Financial Statements are unaudited and were prepared by the Company in accordance with generally accepted accounting principles in the United States of America (GAAP) and with the SEC’s instructions to Form 10-Q and Article 10 of Regulation S-X. They include the accounts of all entities controlled by Delcath and all significant inter-company accounts and transactions have been eliminated in consolidation.
 
The preparation of interim financial statements requires management to make assumptions and estimates that impact the amounts reported. These interim Condensed Consolidated Financial Statements, in the opinion of management, reflect all adjustments, consisting of normal recurring accruals, necessary for a fair presentation of the Company’s results of operations, financial position and cash flows for the interim periods ended June 30, 2014 and 2013; however, certain information and footnote disclosures normally included in our Annual Report have been condensed or omitted as permitted by GAAP. It is important to note that the Company’s results of operations and cash flows for interim periods are not necessarily indicative of the results of operations and cash flows to be expected for a full fiscal year.

Significant Accounting Policies

A description of our significant accounting policies has been provided in Note 3 Summary of Significant Accounting Policies to the Consolidated Financial Statements included in our Annual Report.
DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements
 
Recently Adopted Accounting Pronouncements

In March 2013, the FASB issued ASU 2013-05, Foreign Currency Matters (Topic 830): Parent's Accounting for the Cumulative Translation Adjustment upon Derecognition of Certain Subsidiaries or Groups of Assets within a Foreign Entity or of an Investment in a Foreign Entity, which permits an entity to release cumulative translation adjustments into net income when a reporting entity (parent) ceases to have a controlling financial interest in a subsidiary or group of assets that is a business within a foreign entity.  Accordingly, the cumulative translation adjustment should be released into net income only if the sale or transfer results in the complete or substantially complete liquidation of the foreign entity in which the subsidiary or group of assets had resided, or, if a controlling financial interest is no longer held. The revised standard became effective for fiscal years beginning after December 15, 2013. The Company adopted this guidance effective January 1, 2014.  The Company’s adoption of this standard did not have a material impact on its consolidated financial statements.

Accounting Pronouncements Not Yet Adopted

In May 2014, the FASB issued ASU 2014-09, Revenue from Contracts with Customers (“ASU 2014-09”) that updates the principles for recognizing revenue. The core principle of the guidance is that an entity should recognize revenue to depict the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. ASU 2014-09 also amends the required disclosures of the nature, amount, timing and uncertainty of revenue and cash flows arising from contracts with customers. ASU 2014-09 is effective for annual reporting periods beginning after December 15, 2016, including interim periods within that reporting period. The Company expects to adopt this guidance when effective, and the impact on our financial statements is not currently estimable.

In June 2014, the FASB issued ASU 2014-12, Accounting for Share-Based Payments When the Terms of an Award Provide That a Performance Target Could Be Achieved after the Requisite Service Period (“ASU 2014-12”). ASU 2014-12 requires that a performance target that affects vesting and that could be achieved after the requisite service period be treated as a performance condition. As such, the performance target should not be reflected in estimating the grant-date fair value of the award. ASU 2014-12 is effective for annual reporting periods beginning after December 15, 2015, with early adoption permitted. The Company is evaluating the potential impacts of the new standard on its existing stock-based compensation plans.

(2) Inventories

Inventories consist of the following:

(in thousands)
 
June 30,
2014
   
December 31,
2013
 
Raw materials
 
$
196
   
$
249
 
Work-in-process
   
295
     
364
 
Finished goods
   
109
     
106
 
Total inventory
 
$
600
   
$
719
 
 
(3) Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consist of the following:

(in thousands)
 
June 30,
2014
   
December 31,
2013
 
Kits for clinical use
 
$
327
   
$
287
 
Insurance premiums
   
322
     
407
 
Professional fees
   
27
     
377
 
Income tax credits receivable
   
18
     
326
 
Other1
   
158
     
314
 
Total prepaid expenses and other current assets
 
$
852
   
$
1,711
 
 
1 Other consists of various prepaid expenses and other current assets with no individual item accounting for more than 5% of the total balance at June 30, 2014 and December 31, 2013.
DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements

(4) Property, Plant, and Equipment

Property, plant, and equipment consist of the following:

(in thousands)
 
June 30,
2014
   
December 31,
2013
 
Enterprise hardware and software
 
$
2,009
   
$
2,143
 
Leaseholds
   
1,667
     
1,749
 
Equipment
   
1,421
     
1,552
 
Furniture
   
957
     
957
 
Buildings and land
   
603
     
603
 
Property, plant and equipment, gross
   
6,657
     
7,004
 
Accumulated depreciation
   
(4,236
)
   
(3,935
)
Property, plant and equipment, net
 
$
2,421
   
$
3,069
 

Depreciation expense for the three and six months ended June 30, 2014 was approximately $0.3 million and $0.5 million, respectively, as compared to approximately $0.3 million and $0.6 million for the same periods in 2013.

(5) Accrued Expenses

Accrued expenses consist of the following:
 
(in thousands)
 
June 30,
2014
   
December 31,
2013
 
Compensation, excluding taxes
 
$
2,470
   
$
1,866
 
Deferred rent
   
315
     
485
 
Professional fees
   
224
     
360
 
Short-term portion of lease restructuring
   
209
     
 
Other1
   
869
     
1,029
 
Total accrued expenses
 
$
4,087
   
$
3,740
 
 
1 Other consists of various accrued expenses, with no individual item accounting for more than 5% of current liabilities at June 30, 2014 and December 31, 2013.
 
In November 2013, the Board of Directors approved an Employee Retention Program for certain key employees, including the Company’s executive officers. The key employees will be eligible to receive a cash retention bonus payment equal to fifty percent (50%) of their current annual salary if they remain employed by the Company through March 31, 2015. The expense related to this program is being accrued ratably over the required service period and has been included in Accrued expenses on the Condensed Consolidated Balance Sheets and in both Selling, general and administrative and Research and development on the Condensed Consolidated Statements of Operations.

For a description of the Company’s lease restructuring liability refer to Note 6 Restructuring Expenses of these Condensed Consolidated Financial Statements.

(6) Restructuring Expenses

During 2013, the Company implemented workforce restructurings to better focus its organizational structure, increase efficiency and concentrate financial resources on its clinical development program and European commercialization activity. This resulted in a total reduction in the Company’s workforce by 50 employees. During the second quarter of 2014, the Company implemented additional workforce restructurings that resulted in a total reduction in the Company’s workforce by seven employees. As a result of termination benefits provided to these 57 employees the Company has incurred a total restructuring charge of approximately $4.8 million for employee related expenses. At June 30, 2014, the remaining restructuring reserve of approximately $1.5 million is included in Accrued expenses and Other non-current liabilities on the Condensed Consolidated Balance Sheets for approximately $1.4 million and $0.1 million, respectively.
DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements
 
In order to more appropriately align its office space with the reduced size of its workforce, during the quarter ended June 30, 2014, the Company implemented a plan to vacate and sub-lease office space at its 810 Seventh Avenue location in New York, NY. On May 22, 2014, the Company entered into a sub-lease agreement for approximately one-half of the office space at this location and had vacated and relinquished the premises to the sub-tenant as of June 30, 2014. At June 30, 2014, future rent obligations for the vacated space under the Company’s Prime Lease over the remaining lease term of 81 months totaled approximately $3.6 million. Under its new sub-lease agreement for the vacated space the Company will receive future sub-lease rental receipts totaling approximately $2.6 million, resulting in net future cash outflows of approximately $1.0 million. In accordance with ASC 420, Exit or Disposal Cost Obligations, the Company calculated the fair value of the remaining net cash flow liability for the vacated space and recorded a lease restructuring reserve of approximately $0.9 million. Additionally, during the quarter ended June 30, 2014, the Company recorded contract termination costs related to the sub-lease of approximately $150,000 and wrote off approximately $50,000 of unamortized leasehold improvements related to the vacated space. The expenses related to this lease restructuring have been recorded in Selling, general and administrative on the Condensed Consolidated Statements of Operations while the fair value of the liability has been included in both Accrued expenses and Other non-current liabilities on the Condensed Consolidated Balance Sheets.

The following table provides the year-to-date activity of the Company’s restructuring reserves as of June 30, 2014:

(in thousands)
 
Employee
 Costs
   
Operating
 Lease
 
Reserve balance as of December 31, 2013
 
$
2,019
   
$
 
Charges
   
722
     
855
 
Payments / utilizations
   
(1,287
)
   
 
Reserve balance as of June 30, 2014
 
$
1,454
   
$
855
 
 
(7) Stockholders’ Equity

Stock Issuances

Reverse Stock Split

On February 24, 2014, shareholders of the Company approved, through a shareholder vote, an amendment to the Company’s Amended and Restated Certificate of Incorporation authorizing the Board of Directors to effect a reverse stock split of Delcath’s common stock. The reverse stock split became effective on April 8, 2014 at which time Delcath’s common stock began trading on the NASDAQ Stock Exchange on a one-for-sixteen (1:16) split-adjusted basis. All owners of record as of the close of the NASDAQ market on April 8, 2014 received one issued and outstanding share of Delcath common stock in exchange for sixteen issued and outstanding shares of Delcath common stock. No fractional shares were issued in connection with the reverse stock split. All fractional shares created by the one-for-sixteen exchange were rounded up to the next whole share. The reverse stock split had no impact on the number of common shares authorized or the par value per share of Delcath common stock, which remain 170,000,000 and $0.01, respectively. All current and prior period amounts related to shares, share prices and earnings per share, presented in these Condensed Consolidated Financial Statements and the accompanying Notes, have been restated to give retrospective presentation for the reverse stock split.

At-the-Market (“ATM”) Programs

In December 2011, the Company entered into an agreement with Cowen and Company, LLC (“Cowen”) to sell shares of its common stock, par value $.01 per share, from time to time, through an ATM equity offering program having aggregate sales proceeds of $39.8 million, under which Cowen would act as sales agent. During the first quarter of 2013, the Company sold approximately 14.2 million shares of its common stock under this ATM program for proceeds of approximately $20.9 million, with net cash proceeds after related expenses of approximately $20.8 million, and successfully completed the program. As of March 31, 2013, there were no shares of common stock of the Company remaining for sale under this ATM program.
DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements
 
In March 2013, the Company entered into a new agreement with Cowen to sell shares of the Company’s common stock, par value $.01 per share, from time to time, through an ATM equity offering program having aggregate sales proceeds of $50.0 million, under which Cowen will act as sales agent. During the year ended December 31, 2013, the Company sold approximately 1.0 million shares of its common stock under this ATM program for proceeds of approximately $5.0 million, with net cash proceeds after related expenses of approximately $4.8 million. During the first quarter of 2014 the Company sold an additional 1.0 million shares of its common stock under this ATM program for proceeds of approximately $4.4 million, with net cash proceeds after related expenses of approximately $4.4 million. The shares were issued pursuant to an effective registration statement on Form S-3 (333-187230). The net proceeds will be used for general corporate purposes, including, but not limited to, commercialization of our products, obtaining regulatory approvals, funding of our clinical trials, capital expenditures and working capital. There were no shares of common stock sold under the ATM program during the second quarter of 2014. As of June 30, 2014, the Company has approximately $40.4 million remaining under the program.

Committed Equity Financing Facility (“CEFF”) Program

In December 2012, the Company entered into an agreement with Terrapin Opportunity, L.P. (“Terrapin”) for a CEFF program. Under the agreement Terrapin committed to purchase up to $35.0 million of Delcath common stock over a 24-month term. Since inception, the Company has sold approximately 0.5 million shares of its common stock through the program for total proceeds of approximately $11.1 million, with net cash proceeds after related expenses of approximately $10.8 million. As a result, there was approximately $23.9 million available under this CEFF program as of June 30, 2014. The shares were issued pursuant to an effective registration statement on Form S-3 (333-183675). The net proceeds will be used for general corporate purposes including, but not limited to, commercialization of our products, obtaining regulatory approvals, funding of our clinical trials, capital expenditures and general working capital needs.

Warrants

In June 2009, the Company completed the sale of 0.1 million shares of its common stock and the issuance of warrants to purchase 0.1 million common shares (the “2009 Warrants”) pursuant to a subscription agreement with a single investor. The Company received proceeds of $3.0 million, with net cash proceeds after related expenses from this transaction of approximately $2.7 million. Of those proceeds, the Company allocated an estimated fair value of $2.2 million to the 2009 Warrants. As required by the 2009 Warrant agreement, the exercise price of the warrants was adjusted following the Company’s October 2013 sale of common stock and warrants. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. During the six months ended June 30, 2014, 35,000 2009 Warrants were exercised for net proceeds of approximately $0.1 million. The 2009 Warrants had a five-year term which expired on June 15, 2014. The remaining liability after warrant exercises was credited to pre-tax derivative instrument income.

In May 2012, the Company completed the sale of 1.0 million shares of its common stock and the issuance of warrants to purchase 0.3 million common shares (the “2012 Warrants”) pursuant to an underwriting agreement. The Company received proceeds of $21.5 million, with net cash proceeds after related expenses from this transaction of approximately $21.1 million. Of those proceeds, the Company allocated an estimated fair value of $3.4 million to the 2012 Warrants. As required by the 2012 Warrant agreement, the exercise price of the warrants was adjusted following the Company’s October 2013 sale of common stock and warrants. At June 30, 2014, the 2012 Warrants were exercisable at $2.56 per share with approximately 260,000 warrants outstanding. The 2012 Warrants have a three-year term. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. During the six months ended June 30, 2014, approximately 13,000 2012 Warrants were exercised for net proceeds of approximately $34,000.

In October 2013, the Company completed the sale of 1.3 million shares of its common stock and the issuance of warrants to purchase 0.6 million common shares (the “2013 Warrants”) pursuant to a placement agency agreement. The Company received proceeds of $7.5 million, with net cash proceeds after related expenses from this transaction of approximately $6.9 million. Of those proceeds, the Company allocated an estimated fair value of $1.9 million to the 2013 Warrants. The 2013 Warrants became exercisable on April 30, 2014 and at June 30, 2014, the 2013 Warrants were exercisable at $7.04 per share with 0.6 million warrants outstanding. The 2013 Warrants have a five-year term. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. There were no 2013 Warrants exercised during the six months ended June 30, 2014.
DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements

Stock Incentive Plans

The Company established the 2004 Stock Incentive Plan and the 2009 Stock Incentive Plan (collectively, the “Plans”) under which 187,500, and 406,250 shares, respectively, have been reserved for the issuance of stock options, stock appreciation rights, restricted stock, stock grants and other equity awards. The Plans are administered by the Compensation and Stock Option Committee of the Board of Directors which determines the individuals to whom awards shall be granted as well as the type, terms, conditions, option price and the duration of each award.

A stock option grant allows the holder of the option to purchase a share of the Company’s common stock in the future at a stated price. Options granted under the Plans vest as determined by the Company’s Compensation and Stock Option Committee and expire over varying terms, but not more than ten years from the date of grant. Stock option activity for the six months ended June 30, 2014 is as follows:
 
 
 
Stock Option Activity under the Plans
 
 
 
Stock
Options
   
Exercise
Price
per Share
   
Weighted
Average
Exercise
Price
   
Weighted
Average
Remaining
Life
(Years)
 
Outstanding at December 31, 2013
   
252,158
   
$
4.80 — $248.64
   
$
57.90
     
7.36
 
Granted
   
     
     
         
Forfeited
   
(52,303
)
 
$
5.92 — $248.64
     
75.99
         
Expired
   
(625
)
 
$
58.56 — $58.56
     
58.56
         
Outstanding at June 30, 2014
   
199,230
   
$
4.80 — $248.64
   
$
53.16
     
7.08
 
 
For the three and six months ended June 30, 2014, the Company recognized compensation expense of approximately $0.1 million and $0.3 million, respectively, relating to stock options granted to employees.  For the three and six months ended June 30, 2013, the Company recognized compensation expense of approximately $0.1 million and $0.6 million, respectively, relating to stock options granted to employees.

There were no options granted during the six months ended June 30, 2014. The estimated fair value of each option award granted during the six month period ended June 30, 2013 was determined on the date of grant using an option pricing model with the following assumptions:
 
 
 
Six months ended
June 30, 2013
 
Dividend yield
 
None
 
Expected volatility
   
86.16% — 93.68%
Weighted average volatility
   
86.21%
 
Risk-free interest rates
   
0.99% — 1.36%
 
Expected life (in years)
   
6.8
 
 
No dividend yield was assumed because the Company has never paid a cash dividend on its common stock and does not expect to pay dividends in the foreseeable future. Volatilities were developed using the Company’s historical volatility. The risk-free interest rate was developed using the U.S. Treasury yield for periods equal to the expected life of the stock options on the grant date. The expected option term for grants made during the second half of 2012 and thereafter is based on actual historical results. The expected option term for grants made prior to that was developed based on the mid-point between the vesting date and the expiration date of each respective grant as permitted under ASC 718. This method of determining the expected holding period was utilized at that time because the Company did not yet have sufficient historical experience from which to estimate the period.

DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements
 
Restricted stock activity for the six months ended June 30, 2014 is as follows:
 
 
 
Restricted Stock Activity
under the Plans
 
 
 
Restricted
Stock
   
Weighted Average
Grant Date
Fair Value
 
Non-vested at December 31, 2013
   
20,347
   
$
16.84
 
Granted
   
     
 
Vested
   
(17,233
)
   
12.70
 
Forfeited
   
(393
)
   
38.24
 
Non-vested at June 30, 2014
   
2,721
   
$
39.98
 

For the three and six months ended June 30, 2014, the Company recognized compensation expense of approximately $0.02 million and $0.06 million, respectively, related to restricted stock granted to employees.  For the three and six months ended June 30, 2013, the Company recognized compensation expense of approximately $0.1 million and $0.2 million, respectively, related to restricted stock granted to employees.

(8) Fair Value Measurements

Derivative Warrant Liability

As disclosed in Note 7 Stockholders’ Equity of these Condensed Consolidated Financial Statements, the Company allocated part of the proceeds of public offerings in 2009, 2012 and 2013 of the Company’s common stock to warrants issued in connection with those transactions. The valuation of the warrants was determined using an option pricing model. This model uses inputs such as the underlying price of the shares issued when the warrant is exercised, volatility, risk free interest rate and expected life of the instrument. The Company has determined that the warrants should be classified as liabilities and has accounted for them as derivative instruments in accordance with ASC 815. Additionally, the Company has determined that the warrant derivative liability should be classified within Level 3 of the fair-value hierarchy by evaluating each input for the option pricing model against the fair-value hierarchy criteria and using the lowest level of input as the basis for the fair-value classification as called for in ASC 820. There are six inputs: closing price of Delcath stock on the day of evaluation; the exercise price of the warrants; the remaining term of the warrants; the volatility of Delcath’s stock over that term; annual rate of dividends; and the riskless rate of return. Of those inputs, the exercise price of the warrants and the remaining term are readily observable in the warrant agreements. The annual rate of dividends is based on the Company’s historical practice of not granting dividends. The closing price of Delcath stock would fall under Level 1 of the fair-value hierarchy as it is a quoted price in an active market (ASC 820-10). The riskless rate of return is a Level 2 input as defined in ASC 820-10, while the historical volatility is a Level 3 input as defined in ASC 820. Since the lowest level input is a Level 3, Delcath determined the warrant derivative liability is most appropriately classified within Level 3 of the fair value hierarchy.

For the three and six months ended June 30, 2014, the Company recorded pre-tax derivative warrant income of $1.3 million and $1.1 million, respectively. The resulting derivative warrant liabilities totaled $1.1 million at June 30, 2014. In the event of a hypothetical 10% increase in the market price of our common shares on which the June 30, 2014 valuation was based, the value of the derivative liability would have increased by $0.2 million. Management expects that the warrants will either be exercised or expire worthless. The fair value of the warrants at June 30, 2014 was determined by using an option pricing model with the following assumptions:

 
 
2013
Warrants
   
2012
Warrants
 
Expected volatility
   
94.18%
   
111.35%
 
Risk-free interest rates
   
1.34%
 
   
0.11%
 
Expected life (in years)
   
4.33
     
0.92
 
 
Money Market Funds

The Company has determined that the inputs associated with the fair value determination of its money market funds are based on quoted prices (unadjusted) and, as a result, the investments have been classified within Level 1 of the fair value hierarchy.
DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements

The table below presents the Company’s assets and liabilities measured at fair value on a recurring basis as of June 30, 2014, aggregated by the level in the fair value hierarchy within which those measurements fall.

 
Assets and Liabilities Measured at Fair Value
on a Recurring Basis
 
(in thousands)
Level 1
 
Level 2
 
Level 3
 
Balance at
June 30, 2014
 
Assets
 
 
 
 
Money market funds
 
$
1,945
   
$
   
$
   
$
1,945
 
Liabilities
                               
Warrant liability
 
$
   
$
   
$
1,075
   
$
1,075
 
 
The table below presents the activity within Level 3 of the fair value hierarchy for the six months ended June 30, 2014:

Fair Value Measurements Using Significant Unobservable Inputs (Level 3)
 
(in thousands)
 
Warrant
Liability
 
Beginning balance as of December 31, 2013
 
$
2,310
 
Total change in the fair value of the liability included in earnings, including warrant expirations
   
(1,092
)
Fair value of warrants exercised
   
(143
)
Ending balance as of June 30, 2014
 
$
1,075
 
 
 
(9)
Net Loss per Common Share

Basic net loss per share is determined by dividing net loss by the weighted average shares of common stock outstanding during the period. Diluted net loss per share is determined by dividing net loss by diluted weighted average shares outstanding. Diluted weighted average shares reflects the dilutive effect, if any, of potentially dilutive common shares, such as stock options and warrants calculated using the treasury stock method. In periods with reported net operating losses, all common stock options and warrants are deemed anti-dilutive such that basic net loss per share and diluted net loss per share are equal. However, in certain periods in which the exercise price of the warrants was less than the last reported sales price of Delcath’s common stock on the final trading day of the period and there is a gain recorded pursuant to the change in fair value of the warrant derivative liability, the impact of gains related to the mark-to-market adjustment of the warrants outstanding at the end of the period is reversed and the treasury stock method is used to determine diluted earnings per share.

The calculation of net loss and the number of shares used to compute basic and diluted earnings per share for the three and six month periods ended June 30, 2014 and 2013 are as follows:

 
 
Three months ended
June 30,
   
Six months ended
June 30,
 
(in thousands, except share data)
 
2014
   
2013
   
2014
   
2013
 
Net loss – basic
 
$
(4,600
)
 
$
(5,482
)
 
$
(9,878
)
 
$
(18,328
)
Adjustment for gain on warrant derivative liability
   
(356
)
   
     
(363
)
   
 
Net loss – diluted
 
$
(4,956
)
 
$
(5,482
)
 
$
(10,241
)
 
$
(18,328
)
 
                               
Weighted average shares outstanding – basic
   
9,426,169
     
6,023,785
     
9,363,123
     
5,683,380
 
Adjustment for warrant exercises
   
54,764
     
     
99,594
     
 
Weighted average shares outstanding – diluted
   
9,480,933
     
6,023,785
     
9,462,717
     
5,683,380
 
 
                               
Net loss per share – basic
 
$
(0.49
)
 
$
(0.91
)
 
$
(1.06
)
 
$
(3.22
)
Net loss per share – diluted
 
$
(0.52
)
 
$
(0.91
)
 
$
(1.08
)
 
$
(3.22
)
DELCATH SYSTEMS, INC.
Notes to the Condensed Consolidated Financial Statements
 
The following potentially dilutive securities were excluded from the computation of earnings per share as of June 30, 2014 and 2013 because their effects would be anti-dilutive:

 
 
June 30,
 
 
 
2014
   
2013
 
Stock options
   
199,230
     
323,417
 
Unvested restricted shares
   
2,721
     
24,797
 
Warrants
   
589,500
     
339,994
 
Total
   
791,451
     
688,208
 
 
(10)
Taxes

As discussed in Note 13 Income Taxes of the Company’s Annual Report, the Company has a valuation allowance against the full amount of its net deferred tax assets.   The Company currently provides a valuation allowance against deferred tax assets when it is more likely than not that some portion or all of its deferred tax assets will not be realized. The Company has not recognized any unrecognized tax benefits in its balance sheet.

The Company is subject to income tax in the U.S., as well as various state and international jurisdictions. The Company has not been audited by the U.S. Internal Revenue Service, international tax authorities, or any states in connection with income taxes. The Company’s New York State tax returns have been subject to annual desk reviews which have resulted in insignificant adjustments to the related franchise tax liabilities and credits. The Company’s tax years generally remain open to examination for all federal, state and foreign tax matters until its net operating loss carryforwards are utilized and the applicable statutes of limitation have expired. The federal and state tax authorities can generally reduce a net operating loss (but not create taxable income) for a period outside the statute of limitations in order to determine the correct amount of net operating loss which may be allowed as a deduction against income for a period within the statute of limitations.

(11) Commitment and Contingencies

The Company is a party to several legal proceedings. Refer to Part II, Item 1 Legal Proceedings in this Quarterly Report on Form 10-Q for more information.
 
(12)
Subsequent Events

The Company completed an evaluation of the impact of any subsequent events through the date financial statements were issued and determined there were no other subsequent events requiring disclosure in or adjustment to these financial statements.
DELCATH SYSTEMS, INC.
 
Item 2
Management’s Discussion and Analysis of Financial Condition and Results of Operations

The following discussion and analysis of the Company’s financial condition and results of operations should be read in conjunction with the unaudited interim condensed consolidated financial statements and notes thereto contained in Item 1 of Part I of this Quarterly Report on Form 10-Q and the audited financial statements and notes thereto as of and for the year ended December 31, 2013 included in the Company’s 2013 Annual Report on Form 10-K to provide an understanding of its results of operations, financial condition and cash flows.

Disclosure Regarding Forward-Looking Statements

This Quarterly Report on Form 10-Q for the period ended June 30, 2014 contains certain “forward-looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995 with respect to our business, financial condition, liquidity and results of operations. Words such as “anticipates,” “expects,” “intends,” “plans,” “predicts,” “believes,” “seeks,” “estimates,” “could,” “would,” “will,” “may,” “can,” “continue,” “potential,” “should,” and the negative of these terms or other comparable terminology often identify forward-looking statements. Statements in this Quarterly Report on Form 10-Q for the period ending June 30, 2014 that are not historical facts are hereby identified as “forward-looking statements” for the purpose of the safe harbor provided by Section 21E of the Exchange Act and Section 27A of the Securities Act. These forward-looking statements are not guarantees of future performance and are subject to risks and uncertainties that could cause actual results to differ materially from the results contemplated by the forward-looking statements, including the risks discussed in this Quarterly Report on Form 10-Q for the period ended June 30, 2014 in Part II, Item 1A under “Risk Factors” as well as in Part I, Item 3 “Quantitative and Qualitative Disclosures About Market Risk,” our Annual Report on Form 10-K for the period ended December 31, 2013  in Item 1A under “Risk Factors” as well as in Item 7A “Quantitative and Qualitative Disclosures About Market Risk,” and the risks detailed from time to time in our future SEC reports. These forward-looking statements include, but are not limited to, statements about:
 
o our estimates regarding sufficiency of our cash resources, anticipated capital requirements and our need for additional financing;
 
o the commencement of future clinical trials and the results and timing of those clinical trials;
 
o the progress and results of our research and development programs;
 
o submission and timing of applications for regulatory approval and approval thereof;
 
o our ability to successfully source certain components of the system and enter into supplier contracts;
 
o our ability to successfully manufacture CHEMOSAT/Melphalan HDS;
 
o our ability to successfully commercialize CHEMOSAT/Melphalan HDS, generate revenue and successfully obtain reimbursement for the procedure and System;
 
o our ability to successfully negotiate and enter into agreements with distribution, strategic and corporate partners; and

o our estimates of potential market opportunities and our ability to successfully realize these opportunities.
 
Many of the important factors that will determine these results are beyond our ability to control or predict. You are cautioned not to put undue reliance on any forward-looking statements, which speak only as of the date of this Quarterly Report on Form 10-Q. Except as otherwise required by law, we do not assume any obligation to publicly update or release any revisions to these forward-looking statements to reflect events or circumstances after the date of this Quarterly Report on Form 10-Q or to reflect the occurrence of unanticipated events.

Overview
The following section should be read in conjunction with Part I, Item 1: Condensed Consolidated Financial Statements of this report as well as Part I, Item 1: Business; and Part II, Item 8: Financial Statements and Supplementary Data of the Company’s 2013 Annual Report on Form 10-K.
DELCATH SYSTEMS, INC.
 
Delcath Systems, Inc. is a specialty pharmaceutical and medical device company focused on oncology. Our proprietary product—Melphalan Hydrochloride for Injection for use with the Delcath Hepatic Delivery System (Melphalan HDS)—is designed to administer high dose chemotherapy to the liver, while controlling the systemic exposure to those agents. The Company's principal focus is on the treatment of primary and metastatic liver cancers.
 
In the United States, Melphalan HDS is considered a combination drug and device product, and is regulated as a drug by the United States Food and Drug Administration (FDA). Melphalan HDS has not been approved for sale in the United States. In Europe, our proprietary system to deliver and filter melphalan hydrochloride is marketed as a device under the trade name Delcath Hepatic CHEMOSAT® Delivery System for Melphalan (CHEMOSAT). In April 2012, we obtained authorization to affix a CE Mark for Generation Two CHEMOSAT.  The right to affix the CE Mark allows the Company to market and sell CHEMOSAT in Europe. The Company has initiated plans to investigate Melphalan HDS for primary liver cancer.

About CHEMOSAT/Melphalan HDS
CHEMOSAT and Melphalan HDS administer concentrated regional chemotherapy to the liver. This “whole organ” therapy is performed by first isolating the circulatory system of the liver, infusing the liver with chemotherapeutic agent, and filtering the blood prior to returning it to the patient. During the procedure, known as percutaneous hepatic perfusion (PHP), three catheters are placed percutaneously through standard interventional radiology techniques. The catheters temporarily isolate the liver from the body’s circulatory system, allow administration of the chemotherapeutic agent melphalan hydrochloride directly to the liver, and collect blood exiting the liver for filtration by proprietary filters. The filters reduce the concentration of chemotherapeutic agent in the blood, thereby reducing systemic exposure to the drug, and related toxic side-effects, before the filtered blood is returned to the patient’s circulatory system.

Treatment with CHEMOSAT/Melphalan HDS
Currently there are few effective treatment options for cancers in the liver. Traditional treatment options include surgery, chemotherapy, liver transplant, radiation therapy, interventional radiology techniques, and isolated hepatic perfusion. The most advanced application for which CHEMOSAT/Melphalan HDS was evaluated is for the treatment of metastatic melanoma in the liver.  During the Company’s clinical trials, the procedure typically took approximately two to three hours. Patients remained in the intensive care unit overnight for observation after undergoing treatment with CHEMOSAT/Melphalan HDS. Treatment with the CHEMOSAT/Melphalan HDS is a repeatable procedure, and during clinical trials patients received an average of three procedures at approximately four to eight week intervals. A new disposable CHEMOSAT/Melphalan HDS system is used for each treatment.

Risks associated with CHEMOSAT/Melphalan HDS Procedure
As with many cancer therapies, treatment with CHEMOSAT/Melphalan HDS is associated with toxic side-effects and certain risks, some of which are potentially life-threatening. In Phase 1, 2, and 3 clinical trials using early versions of Melphalan HDS, the integrated safety population of patients treated with early versions of  CHEMOSAT/Melphalan HDS showed these risks to include: a 4.1% incidence of deaths due to adverse reactions; 4% incidence of stroke; 2% incidence of myocardial infarction in the setting of an incomplete cardiac risk assessment; a ≥ 70% incidence of grade 4 bone marrow suppression with a median time of recovery of greater than 1 week; and 8% incidence of febrile neutropenia, along with the additive risk of hepatic injury, severe hemorrhage, and gastrointestinal perforation. In this integrated safety population, deaths due to certain adverse reactions did not occur again during the clinical trials following the adoption of related protocol amendments. The trials that comprised this integrated safety population used early versions of CHEMOSAT/Melphalan HDS, including the Generation One filter, and did not include use of the Generation Two filter. The Company believes that the use of the Generation Two filter and comprehensive multidisciplinary training, the risks commonly associated with the procedure can be managed by experienced clinicians.

In clinical development, the Expanded Access Program (EAP) and compassionate use in the United States, Melphalan HDS has been used to treat 175 patients. In the Phase 1, 2, and 3 trials early versions of the System were utilized, while the EAP and compassionate use utilized the Generation Two filter.
 
Regulatory Status

United States

In August 2012, we submitted our New Drug Application (NDA) for the Melblez Kit under Section 505(b)(2) of the Federal Food Drug Cosmetic Act (FFDCA) seeking an indication for the percutaneous intra-arterial administration of melphalan for use in the treatment of patients with metastatic melanoma in the liver, and subsequently amended the indication we are seeking to ocular melanoma metastatic to the liver. The Company’s NDA was accepted for filing by the Food and Drug Administration (FDA) on October 15, 2012, and was designated for standard review with an initial Prescription Drug User Fee Act (PDUFA) goal date of June 15, 2013. On April 3, 2013, the FDA extended its PDUFA goal date to September 13, 2013. The FDA’s Oncologic Drugs Advisory Committee (ODAC) reviewed our NDA on May 2, 2013, and voted 16 to 0, with no abstentions, that the benefits of treatment with the Melblez Kit do not outweigh the risks associated with the procedure. It should be noted that the data submitted to the FDA used the early clinical trial versions of the system along with early clinical procedure techniques. On September 12, 2013, the FDA issued a Complete Response Letter (CRL) regarding the Company’s NDA for Melblez Kit.
DELCATH SYSTEMS, INC.
 
A CRL is issued by the FDA when the review of a file is completed and questions remain that precludes approval of the NDA in its current form. The FDA comments included, but were not limited to, a statement that Delcath must perform another "well-controlled randomized trial(s) to establish the safety and efficacy of Melblez Kit using overall survival as the primary efficacy outcome measure," and which "demonstrates that the clinical benefits of Melblez Kit outweigh its risks." The FDA also requires that the additional clinical trial(s) be conducted using the product the Company intends to market. The Company held a meeting with FDA to clarify components of the CRL, during which it confirmed its understanding of device and procedure safety requirements contained in the CRL. Delcath is incorporating the requirements contained in the CRL into its clinical development program. The Company is also evaluating the best path forward for an indication in ocular melanoma that is metastatic to the liver. We continue to believe that such an approval would meet a high unmet need in the United States.

In the United States, Melphalan HDS is subject to regulation as a combination product, which means it is composed of both a drug product and device product. If marketed individually, each component would therefore be subject to different regulatory pathways and reviewed by different centers within the FDA. A combination product, however, is assigned to a center that will have primary jurisdiction over its pre-market review and regulation based on a determination of its primary mode of action, which is the single mode of action that provides the most important therapeutic action. In the case of Melphalan HDS, the primary mode of action is attributable to the drug component of the product, which means that the Center for Drug Evaluation and Research (CDER) has primary jurisdiction over its pre-market development and review and the Company must pursue a new drug application pathway.

The process required by the FDA before drug product candidates may be marketed in the United States generally involves the following:
 
o submission to the FDA of an investigational new drug application, or IND, which must become effective before human clinical trials may begin and must be updated annually;
 
o completion of extensive preclinical laboratory tests and preclinical animal studies, all performed in accordance with the FDA’s Good Laboratory Practice, or GLP, regulations;
 
o performance of adequate and well-controlled human clinical trials to establish the safety and efficacy of the product candidate for each proposed indication;
 
o submission to the FDA NDA, after completion of all pivotal clinical trials;
 
o a determination by the FDA within 60 days of its receipt of an NDA to file the NDA for review;
 
o satisfactory completion of an FDA pre-approval inspection of the manufacturing facilities at which the product is produced and tested to assess compliance with current good manufacturing practice, or cGMP, regulations; and
 
o FDA review and approval of an NDA prior to any commercial marketing or sale of the drug in the United States.
 
Drug development and regulatory approval is an inherently uncertain process with a high risk of failure at every stage of development.  The development and approval process requires substantial time, effort and financial resources, and we cannot be certain that any approvals for our product will be granted at all or on a timely basis.
 
Orphan Drug Exclusivity
 
Some jurisdictions, including the United States, may designate drugs for relatively small patient populations as orphan drugs. Pursuant to the Orphan Drug Act, the FDA grants orphan drug designation to drugs intended to treat a rare disease or condition, which is generally a disease or condition that affects fewer than 200,000 individuals in the United States. The orphan designation is granted for a combination of a drug entity and an indication and therefore it can be granted for an existing drug with a new (orphan) indication. Applications are made to the Office of Orphan Products Development at the FDA and a decision or request for more information is rendered in 60 days. NDAs for designated orphan drugs are exempt from user fees, obtain additional clinical protocol assistance, are eligible for tax credits up to 50% of research and development costs, and are granted a seven-year period of exclusivity upon approval. The FDA cannot approve the same drug for the same condition during this period of exclusivity, except in certain circumstances where a new product demonstrates superiority to the original treatment. Exclusivity begins on the date that the marketing application is approved by the FDA for the designated orphan drug, and an orphan designation does not limit the use of that drug in other applications outside the approved designation in either a commercial or investigational setting.
DELCATH SYSTEMS, INC.
 
The FDA has granted Delcath five orphan drug designations. In November 2008, the FDA granted Delcath two orphan drug designations for the drug melphalan for the treatment of patients with cutaneous melanoma as well as patients with ocular melanoma. In May 2009, the FDA granted Delcath an additional orphan drug designation of the drug melphalan for the treatment of patients with neuroendocrine tumors. In August 2009, the FDA granted Delcath an orphan drug designation of the drug doxorubicin for the treatment of patients with primary liver cancer. In October 2013, the FDA granted Delcath orphan drug designation of the drug melphalan for the treatment of hepatocellular carcinoma.

The granting of orphan drug designation does not mean that the FDA has approved a new drug. Companies must still pursue the rigorous development and approval process which requires substantial time, effort and financial resources, and we cannot be certain that any approvals for our product will be granted on a timely basis, if at all.
 
European Regulation
 
In the European Economic Area (EEA), CHEMOSAT is subject to regulation as a medical device. The EEA is composed of the 28 Member States of the European Union plus Norway, Iceland and Liechtenstein. Under the EU Medical Devices Directive (Directive No 93/42/ECC of 14 June 1993, as last amended), drug delivery products such as CHEMOSAT are governed by the EU laws on pharmaceutical products only if they are (i) placed on the market in such a way that the device and the pharmaceutical product form a single integral unit which is intended exclusively for use in the given combination, and (ii) the product is not reusable. In such cases, the drug delivery product is governed by the EU Code on Medicinal Products for Human Use (Directive 2001/83/EC, as last amended), while the essential requirements of the EU Medical Devices Directive apply to the safety and performance-related device features of the product. Because we do not intend to place CHEMOSAT on the EEA market as a single integral unit with melphalan, the product is governed solely by the EU Medical Devices Directive, while the separately marketed drug is governed by the EU Code relating to Medicinal Products for Human Use and other EU legislation applicable to drugs for human use.

CHEMOSAT is regulated as a Class IIb medical device. As a Class IIb medical device, a Notified Body is not required to carry out an examination of the product’s design dossier as part of its conformity assessment prior to commercialization. The Company must continue to comply with the essential requirements of the EU Medical Devices Directive (Directive 93/42 EC) and is subject to a conformity assessment procedure requiring the intervention of a Notified Body.  The conformity assessment procedure for Class IIb medical devices requires the manufacturer to apply for the assessment of its quality system for the design, manufacture and inspection of its medical devices by a Notified Body.  The Notified Body will audit the system to determine whether it conforms to the provisions of the Medical Devices Directive.  If the Notified Body’s assessment is favorable it will issue a Full Quality Assurance Certificate, which enables the manufacturer to draw a Declaration of Conformity and affix the CE mark to the medical devices covered by the assessment. Thereafter, the Notified Body will carry out periodic audits to ensure that the approved quality system is applied by the manufacturer.

Under the regulatory scheme in the EEA, the Company has received authorization to affix the CE Mark to CHEMOSAT as a device only, and physicians must separately obtain melphalan for use with CHEMOSAT. Our ability to market and promote CHEMOSAT is limited to this approved indication. Melphalan Hydrochloride for Injection is currently approved in 14 member states of the EEA, including the seven markets where procedures have been performed.
 
No melphalan labels in the EEA reference our product, and the labels vary from country to country with respect to the approved indication of the drug and its mode of administration. In the exercise of their professional judgment in the practice of medicine, physicians are generally allowed, under certain conditions, to use or prescribe a product in ways not approved by regulatory authorities. Physicians intending to use CHEMOSAT must obtain and use melphalan independently at their discretion.
DELCATH SYSTEMS, INC.
 
Other International Regulations
 
CHEMOSAT has received registrations in the following countries: Australia, New Zealand, Argentina, Taiwan, and Singapore. With limited resources and our attention focused on European commercial and clinical adoption efforts, pursuing other markets at this time is not practical. The Company will continue to evaluate commercial opportunities in these and other markets when resources are available and at an appropriate time.
 
Clinical Development Program
 
The primary focus of the Company’s Clinical Development Program (CDP) is to obtain clinical data for CHEMOSAT/Melphalan HDS in various disease states to support regulatory approvals in various jurisdictions, including the U.S. and to support clinical adoption and reimbursement in Europe.   Currently, the Company’s efforts are primarily directed towards initiating a global Phase 2 clinical program to study CHEMOSAT/Melphalan HDS for the treatment of hepatocellular carcinoma and supporting Investigator Initiated Trials (IITs) as deemed appropriate. 

Clinical trials are long, expensive and highly uncertain processes and failure can unexpectedly occur at any stage of clinical development. The start or end of a clinical trial is often delayed or halted due to changing regulatory requirements, manufacturing challenges, required clinical trial administrative actions, slower than anticipated patient enrollment, changing standards of care, availability or prevalence of use of a comparator treatment or required prior therapy.
 
Hepatocellular Carcinoma (HCC)
 
HCC is one of the most prevalent and lethal forms of cancer. According to the American Cancer Society’s (ACS) Cancer Facts & Figures 2013, an estimated 30,000 new cases of HCC (including intrahepatic bile duct cancers) were expected to occur in the U.S. during 2013, and the overall five-year survival rate for liver cancer patients in the U.S is approximately 15% compared to 68% for all cancer combined. Globally, with 782,000 new cases in 2012, HCC was the fifth most common cancer in men and the ninth in women according to GLOBOCAN. It has been estimated that over 40 percent of all cases of HCC occur in the People's Republic of China, which has an annual incidence of 137,000 cases.  GLOBOCAN estimates indicate that HCC was responsible for 746,000 deaths in 2012 (9.1% of the total cancer deaths), making it the second most common cause of death from cancer worldwide.

The prognosis for liver cancer is very poor, as indicated by an overall ratio of mortality to incidence of 0.95.  The American Cancer Society’s (ACS) Cancer Facts & Figures 2013 outlines the treatment options for HCC as follows: “Early stage HCC can sometimes be successfully treated with surgery in patients with sufficient healthy liver tissue; liver transplantation may also be an option. Surgical treatment of early stage HCC is often limited by pre-existing liver disease that has damaged the portion of the liver not affected by cancer. Patients whose tumors cannot be surgically removed may choose ablation (tumor destruction) or embolization, a procedure that cuts off blood flow to the tumor. Fewer treatment options exist for patients diagnosed at an advanced stage of the disease. Sorafenib (Nexavar) is a targeted drug approved for the treatment of HCC in patients who are not candidates for surgery.”
 
Phase 2 Multi-Histology Clinical Trial - HCC Cohort
 
In the Company’s multi-arm Phase 2 clinical trial, conducted between 2005 and 2010, five patients with HCC were treated with CHEMOSAT/Melphalan HDS in the primary hepatic malignancy cohort.  Among these patients, one patient received four treatments, achieved a partial response lasting 12.22 months, and survived 20.47 months.  Three other patients with stable disease received 3-4 treatments, with hepatic progression free survival (hPFS) ranging 3.45 to 8.15 months, and overall survival (OS) ranging 5.26 to 19.88 months.  There was no evidence of extrahepatic disease progression.  The observed duration of hPFS and OS in this limited number of patients exceeded that generally associated with this patient population, and we believe constitutes a promising signal that warrants further clinical investigation.
 
Phase 2 HCC Program
 
On the basis of these encouraging results, the Company has initiated a new clinical trial program in Europe and intends to initiate a similar program in the U.S., with the goal of obtaining an efficacy and safety signal for Melphalan HDS in the treatment of HCC. The Company is pursuing a staged clinical strategy, starting with a Phase 2 clinical trial program and intends to pursue a Phase 3 trial if the initial responses from the Phase 2 study are positive. 

DELCATH SYSTEMS, INC.
 
Due to differences in treatment practice patterns between Europe and the U.S., the Company has established separate European and U.S. trial protocols for the HCC Phase 2 program with different inclusion and exclusion patient selection criteria. Clinical observations from the two trials are designed to be complementary, and data between the trials will be analyzed collectively to support the anticipated Phase 3 pivotal study design. The first center in Germany, Goethe University Frankfurt, is open for enrollment.  The Company intends to open additional centers in Germany and the U.K., subject to the applicable authorizations and approvals including ethics committee approval at participating hospitals. In the U.S. the Company filed its amended Investigational New Drug (IND) application with the FDA on February 11, 2014 to include the trial protocol for its Phase 2 HCC program. This IND amendment became effective on March 13, 2014. The Company is evaluating several centers in the U.S. and subject to applicable authorizations and approvals including institutional review board (IRB), intends to open the first U.S. site during the second half of 2014. We anticipate data on the first eleven patients from both trials to be available in the first half of 2015, subject to timely enrollment of eligible patients. We expect to enroll patients in our European sites first.

EU Clinical Data Generation
 
In Europe, the Company has completed a retrospective data collection trial which collected data post hoc from two hospitals in Europe where therapy with CHEMOSAT was administered in a non-clinical trial setting.  The study  provided a retrospective view of hematology results from 7 patients treated with CHEMOSAT in Europe. The data, while not part of a formal clinical trial design and limited in nature does provide supporting evidence that the safety of Generation 2 CHEMOSAT and related treatment appeared well tolerated and manageable by practitioners. In addition, the Company is initiating a patient registry, which will prospectively collect data from EU commercial experience. The first hospital submitted the protocol to its Ethics Committee in January 2014 and, pending timely site participation, we anticipate the first site to be enrolling patients onto the registry during the second half of 2014. We believe the Patient Registry will provide valuable data and information from a commercial setting which can be used to support our efforts for clinical adoption and commercialization in Europe.

EU Investigator Initiated Trials

The Company is also presently supporting two IITs across multiple tumor types in Europe and expects to evaluate other IITs as suitable opportunities present in Europe. At present an IIT in colorectal carcinoma (CRC) is open for enrollment at Leiden University Medical Center in The Netherlands and has treated their first patient.  Additionally, an IIT in HCC is open for enrollment at Goethe University Frankfurt in Germany.  The Company believes IITs will serve to build clinical experience at key cancer centers, and will help support efforts to obtain full reimbursement in Europe.
 
Sales and Marketing
 
European Union
 
In April 2011 the Company obtained authorization to affix a CE Mark for Generation One CHEMOSAT. The Company began European commercialization with this version of CHEMOSAT in early 2012 when the first CHEMOSAT procedures performed outside of a clinical trial setting were performed in Italy. In April 2012, the Company obtained authorization to affix a CE Mark for Generation Two CHEMOSAT, and since this time all procedures in Europe have been performed with this version of the system.

With continued economic and reimbursement challenges in certain European markets, the Company’s immediate market access and clinical adoptions efforts are focused on the key target markets of Germany and the United Kingdom, which represent a majority of the total potential liver cancer market (primary and metastatic) in the EU and where progress in securing reimbursement for CHEMOSAT treatments offers the best near-term opportunities.  The Company also continues to support clinical adoption of CHEMOSAT in the Netherlands, Italy, Spain and France.  The Company uses a combination of direct and indirect sales channels to market and sell CHEMOSAT in Europe. In 2013, the Company utilized medical science liaisons through a third party to support our clinical adoption efforts. As part of the Company’s restructuring, the medical science liaison consultant program has been phased out and we have integrated these capabilities into existing resources.  To support our commercialization efforts in the EU, we have established our European Headquarters in Galway, Ireland.
 
Thus far in 2014 CHEMOSAT treatments have been performed in the United Kingdom, Germany, the Netherlands, and Spain. During the first seven months of 2014 there were 50 CHEMOSAT treatments performed with 22 of these representing retreatments, compared to 22 CHEMOSAT treatments performed with 6 of these representing retreatments during the same period of 2013. Since its February 2012 launch in Europe, CHEMOSAT has been used to perform 123 treatments on 81 patients.
DELCATH SYSTEMS, INC.

Since launching CHEMOSAT in Europe, treatments have been performed at 17 leading European cancer centers.

Germany
o University of Heidelberg Hospital
o Berlin Charité Hospital
o University Medical Center Göttingen
o Johann Wolfgang Goethe-University, Frankfurt
o University of Bonn
o Asklepios Clinic Barmbek, Hamburg
o Jena University Hospital, Jena

United Kingdom
o Southampton University Hospital
o SPIRE Southampton Hospital

Italy
o European Institute of Oncology
o Varese University Hospital

The Netherlands
o Netherlands Cancer Institute- Antoni van Leeuwenhoek Hospital
o Leiden University Medical Center

France
o Cancer Institute Gustave Roussy
o Hôpital Saint-André

Spain
o Clinica Rotger Majorca Hospital

Ireland
o University Hospital Galway

Physicians in Europe have used CHEMOSAT to treat patients with a variety of cancers in the liver primarily ocular melanoma liver metastases, and other tumor types, including hepatocellular carcinoma, cholangeocarcinoma, and liver metastases from colorectal cancer, breast, and cutaneous melanoma.
 
European Reimbursement
 
A critical driver of utilization growth for CHEMOSAT in Europe is the expansion of reimbursement mechanisms for the procedure in our priority markets. In Europe, there is no centralized pan-European medical device reimbursement body. Reimbursement is administered on a regional and national basis. In 2013 the Company engaged a third party reimbursement specialist to support efforts in filing for reimbursement coverage. Medical devices are typically reimbursed under diagnosis related groups (DRG) as part of a procedure.  Prior to obtaining permanent DRG reimbursement codes, in certain jurisdictions, the Company is actively seeking interim reimbursement from existing mechanisms that include specific interim reimbursement schemes, new technology payment programs as well as existing DRG codes. In most EU countries, the government provides healthcare and controls reimbursement levels. Since the EU has no jurisdiction over patient reimbursement or pricing matters in its member states, the methodologies for determining reimbursement rates and the actual rates may vary by country.
 
Germany
 
In January 2014, the Company announced that the Institut fϋr das Entgeltsystem im Krankenhaus (InEk), the German federal reimbursement agency, again granted Value 4 coverage status for the treatment of patients with liver metastases with CHEMOSAT. Under the Neue Untersuchungs und Behandlungsmethoden (NUB) reimbursement scheme, Value 4 Status, while not mandating reimbursement, allows participating cancer centers to negotiate a budget to fund reimbursement coverage for CHEMOSAT procedure with insurers serving their region.
DELCATH SYSTEMS, INC.

The InEk determines three status levels for medical procedures submitted for its review: Value 1 (mandated reimbursement), Value 2 (declined for reimbursement), and Value 4 (negotiated reimbursement). The InEk may also decline to make a determination regarding an application. For 2014 reimbursement, a total of 618 medical procedures were submitted to the InEk for consideration under the NUB scheme, with 16% or 96 procedures receiving Value 1 Status, 6% or 36 procedures receiving Value 4, and the remaining 78% denied coverage or un-evaluated. The application for CHEMOSAT was submitted by 71 hospitals in Germany, which represents a significant increase in the level of institutional support the procedure received over 2013.

The InEk first established NUB Value 4 status for CHEMOSAT procedures in 2013, though we have been advised that hospitals did not successfully negotiate reimbursement budgets for CHEMOSAT in 2013. In 2014, we expect the process to be similar to 2013 and have been advised by several hospitals in Germany that they will focus their efforts primarily on NUB Value 1 negotiations rather than NUB 4 negotiations, and accordingly we do not expect there to be significant progress in obtaining reimbursement under NUB 4.. The NUB is an annual process, and participating centers in Germany are required to apply each year for subsequent coverage under the NUB scheme.

Separately, throughout 2014, physicians and patients in Germany continue to submit Individual Funding Requests (IFRs) seeking reimbursement for the treatment of liver metastases with CHEMOSAT. IFRs are case-by-case appeals for reimbursement made to the patient’s insurance carrier (“sickness funds”). While each IFR is evaluated independently, we have been advised that the majority of these applications have been approved in recent months. These approvals have covered a range of sickness funds across a number of regions in Germany including ocular melanoma, cutaneous melanoma, intrahepatic cholangiocarcinoma, pancreatic cancer and sarcoma; and some were granted for multiple treatments of the same patients. We expect that IFRs will continue to be the key reimbursement vehicle in the German market in 2014.

The German Radiology Society resubmitted its application for ZE (Zusatzentgeld) for CHEMOSAT in March 2014. ZE  is a national interim reimbursement code granted by the InEk until a specific Diagnostic Related Group (DRG) code can be created.  A ZE code is dependent on having enough financial data related to the procedure to establish cost averages. We will focus our efforts in 2014 on ensuring that treatment and cost data from specific hospitals is provided to the InEk.
 
United Kingdom
 
In April 2013, interim funding for oncological procedures in the United Kingdom moved away from local Primary Care Trusts (PCTs) to a centralized body of cancer care commissioners. Delcath and its partner centers have identified existing Healthcare Resource Groups (HRG) code(s), which may allow hospitals to be covered for CHEMOSAT related costs. The Company is also working with the HRG organization that decides on new HRG codes with a view to gaining a dedicated and permanent reimbursement code in the future.

The Company is also supporting efforts seeking a block fund grant through the Commissioning Through Evaluation (CTE) process which may provide up to 50-75 ocular melanoma patients to be treated utilizing CHEMOSAT in three centers across the U.K. It is important to note that the CTE process has been driven by partner centers and their clinical community, with the centers applying for funding for a limited number of patients with ocular melanoma. The British healthcare system continues to evolve however, and ongoing changes to the CTE process and funding streams have resulted in delays and made the granting and timing of block funding difficult to predict. The current expectation is for the process to be completed by the end of the third quarter of 2014 with the funding, if any, becoming available in the fourth quarter of 2014. The entire CTE funding mechanism is a new process and these ongoing policy changes in the National Health Service (NHS) make it difficult to predict the likelihood of success in the near term.

In December 2013, the National Institute for Clinical Excellence (NICE), a non-departmental public body that provides guidance and advice to improve health and social care in the UK, initiated a clinical review of CHEMOSAT. NICE issued provisional draft recommendations for the use of CHEMOSAT in the UK, and invited the Company as well as physicians and other interested parties to comment. The NICE recommendations were open for public comment until January 22, 2014, and a decision on final clinical recommendations was made on May 28, 2014 indicating that, as the current body of evidence on the safety and efficacy of chemosaturation via percutaneous hepatic artery perfusion for primary or metastatic liver cancer is limited, the procedure should be performed within the context of research by clinicians with specific training in its use and techniques.  This may take the form of observational studies. With our anticipated Phase 2 HCC trial and the European Registry, we believe the data generated from these studies will help provide supporting clinical data and address the concerns raised by NICE relative to survival, quality of life and adverse events.  NICE may decide to conduct a Technology Appraisal of CHEMOSAT thereafter, the outcome of which could influence the long-term reimbursement status.
DELCATH SYSTEMS, INC.

Despite the NICE recommendations, public patients may continue to be treated in the UK through the Commissioning Through Evaluation (CTE) process or clinical trials. Private patients will continue to be treated through the established private treatment pathway.
 
Other EU Markets
 
Permanent reimbursement coverage in remaining EU markets will require additional time to secure. In the interim period, the Company is seeking payment through various avenues, including new technology programs. In France, the Company has revised its strategy and decided not to pursue a multi-center STIC application. STIC is a hybrid of interim funding and clinical study, allowing a new procedure to be assessed over a two-year period on a pre-set number of treatments. The Company believes that the STIC process would be too time consuming and costly, and that direct pursuit of a DRG code represented a better allocation of Company resources in this market.  The Company will also present its Phase 3 trial data, once published, to the French healthcare authorities in order to assess the possibility of gaining a DRG code without going through the STIC process. In Ireland, the Company is postponing commercialization efforts until a clear reimbursement pathway is identified.

For France and the Netherlands, publication of the Phase 3 trial manuscript is a key component of the reimbursement process. The Company continues to work with the principal investigators on submission of its Phase 3 and Phase 2 clinical trials for publication. The timing of these submissions will be determined by the principal investigators and the Company looks forward to the submission of the publications.

Distribution Partners
 
As a result of the Company’s strategy to prioritize resources on the key direct markets of Germany and the United Kingdom, the Company expects that its distribution strategy will play a lesser role in its current commercial activities. In Spain, the Company has determined that there was no benefit to continuing with an indirect model and therefore terminated its relationship with its distributor in Spain. Similar to our strategy in Germany and United Kingdom, the Company has decided to pursue a direct market approach through a contract sales consultant in Spain as opportunities present.
 
Material Modifications to Rights of Security Holders
 
On February 24, 2014, at a Special Meeting of Stockholders of Delcath Systems, Inc., the Company’s stockholders approved an amendment to the Company’s Amended and Restated Certificate of Incorporation to effect a reverse stock split of the Company’s common stock at a specific ratio within a range from one-for-eight (1:8) to one-for-sixteen (1:16), inclusive, on or prior to December 31, 2014 and granted authorization to the Company’s Board of Directors to determine, in its sole discretion, whether to implement the reverse stock split, as well as its specific timing and ratio.

Following the approval by our stockholders, the Board approved a reverse stock split and on April 8, 2014, the Company, filed a Certificate of Amendment to its Amended and Restated Certificate of Incorporation with the Secretary of State of the State of Delaware (the “Certificate of Amendment”), which effected a reverse stock split of its common stock at a ratio of 1-to-16 (the “Reverse Stock Split”). Trading of the Company’s common stock on The NASDAQ Capital Market on a split-adjusted basis began at the opening of trading on April 9, 2014.

As a result of the Reverse Stock Split, each sixteen shares of common stock was combined into one share of common stock and the total number of shares of common stock outstanding was reduced from approximately 150.9 million shares to approximately 9.4 million shares. No fractional shares were issued if, as a result of the Reverse Stock Split, a registered stockholder was otherwise entitled to a fractional share. Instead, stockholders who were otherwise entitled to receive fractional shares because they held a number of shares not evenly divisible by the ratio of the Reverse Stock Split automatically received an additional share of common stock. In other words, any fractional share was rounded up to the nearest whole number.
 
On April 24, 2014, the Company received a notification letter from The NASDAQ Stock Market advising the Company that the closing bid price of the Company’s common stock had been at $1.00 per share or greater for 10 consecutive business days, and accordingly, the Company had regained compliance with Listing Rule 5550(a)(2) and the matter was considered closed. The Company believes the reverse stock split was necessary in order to maintain the Company’s listing on The NASDAQ Capital Market and to provide resources and flexibility with respect to capital sufficient to execute its business plans and strategy.
DELCATH SYSTEMS, INC.

Results of Operations for the Three and Six Months Ended June 30, 2014; Comparisons of Results of Operations for the Three and Six Months Ended June 30, 2013

Three months ended June 30, 2014 and June 30, 2013

Revenue
 
The Company recorded approximately $0.3 million in revenue related to product sales during the three months ended June 30, 2014. The Company did not record revenue during the same period of 2013.

Cost of Goods Sold
 
During the three months ended June 30, 2014, the Company recorded cost of goods sold of approximately $0.1 million. During the same period in 2013, the Company recorded cost of goods sold of approximately $0.3 million. As Delcath continues progress with clinical adoption in Europe and other parts of the world, the Company expects to see a certain amount of volatility in both the average selling price and gross margin for the next several years. This volatility will be related to several factors, including: adjustments to volume forecasts; the expected use of third party distributors whose purchase prices will be lower than direct-to-customer prices; the gradual increase in cost of goods sold as the Company exhausts raw materials that were purchased and expensed in prior periods and begins to recognize the actual costs of materials, labor and overhead; and an improvement in efficiencies as the Company increases its production of CHEMOSAT.

Selling, General and Administrative Expenses
 
For the three months ended June 30, 2014, selling, general and administrative expenses decreased to $4.6 million compared to $6.3 million for the three months ended June 30, 2013.  The decrease reflects the Company’s efforts to increase organizational efficiencies, including workforce restructurings that took place throughout 2013 and the first six months of 2014, partially offset by the lease restructuring charge the Company recorded in June of 2014.

Research and Development Expenses
For the three months ended June 30, 2014, research and development expenses decreased to $1.5 million compared to $4.0 million for the three months ended June 30, 2013. A significant portion of this reduction related to costs incurred for the Company’s NDA submission to the FDA in 2013. The Company has not incurred any such expenses thus far in 2014. Additional savings were also generated through the Company’s efforts to increase organizational efficiencies, including workforce restructurings that took place throughout 2013 and the first six months of 2014.

Interest Income
Interest income is from a money market account and interest earned on operating accounts. For the three months ended June 30, 2014, the Company had interest income of approximately $1,000 as compared to interest income of approximately $5,000 for the same period in 2013.

Other Expense and Interest Expense
Other expense is primarily related to foreign currency exchange gains and losses. Interest expense is related to an ongoing Revolving Line Facility Fee as required by the Loan and Security Agreement signed with Silicon Valley Bank in 2012 and discussed in Note 9 to the Company’s audited financial statements contained in the 2013 Annual Report on Form 10-K.

Net Loss
The Company had a net loss for the three months ended June 30, 2014, of $4.6 million, a decrease of $0.9 million, or 16%, compared to a net loss of $5.5 million for the same period in 2013. This improvement in earnings is primarily due to a $4.2 million reduction in operating expenses coupled with a $0.5 million improvement in gross profit. As detailed above, the Company has been successful in reducing overall operational costs primarily related to the absence of an NDA filing in 2014 as well as through workforce restructurings that took place over the past twelve months. The savings from these reductions in operating expenses was mostly offset by a $3.8 million decline in derivative instrument income caused by a change in the fair value of the Company’s warrant liability, which is a non-cash expense.
DELCATH SYSTEMS, INC.
 
Six months ended June 30, 2014 and June 30, 2013

Revenue
 
The Company recorded approximately $0.6 million in revenue related to product sales during the six months ended June 30, 2014 compared to approximately $0.1 million of product revenue and $0.3 million of previously deferred revenue related to the Company’s agreement with Chi-Fu Trading Co. Ltd. during the same period of 2013.

Cost of Goods Sold
 
During the six months ended June 30, 2014, the Company recorded cost of goods sold of approximately $0.2 million. During the same period in 2013, the Company recorded cost of goods sold of approximately $0.4 million. As Delcath continues progress with clinical adoption in Europe and other parts of the world, the Company expects to see a certain amount of volatility in both the average selling price and gross margin for the next several years. This volatility will be related to several factors, including: adjustments to volume forecasts; the expected use of third party distributors whose purchase prices will be lower than direct-to- customer prices; the gradual increase in cost of goods sold as the Company exhausts raw materials that were purchased and expensed in prior periods and begins to recognize the actual costs of materials, labor and overhead; and an improvement in efficiencies as the Company increases its production of CHEMOSAT.

Selling, General and Administrative Expenses
 
For the six months ended June 30, 2014, selling, general and administrative expenses decreased to $8.4 million compared to $12.3 million for the six months ended June 30, 2013.  The decrease reflects the Company’s efforts to increase organizational efficiencies, including workforce restructurings that took place throughout 2013 and the first six months of 2014, partially offset by the lease restructuring charge the Company recorded in June of 2014.

Research and Development Expenses
For the six months ended June 30, 2014, research and development expenses decreased to $2.9 million compared to $8.5 million for the six months ended June 30, 2013. A significant portion of this reduction related to costs incurred for the Company’s NDA submission to the FDA in 2013. The Company has not incurred any such expenses thus far in 2014. Additional savings were also generated through the Company’s efforts to increase organizational efficiencies, including workforce restructurings that took place throughout 2013 and the first six months of 2014.

Interest Income
Interest income is from a money market account and interest earned on operating accounts. For the six months ended June 30, 2014, the Company had interest income of approximately $2,000 as compared to interest income of approximately $15,000 for the same period in 2013.

Other Expense and Interest Expense
Other expense is primarily related to foreign currency exchange gains and losses. Interest expense is related to an ongoing Revolving Line Facility Fee as required by the Loan and Security Agreement signed with Silicon Valley Bank in 2012 and discussed in Note 9 to the Company’s audited financial statements contained in the 2013 Annual Report on Form 10-K.
 
Net Loss
The Company had a net loss for the six months ended June 30, 2014, of $9.9 million, a decrease of $8.4 million, or 46%, compared to the a loss of $18.3 million for the same period in 2013. This improvement in earnings is primarily due to a $9.4 million reduction in operating expenses coupled with a $0.4 million improvement in gross profit. As detailed above, the Company has been successful in reducing overall operational costs primarily related to the absence of an NDA filing in 2014 as well as through workforce restructurings that took place over the past twelve months. The savings from these reductions in operating expenses was partially offset by a $1.7 million decline in derivative instrument income caused by a change in the fair value of the Company’s warrant liability, which is a non-cash expense.
DELCATH SYSTEMS, INC.
 
Liquidity and Capital Resources
 
The Company’s future results are subject to substantial risks and uncertainties.  Delcath has operated at a loss for its entire history and anticipates that losses will continue over the coming years.  There can be no assurance that Delcath will ever generate significant revenues or achieve profitability. The Company expects to use cash, cash equivalents and investment proceeds to fund its clinical and operating activities. Delcath’s future liquidity and capital requirements will depend on numerous factors, including the initiation and progress of clinical trials and research and product development programs, obtaining approvals and complying with regulations; the timing and effectiveness of product commercialization activities, including marketing arrangements; the timing and costs involved in preparing, filing, prosecuting, defending and enforcing intellectual property rights; and the effect of competing technological and market developments.

At June 30, 2014, the Company had cash and cash equivalents totaling $27.3 million, as compared to cash, cash equivalents and certificates of deposit totaling $31.2 million and $32.3 million at December 31, 2013 and June 30, 2013, respectively. During the six months ended June 30, 2014, the Company used $8.4 million of cash in its operating activities, which compares to $21.5 million used for operating activities during the comparable six month period in 2013.  The decrease of $13.1 million is primarily driven by a reduction in NDA submission related costs and improved efficiency in organization and operations. The Company believes that its capital resources are adequate to fund operations through the first half of 2015.

Because Delcath’s business does not generate positive cash flow from operating activities, the Company will need to raise additional capital in order to fund its clinical development program or to fully commercialize the product. The Company continues to believe it will be able to raise additional capital in the event it is in its best interest to do so. The Company anticipates raising such additional capital by either borrowing money, selling shares of Delcath’s capital stock, or entering into strategic alliances with appropriate partners. To the extent additional capital is not available when needed, the Company may be forced to abandon some or all of its development and commercialization efforts, which would have a material adverse effect on the prospects of our business. Further, the Company’s assumptions relating to its cash requirements may differ materially from its actual requirements because of a number of factors, including significant unforeseen delays in the regulatory approval process, changes in the focus and direction of clinical trials, lower revenue and increased costs related to commercializing the product.

The Company has funded its operations through a combination of private placements of its securities, public offerings in 2000, 2003, 2009, 2010, 2011, 2012 and 2013, registered direct offerings in 2007 and 2009, an “at the market” equity offering program initiated in 2012, and a committed equity financing facility program initiated in 2012. For a detailed discussion of the Company’s various sales of securities and the “at the market” equity offering program see Note 7 to the Company’s interim condensed consolidated financial statements contained in this Quarterly Report on Form 10-Q.

In March 2013, the Company entered into a sales agreement (the “March 2013 Sales Agreement”) with Cowen and Company, LLC to sell shares of the Company’s common stock, par value $.01 per share, having aggregate sales proceeds of $50.0 million, from time to time, through an “at the market” equity offering program under which Cowen and Company, LLC will act as sales agent. During the six months ended June 30, 2014, the Company sold approximately 1.0 million shares of its common stock under the March 2013 Sales Agreement with Cowen and Company, LLC for proceeds of approximately $4.4 million, with net cash proceeds after related expenses of approximately $4.4 million. The shares were issued pursuant to registration statement on Form S-3 (333-187230). The net proceeds will be used for general corporate purposes, including, but not limited to, commercialization of our products, obtaining regulatory approvals, funding of our clinical trials, capital expenditures and working capital. 

In December 2011, the Company filed a registration statement on Form S-3 with the SEC, which allowed the Company to offer and sell, from time to time in one or more offerings, up to $100 million of common stock, preferred stock, warrants, debt securities and stock purchase contracts as it deemed prudent or necessary to raise capital at a later date. The registration statement became effective on February 13, 2012. The Company used this registration statement for its May 2012 public offering detailed in Note 10 to the Company’s audited financial statements contained in the 2013 Annual Report on Form 10-K.  The Company subsequently filed a new shelf registration statement on Form S-3 (333-183675) with the SEC which became effective on October 9, 2012. This new shelf replaces the shelf registration filed in December 2011 and allows the Company to offer and sell, from time to time in one or more offerings, up to $100 million of common stock, preferred stock, warrants, debt securities and stock purchase contracts as it deems prudent or necessary to raise capital at a later date. The Company used this registration statement for its Common Stock Purchase Agreement with Terrapin Opportunity, L.P. detailed in Note 10 to the Company’s audited financial statements contained in the 2013 Annual Report on Form 10-K. As of June 30, 2014, Delcath had approximately $80.4 million available under this registration statement, of which approximately $4.9 million is reserved for the potential issuance of shares upon the exercise of warrants.
DELCATH SYSTEMS, INC.

The Company intends to use the net proceeds from any future offerings for general corporate purposes, including, but not limited to, funding of clinical trials, obtaining regulatory approvals, commercialization of its products, capital expenditures and working capital.

Application of Critical Accounting Policies
 
The Company’s financial statements have been prepared in accordance with generally accepted accounting principles in the United States of America (GAAP).  Certain accounting policies have a significant impact on amounts reported in the financial statements.  A summary of those significant accounting policies can be found in Note 3 to the Company’s audited financial statements contained in the 2013 Annual Report on Form 10-K.  During 2012, Delcath transitioned from a development stage company to a commercial organization.

The Company considers the valuation allowance for the deferred tax assets to be a significant accounting estimate.  In applying ASC 740 management estimates future taxable income from operations and tax planning strategies in determining if it is more likely than not that the Company will realize the benefits of its deferred tax assets.  Management believes the Company does not have any uncertain tax positions.

The Company has adopted the provisions of ASC 718, which establishes accounting for equity instruments exchanged for employee services. Under the provisions of ASC 718, share-based compensation is measured at the grant date, based upon the fair value of the award, and is recognized as an expense over the option holders’ requisite service period (generally the vesting period of the equity grant). The Company expenses its share-based compensation under the ratable method, which treats each vesting tranche as if it were an individual grant.

The Company has adopted the provisions of ASC 820, which defines fair value, establishes a framework for measuring fair value, and expands disclosures about fair value measurements.

ASC 820 emphasizes that fair value is a market-based measurement, not an entity-specific measurement. Therefore, a fair value measurement should be determined based on the assumptions that market participants would use in pricing the asset or liability. As a basis for considering market participant assumptions in fair value measurements, ASC 820 establishes a fair value hierarchy that distinguishes between market participant assumptions based on market data obtained from sources independent of the reporting entity (observable inputs that are classified within Levels 1 and 2 of the hierarchy) and the reporting entity’s own assumptions about market participant assumptions (unobservable inputs classified within Level 3 of the hierarchy).
 
Level 1 inputs utilize quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access. Level 2 inputs are inputs other than quoted prices included in Level 1 that are observable for the asset or liability, either directly or indirectly. Level 2 inputs may include quoted prices for similar assets and liabilities in active markets, as well as inputs that are observable for the asset or liability (other than quoted prices), such as interest rates, foreign exchange rates and yield curves that are observable at commonly quoted intervals. Level 3 inputs are unobservable inputs for the asset or liability which are typically based on an entity’s own assumptions, as there is little, if any, related market activity. In instances where the determination of the fair value measurement is based on inputs from different levels of the fair value hierarchy, the level in the fair value hierarchy within which the entire fair value measurement falls is based on the lowest level input that is significant to the fair value measurement in its entirety. The Company’s assessment of the significance of a particular input to the fair value measurement in its entirety requires judgment and considers factors specific to the asset or liability. See Note 8 to the Company’s Condensed Consolidated Financial Statements contained in this Quarterly Report on Form 10-Q for assets and liabilities the Company has evaluated under ASC 820.
DELCATH SYSTEMS, INC.
 
Item 3. Quantitative and Qualitative Disclosures about Market Risk

The Company may be minimally exposed to market risk through changes in market interest rates that could affect the interest earned on its cash balances.

The Company measures all derivatives, including certain derivatives embedded in contracts, at fair value and recognizes them on the balance sheet as an asset or a liability, depending on the Company’s rights and obligations under the applicable derivative contract.

In June 2009, the Company completed the sale of 0.1 million shares of its common stock and the issuance of warrants to purchase 0.1 million common shares (the “2009 Warrants”) pursuant to a subscription agreement with a single investor. The Company received proceeds of $3.0 million, with net cash proceeds after related expenses from this transaction of approximately $2.7 million. Of those proceeds, the Company allocated an estimated fair value of $2.2 million to the 2009 Warrants. As required by the 2009 Warrant agreement, the exercise price of the warrants was adjusted following the Company’s October 2013 sale of common stock and warrants. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. During the six months ended June 30, 2014, 35,000 2009 Warrants were exercised for net proceeds of approximately $0.1 million. The 2009 Warrants had a five-year term which expired on June 15, 2014. The remaining liability after warrant exercises was credited to pre-tax derivative instrument income.

In May 2012, the Company completed the sale of 1.0 million shares of its common stock and the issuance of warrants to purchase 0.3 million common shares (the “2012 Warrants”) pursuant to an underwriting agreement. The Company received proceeds of $21.5 million, with net cash proceeds after related expenses from this transaction of approximately $21.1 million. Of those proceeds, the Company allocated an estimated fair value of $3.4 million to the 2012 Warrants. As required by the 2012 Warrant agreement, the exercise price of the warrants was adjusted following the Company’s October 2013 sale of common stock and warrants. At June 30, 2014, the 2012 Warrants were exercisable at $2.56 per share with 0.3 million warrants outstanding. The 2012 Warrants have a three-year term. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. During the six months ended June 30, 2014, approximately 13,000 2012 Warrants were exercised for net proceeds of approximately $34,000.

In October 2013, the Company completed the sale of 1.3 million shares of its common stock and the issuance of warrants to purchase 0.6 million common shares (the “2013 Warrants”) pursuant to a placement agency agreement. The Company received proceeds of $7.5 million, with net cash proceeds after related expenses from this transaction of approximately $6.9 million. Of those proceeds, the Company allocated an estimated fair value of $1.9 million to the 2013 Warrants. The 2013 Warrants became exercisable on April 30, 2014 and at June 30, 2014, the 2013 Warrants were exercisable at $7.04 per share with 0.6 million warrants outstanding. The 2013 Warrants have a five-year term. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. There were no 2013 Warrants exercised during the six months ended June 30, 2014.

The $1.9 million in proceeds allocated to the 2013 Warrants, the $3.4 million in proceeds allocated to the 2012 Warrants and the $2.2 million in proceeds allocated to the 2009 Warrants are classified as derivative instrument liabilities that are subject to mark-to-market adjustment each period. As a result, for the three and six month periods ended June 30, 2014, the Company recorded pre-tax derivative instrument income of $1.3 million and $1.1 million, respectively. The resulting derivative instrument liabilities totaled $1.1 million at June 30, 2014. Management expects that the warrants outstanding at June 30, 2014 will either be exercised or expire worthless. The fair value of the Warrants at June 30, 2014 was determined by using an option pricing model assuming the following:
 
 
 
2013 Warrants
   
2012 Warrants
 
Expected volatility
   
94.18%
   
111.35%
 
Risk-free interest rates
1.34%
0.11%
Expected life (in years)
   
4.33
     
0.92
 

DELCATH SYSTEMS, INC.
 
Item 4.
Controls and Procedures

Evaluation of Disclosure Controls and Procedures
Delcath’s management, with the participation of its Interim Co-Chief Executive Officers, evaluated the effectiveness of the design and operation of its disclosure controls and procedures (as defined in Rule 13a-15(e) or 15d-15(e) of the Exchange Act. Based on that evaluation, the Company’s Interim Co-Chief Executive Officers concluded that Delcath’s disclosure controls and procedures as of June 30, 2014 (the end of the period covered by this Quarterly Report on Form 10-Q), have been designed and are functioning effectively to provide reasonable assurance that the information required to be disclosed by us in the Company’s reports filed or submitted under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms, and that such information is accumulated and communicated to management, including the Company’s Interim Co-Chief Executive Officers, as appropriate to allow timely decisions regarding required disclosure.

Changes in Internal Controls
There was no change in our internal control over financial reporting that occurred during the quarter ended June 30, 2014 that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.
DELCATH SYSTEMS, INC.
 
PART II: OTHER INFORMATION

Item 1.
Legal Proceedings

In re Delcath Systems, Inc. Securities Litigation, United States District Court for the Southern District of New York (Case No. 13-cv-3116)

On May 8, 2013, a purported stockholder of the Company filed a putative class action complaint in the United States District Court for the Southern District of New York, captioned Bryan Green, individually and on behalf of all others similar situated, v. Delcath Systems, Inc., et al. (“Green”), Case No. 1:13-cv-03116-LGS.  On June 14, 2013, a substantially similar complaint was filed in the United States District Court for the Southern District of New York, captioned Joseph Connico, individually and on behalf of all others similarly situated, v. Delcath Systems, Inc., et al. (“Connico”), Case No. 1:13-cv-04131-LGS.

At a hearing on August 2, 2013, the Court consolidated the Green and Connico actions under the caption In re Delcath Systems, Inc. Securities Litigation, No. 13-cv-3116, appointed Lead Plaintiff, Delcath Investor Group, and approved Pomerantz Grossman Hufford Dahlstrom & Gross LLP as Lead Plaintiff’s choice of counsel.

On September 18, 2013, Lead Plaintiff filed a consolidated amended complaint, naming the Company and Eamonn P. Hobbs as defendants (the “Defendants”).  The consolidated amended complaint asserts that Defendants violated Sections 10(b) and 20(a) of the Securities Exchange Act of 1934 by allegedly making false and misleading statements or omissions regarding the Company’s New Drug Application for its Melblez Kit (Melblez (melphalan) for Injection for use with the Delcath Hepatic Delivery System), for the treatment of patients with unresectable metastatic ocular melanoma in the liver.  The putative class period alleged in the amended complaint is April 21, 2010 through and including September 13, 2013. Lead Plaintiff seeks compensatory damages, equitable relief, and reasonable attorneys’ fees, expert fees and other costs.  On October 31, 2013, Defendants filed their motion to dismiss, which was subsequently denied on June 27, 2014.  On July 25, 2014, Defendants filed their respective answers to Lead Plaintiff’s consolidated amended complaint.  On July 29, 2014, the Court held a scheduling conference setting forth a case management plan.  The parties are proceeding with discovery.     
 
The Company believes that the In re Delcath Systems, Inc. Securities Litigation action lacks merit and intends to defend the case vigorously.

In re Delcath Systems, Inc. Derivative Shareholder Litigation, United States District Court for the Southern District of New York (Lead Case No. 1:13-cv-03494-LGS)

On May 23, 2013, purported stockholders of the Company filed a shareholder derivative lawsuit in the United States District Court for the Southern District of New York, captioned Vincent J. Orlando and Carol Orlando, derivatively on behalf of Delcath Systems, Inc. v. Harold S. Koplewicz, et al. (“Orlando”), Case No. 1:13-cv-03494-LGS.  On June 11, 2013, a substantially similar complaint was filed in the United States District Court for the Southern District of New York, captioned Howard Warsett, derivatively on behalf of Delcath Systems, Inc. v. Harold S. Koplewicz, et al. (“Warsett”), Case No. 1:13-cv-04002-LGS.  On July 19, 2013, another substantially similar complaint was filed in the United States District Court for the Southern District of New York, captioned Patricia Griesi, derivative on behalf of nominal defendant Delcath Systems, Inc. v. Harold S. Koplewicz, et al. (“Griesi”), Case No. 13 cv 5024.  In all three cases, Harold S. Koplewicz, Laura A. Brege, Tasos G. Konidaris, Eamonn P. Hobbs, Douglas G. Watson, Laura A. Philips, Roger G. Stoll, and Gabriel Leung were named as defendants (the“Individual Defendants”), and the Company was named as a nominal defendant.

All three complaints assert claims for breach of fiduciary duty for disseminating false and misleading information, breach of fiduciary duty for failing to properly oversee and manage the company, and gross mismanagement for making false and misleading statements or failing to disclose material information regarding (i) the Company’s New Drug Application for its Melblez Kit (Melblez (melphalan) for Injection for use with the Delcath Hepatic Delivery System), for the treatment of patients with unresectable metastatic ocular melanoma, and (ii) the status of the Company’s manufacturing facilities.  In addition, the Orlando complaint further asserts claims for contribution and indemnification, abuse of control, and waste of corporate assets, while the Warsett complaint asserts an additional claim for unjust enrichment.  The Griesi complaint also asserts additional claims for breach of fiduciary duties for failing to maintain internal controls, unjust enrichment, abuse of control, and violations of Section 14(a) of the Securities Exchange Act of 1934.  The relevant time period alleged in the Orlando action is April 21, 2010 through the present, and the relevant time period alleged in the Warsett action is April 10, 2010 through the present.  The relevant time period alleged in Griesi is April 21, 2010 through May 2, 2013.  The Orlando, Warsett, and Griesi plaintiffs seek damages as well as reasonable costs and attorneys’ fees. The Griesi plaintiffs also seek corporate governance reforms and improvements and restitution.
DELCATH SYSTEMS, INC.
 
On June 25, 2013, the Court consolidated the Orlando and Warsett actions with the caption In re Delcath Systems, Inc. Derivative Shareholder Litigation, Lead Case No. 1:13-cv-03494-LGS (“Consolidated Derivative Case”).  On August 1, 2013, the Court consolidated the Griesi action under the caption In re Delcath Systems, Inc. Derivative Shareholder Litigation, Lead Case No. 1:13-cv-03494-LGS.  At a hearing on August 2, 2013, the Court entered an order approving Federman & Sherwood as lead counsel.  The Court stayed the Consolidated Derivative Case, pending resolution of an anticipated motion to dismiss in In re Delcath Systems, Inc. Securities Litigation, United States District Court for the Southern District of New York, No. 13-cv-3116.

Plaintiffs anticipate filing an amended complaint on or before September 12, 2014, to which Defendants anticipate filing a motion to dismiss.

The defendants in the Consolidated Derivative Case deny any wrongdoing, believe the claims are baseless, and will defend accordingly.

Howard D. Weinstein, derivatively on behalf of Delcath Systems, Inc. v. Harold S. Koplewicz, et al., Supreme Court of the State of New York County of New York (Case No. 652030/2013)

On June 7, 2013, a purported stockholder of the Company filed a shareholder derivative lawsuit in the Supreme Court of the State of New York County of New York, captioned Howard D. Weinstein, derivatively on behalf of Delcath Systems, Inc. v. Harold S. Koplewicz, et al., (“Weinstein”) Case No. 652030/2013.  The action named Harold S. Koplewicz, Laura A. Brege, Tasos G. Konidaris, Eamonn P. Hobbs, Douglas G. Watson, Laura A. Philips, Roger G. Stoll, and Gabriel Leung as individual defendants (the “Individual Defendants”), as well as the Company, as a nominal defendant.

The complaint asserts claims for breach of fiduciary duty for disseminating false and misleading information, breach of fiduciary duty for failing to properly oversee and manage the company, gross mismanagement, contribution and indemnification, abuse of control, and waste of corporate assets in connection with allegations that the Individual Defendants made false and misleading statements or failed to disclose material information regarding (i) the Company’s New Drug Application for its Melblez Kit (Melblez (melphalan) for Injection for use with the Delcath Hepatic Delivery System), for the treatment of patients with unresectable metastatic ocular melanoma, and (ii) the status of the Company’s manufacturing facilities.  The relevant time period alleged is April 21, 2010 through the present.  The plaintiff seeks damages, as well as reasonable costs and attorneys’ fees.

In July 2014, the parties in the Weinstein matter agreed to stipulate to stay the proceeding until the federal district court rules on the anticipated motion to dismiss in In re Delcath Systems, Inc. Derivative Shareholder Litigation, United States District Court for the Southern District of New York (Lead Case No. 1:13-cv-03494-LGS)
 
The defendants in the Weinstein matter deny any wrongdoing, believe the claims are baseless, and will defend accordingly.
DELCATH SYSTEMS, INC.
Item1A.
Risk Factors
 
Delcath’s 2013 Annual Report on Form 10-K, in Part 1 – Item 1A. "Risk Factors," contains a detailed discussion of factors that could materially adversely affect our business, operating results and/or financial condition.  There have been no material changes in these risk factors since such disclosure.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds

Not Applicable.

Item 3. Defaults upon Senior Securities
 
Not Applicable.

Item 4. Mine Safety Disclosures

Not Applicable.

Item 5. Other Information

Not Applicable.

DELCATH SYSTEMS, INC.
 
Item 6. Exhibits
 
Exhibit No.
 
Description
 
 
 
10.1 (1)  Sublease between Delcath Systems, Inc. and SLG 810 Seventh Lessee LLC, dated May 22, 2014
 
10.2 (2)  Agreement of Lease dated February 5, 2010 and Lease Modification, Extension and Additional Space Agreement dated September 27, 2010
 
31.1
**
Certification by Co-Principal executive officer Pursuant to Rule 13a 14.
 
 
 
31.2
**
Certification by Co-Principal executive officer Pursuant to Rule 13a 14.
 
 
 
31.3
**
Certification by Principal financial officer Pursuant to Rule 13a 14.
 
 
 
32.1
***
Certification of Interim Co-Chief Executive Officer Pursuant to 18 U.S.C. Section 1350 as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
32.2
***
Certification of Interim Co-Chief Executive Officer Pursuant to 18 U.S.C. Section 1350 as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
32.3
*** 
Certification of Principal financial officer Pursuant to 18 U.S.C. Section 1350 as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
101.INS
 
XBRL Instance Document
 
 
 
101.SCH
 
XBRL Taxonomy Extension Schema Document
 
 
 
101.CAL
 
XBRL Taxonomy Extension Calculation Linkbase Document
 
 
 
101.DEF
 
XBRL Taxonomy Extension Definition Linkbase Document
 
 
 
101.LAB
 
XBRL Taxonomy Extension Label Linkbase Document
 
 
 
101.PRE
 
XBRL Taxonomy Extension Presentation Linkbase Document

** Filed herewith.

*** Furnished herewith.
 
(1)
Filed as an Exhibit to our Current Report on Form 8-K filed with the SEC on May 28, 2014 and incorporated herein by reference.
 
(2)
Filed as an Exhibit to our Quarterly Report on Form 10-Q for the quarter ended March 31, 2010, filed with the SEC on May 5, 2010 and incorporated herein by reference.
DELCATH SYSTEMS, INC.
 
SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

August 6, 2014
DELCATH SYSTEMS, INC.
 
 
 
(Registrant)
 
 
 
 
 
 
 
/s/Graham G. Miao
 
/s/Jennifer K. Simpson
 
Graham G. Miao
 
Jennifer K. Simpson
 
Interim Co-President and
 
Interim Co-President and
 
Co-Chief Executive Officer,
 
Co-Chief Executive Officer,
 
Chief Financial Officer
 
Global Head of Business Operations
 
(Co-Principal executive officer and
 
(Co-Principal executive officer)
 
Principal financial officer)
 
 
DELCATH SYSTEMS, INC.
 
Exhibit Index

Exhibit No.
 
Description
 
 
 
10.1 (1)  Sublease between Delcath Systems, Inc. and SLG 810 Seventh Lessee LLC, dated May 22, 2014
 
10.2 (2)  Agreement of Lease dated February 5, 2010 and Lease Modification, Extension and Additional Space Agreement dated September 27, 2010
 
**
Certification by Co-Principal executive officer Pursuant to Rule 13a 14.
 
 
 
**
Certification by Co-Principal executive officer Pursuant to Rule 13a 14.
 
 
 
**
Certification by Principal financial officer Pursuant to Rule 13a 14.
 
 
 
***
Certification of Interim Co-Chief Executive Officer Pursuant to 18 U.S.C. Section 1350 as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
***
Certification of Interim Co-Chief Executive Officer Pursuant to 18 U.S.C. Section 1350 as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
*** 
Certification of Principal financial officer Pursuant to 18 U.S.C. Section 1350 as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
101.INS
 
XBRL Instance Document
 
 
 
101.SCH
 
XBRL Taxonomy Extension Schema Document
 
 
 
101.CAL
 
XBRL Taxonomy Extension Calculation Linkbase Document
 
 
 
101.DEF
 
XBRL Taxonomy Extension Definition Linkbase Document
 
 
 
101.LAB
 
XBRL Taxonomy Extension Label Linkbase Document
 
 
 
101.PRE
 
XBRL Taxonomy Extension Presentation Linkbase Document

** Filed herewith.

*** Furnished herewith.
 
(1)
Filed as an Exhibit to our Current Report on Form 8-K filed with the SEC on May 28, 2014 and incorporated herein by reference.
 
(2)
Filed as an Exhibit to our Quarterly Report on Form 10-Q for the quarter ended March 31, 2010, filed with the SEC on May 5, 2010 and incorporated herein by reference.
 
 
34

EX-31.1 2 ex31_1.htm EXHIBIT 31.1

DELCATH SYSTEMS, INC.
 
EXHIBIT 31.1
Certification
of Principal Executive Officer
Pursuant to Rule 13a-14(a) and 15d-14(a) of the Exchange Act

I, Graham G. Miao, certify that:

1) I have reviewed this Quarterly Report on Form 10-Q of Delcath Systems, Inc;

2) Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3) Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4) The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5) The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

August 6, 2014
 
 
 
/s/Graham G. Miao
 
 
Graham G. Miao
 
 
Interim Co-President and Co-Chief Executive Officer,
 
 
Chief Financial Officer
 
 
(Co-Principal executive officer)
 
 

EX-31.2 3 ex31_2.htm EXHIBIT 31.2
DELCATH SYSTEMS, INC.
 
EXHIBIT 31.2
 
Certification
of Principal Executive Officer
Pursuant to Rule 13a-14(a) and 15d-14(a) of the Exchange Act
 
I, Jennifer K. Simpson, certify that:

1) I have reviewed this Quarterly Report on Form 10-Q of Delcath Systems, Inc;

2) Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3) Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4) The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5) The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

August 6, 2014
 
 
 
/s/Jennifer K. Simpson
 
 
Jennifer K. Simpson
 
 
Interim Co-President and Co-Chief Executive Officer,
 
 
Global Head of Business Operations
 
 
(Co-Principal executive officer)
 
 

EX-31.3 4 ex31_3.htm EXHIBIT 31.3

DELCATH SYSTEMS, INC.

EXHIBIT 31.3
Certification
of Principal Financial Officer
Pursuant to Rule 13a-14(a) and 15d-14(a) of the Exchange Act

I, Graham G. Miao, certify that:

1) I have reviewed this Quarterly Report on Form 10-Q of Delcath Systems, Inc;

2) Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3) Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4) The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5) The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

August 6, 2014
 
 
 
/s/Graham G. Miao
 
 
Graham G. Miao
 
 
Interim Co-President and Co-Chief Executive Officer,
 
 
Chief Financial Officer
 
 
(Principal financial officer)
 
 

EX-32.1 5 ex32_1.htm EXHIBIT 32.1

DELCATH SYSTEMS, INC.
 
 EXHIBIT 32.1

Certification Pursuant to
18 U.S.C. Section 1350,
as Adopted Pursuant to
Section 906 of the Sarbanes –Oxley Act of 2002

In connection with the Quarterly Report of DELCATH SYSTEMS, INC. (the “Company”) on Form 10-Q for the fiscal quarter ended June 30, 2014, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Graham G. Miao, the Interim Co-President and Co-Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that, to my knowledge:

(1)          The Report fully complies with the requirements of section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934, as amended; and

(2)          The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

August 6, 2014
 
 
 
/s/Graham G. Miao
 
 
Graham G. Miao
 
 
Interim Co-President and Co-Chief Executive Officer,
 
 
Chief Financial Officer
 
 
(Co-Principal executive officer)
 
 

EX-32.2 6 ex32_2.htm EXHIBIT 32.2

DELCATH SYSTEMS, INC.
 
EXHIBIT 32.2

Certification Pursuant to
18 U.S.C. Section 1350,
as Adopted Pursuant to
Section 906 of the Sarbanes –Oxley Act of 2002

In connection with the Quarterly Report of DELCATH SYSTEMS, INC. (the “Company”) on Form 10-Q for the fiscal quarter ended June 6, 2014, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Jennifer K. Simpson, the Interim Co-President and Co-Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that, to my knowledge:

(1)       The Report fully complies with the requirements of section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934, as amended; and

(2)        The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

August 6, 2014
 
 
 
/s/Jennifer K. Simpson
 
 
Jennifer K. Simpson
 
 
Interim Co-President and Co-Chief Executive Officer,
 
 
Global Head of Business Operations
 
 
(Co-Principal executive officer)
 
 

EX-32.3 7 ex32_3.htm EXHIBIT 32.3

DELCATH SYSTEMS, INC.
 
EXHIBIT 32.3

Certification Pursuant to
18 U.S.C. Section 1350,
as Adopted Pursuant to
Section 906 of the Sarbanes –Oxley Act of 2002

In connection with the Quarterly Report of DELCATH SYSTEMS, INC. (the “Company”) on Form 10-Q for the fiscal quarter ended June 30, 2014, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Graham G. Miao, the Interim Co-President and Co-Chief Executive Officer, Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that, to my knowledge:

(1)          The report fully complies with the requirements of section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934, as amended; and

(2)          The information contained in the report fairly presents, in all material respects, the financial condition and results of operations of the Company.

August 6, 2014
 
 
 
/s/Graham G. Miao
 
 
Graham G. Miao
 
 
Interim Co-President and Co-Chief Executive Officer,
 
 
Chief Financial Officer
 
 
(Principal financial officer)
 

 

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There are six inputs: closing price of Delcath stock on the day of evaluation; the exercise price of the warrants; the remaining term of the warrants; the volatility of Delcath&#8217;s stock over that term; annual rate of dividends; and the riskless rate of return. Of those inputs, the exercise price of the warrants and the remaining term are readily observable in the warrant agreements. The annual rate of dividends is based on the Company&#8217;s historical practice of not granting dividends. The closing price of Delcath stock would fall under Level 1 of the fair-value hierarchy as it is a quoted price in an active market (ASC 820-10). The riskless rate of return is a Level 2 input as defined in ASC 820-10, while the historical volatility is a Level 3 input as defined in ASC 820. 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(&#8220;Delcath&#8221; or the &#8220;Company&#8221;) for the three and six months ended June 30, 2014 and 2013 should be read in conjunction with the Consolidated Financial Statements included in the Company&#8217;s Annual Report on Form 10-K (&#8220;Annual Report&#8221;) for the year ended December 31, 2013, which has been filed with the Securities Exchange Commission (&#8220;SEC&#8221;) and can also be found on the Company&#8217;s website (www.delcath.com). In these notes the terms &#8220;us&#8221;, &#8220;we&#8221; or &#8220;our&#8221; refer to Delcath and its consolidated subsidiaries.</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: justify;">On April 8, 2014, the Company effected a one-for-sixteen (1:16) reverse stock split. Refer to Note 7 <font style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; font-style: italic;">Stockholders&#8217; Equity </font>of these Condensed Consolidated Financial Statements for further information.</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; font-weight: bold; font-style: italic; text-align: justify;">Description of Business</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: justify;">Delcath Systems, Inc. is a specialty pharmaceutical and medical device company focused on oncology. Our proprietary product&#8212;Melphalan Hydrochloride for Injection for use with the Delcath Hepatic Delivery System (Melphalan HDS)&#8212;is designed to administer high dose chemotherapy to the liver, while controlling the systemic exposure to those agents. 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To the extent additional capital is not available when needed, the Company may be forced to abandon some or all of its development and commercialization efforts, which would have a material adverse effect on the prospects of the business.&#160; Operations of the Company are subject to certain risks and uncertainties, including, among others, uncertainties and risks related to product development; regulatory approvals; technology; patents and proprietary rights; comprehensive government regulations; limited commercial manufacturing; marketing and sales experience; and dependence on key personnel.</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; font-weight: bold; font-style: italic; text-align: justify; margin-right: 0.1pt;">Basis of Presentation</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: justify;">These interim Condensed Consolidated Financial Statements are unaudited and were prepared by the Company in accordance with generally accepted accounting principles in the United States of America (GAAP) and with the SEC&#8217;s instructions to Form 10-Q and Article 10 of Regulation S-X. 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font-family: ''Times New Roman'', Times, serif;">(18,328</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">)</div></td></tr><tr><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 42%; background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: left; margin-left: 7.2pt; text-indent: -7.2pt;">Adjustment for gain on warrant derivative liability</div></td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: right; width: 9%; background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">(356</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%; background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">)</div></td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: right; width: 9%; background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">&#8212;</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: right; width: 9%; background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">(363</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%; background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">)</div></td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: right; width: 9%; background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">&#8212;</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td></tr><tr><td valign="bottom" style="vertical-align: bottom; padding-bottom: 4px; width: 42%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: left; margin-left: 7.2pt; text-indent: -7.2pt;">Net loss &#8211; diluted</div></td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 4px; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 4px double; text-align: left; width: 1%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">$</div></td><td valign="bottom" style="vertical-align: bottom; 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text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td></tr><tr><td valign="bottom" style="vertical-align: bottom; width: 42%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: left; margin-left: 7.2pt; text-indent: -7.2pt;">Weighted average shares outstanding &#8211; basic</div></td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">9,426,169</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">6,023,785</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; 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background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">99,594</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 2px solid; text-align: right; width: 9%; background-color: #ffffff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">&#8212;</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td></tr><tr><td valign="bottom" style="vertical-align: bottom; 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font-family: ''Times New Roman'', Times, serif;">9,462,717</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 4px; text-align: left; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 4px; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 4px double; text-align: left; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; border-bottom: #000000 4px double; text-align: right; width: 9%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">5,683,380</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 4px; text-align: left; width: 1%; background-color: #cceeff;">&#160;</td></tr><tr><td valign="bottom" style="vertical-align: bottom; width: 42%; background-color: #ffffff;"><div>&#160;</div></td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td></tr><tr><td valign="bottom" style="vertical-align: bottom; width: 42%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: left; margin-left: 7.2pt; text-indent: -7.2pt;">Net loss per share &#8211; basic</div></td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">$</div></td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">(0.49</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif;">)</div></td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #cceeff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #cceeff;"><div style="font-size: 10pt; 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font-size: 10pt;"><div><div style="text-align: justify;"><table cellpadding="0" cellspacing="0" class="DSPFListTable" style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; width: 100%;"><tr><td style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; vertical-align: top; font-weight: bold; width: 27pt; align: right;">(7)</td><td style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; vertical-align: top; font-weight: bold; text-align: justify; width: auto;">Stockholders&#8217; Equity</td></tr></table></div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; font-weight: bold; font-style: italic; text-align: justify;">Stock Issuances</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; font-style: italic; text-align: justify;">Reverse Stock Split</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: justify;">On February 24, 2014, shareholders of the Company approved, through a shareholder vote, an amendment to the Company&#8217;s Amended and Restated Certificate of Incorporation authorizing the Board of Directors to effect a reverse stock split of Delcath&#8217;s common stock. The reverse stock split became effective on April 8, 2014 at which time Delcath&#8217;s common stock began trading on the NASDAQ Stock Exchange on a one-for-sixteen (1:16) split-adjusted basis. All owners of record as of the close of the NASDAQ market on April 8, 2014 received one issued and outstanding share of Delcath common stock in exchange for sixteen issued and outstanding shares of Delcath common stock. No fractional shares were issued in connection with the reverse stock split. All fractional shares created by the one-for-sixteen exchange were rounded up to the next whole share. The reverse stock split had no impact on the number of common shares authorized or the par value per share of Delcath common stock, which remain 170,000,000 and $0.01, respectively. All current and prior period amounts related to shares, share prices and earnings per share, presented in these Condensed Consolidated Financial Statements and the accompanying Notes, have been restated to give retrospective presentation for the reverse stock split.</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; font-style: italic; text-align: justify;">At-the-Market (&#8220;ATM&#8221;) Programs</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: justify;">In December 2011, the Company entered into an agreement with Cowen and Company, LLC (&#8220;Cowen&#8221;) to sell shares of its common stock, par value $.01 per share, from time to time, through an ATM equity offering program having aggregate sales proceeds of $39.8 million, under which Cowen would act as sales agent. During the first quarter of 2013, the Company sold approximately 14.2 million shares of its common stock under this ATM program for proceeds of approximately $20.9 million, with net cash proceeds after related expenses of approximately $20.8 million, and successfully completed the program. As of March 31, 2013, there were no shares of common stock of the Company remaining for sale under this ATM program.</div></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: justify;">&#160;</div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: justify;">In March 2013, the Company entered into a new agreement with Cowen to sell shares of the Company&#8217;s common stock, par value $.01 per share, from time to time, through an ATM equity offering program having aggregate sales proceeds of $50.0 million, under which Cowen will act as sales agent. During the year ended December 31, 2013, the Company sold approximately 1.0 million shares of its common stock under this ATM program for proceeds of approximately $5.0 million, with net cash proceeds after related expenses of approximately $4.8 million. During the first quarter of 2014 the Company sold an additional 1.0 million shares of its common stock under this ATM program for proceeds of approximately $4.4 million, with net cash proceeds after related expenses of approximately $4.4 million. The shares were issued pursuant to an effective registration statement on Form S-3 (333-187230). The net proceeds will be used for general corporate purposes, including, but not limited to, commercialization of our products, obtaining regulatory approvals, funding of our clinical trials, capital expenditures and working capital. There were no shares of common stock sold under the ATM program during the second quarter of 2014. 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As a result, there was approximately $23.9 million available under this CEFF program as of June 30, 2014. The shares were issued pursuant to an effective registration statement on Form S-3 (333-183675). 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Of those proceeds, the Company allocated an estimated fair value of $2.2 million to the 2009 Warrants. As required by the 2009 Warrant agreement, the exercise price of the warrants was adjusted following the Company&#8217;s October 2013 sale of common stock and warrants. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. During the six months ended June 30, 2014, 35,000 2009 Warrants were exercised for net proceeds of approximately $0.1 million. The 2009 Warrants had a five-year term which expired on June 15, 2014. 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The 2012 Warrants have a three-year term. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. During the six months ended June 30, 2014, approximately 13,000 2012 Warrants were exercised for net proceeds of approximately $34,000.</div><div><br /></div><div style="font-size: 10pt; font-family: ''Times New Roman'', Times, serif; text-align: justify;">In October 2013, the Company completed the sale of 1.3 million shares of its common stock and the issuance of warrants to purchase 0.6 million common shares (the &#8220;2013 Warrants&#8221;) pursuant to a placement agency agreement. The Company received proceeds of $7.5 million, with net cash proceeds after related expenses from this transaction of approximately $6.9 million. Of those proceeds, the Company allocated an estimated fair value of $1.9 million to the 2013 Warrants. 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Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Short term portion of lease restructuring Short-term portion of lease restructuring Restricted Stock Activity [Abstract] Stock Option Activity under the Plans [Abstract] Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Exercise Price per Share [Roll Forward] Stock Options, Exercise Price per Share [Roll Forward] Exercise price at which grantees can acquire the shares reserved for issuance under the stock option plan. Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Exercise Price per Share Outstanding at June 30, 2014 (in dollars per share) Outstanding at December 31, 2013 (in dollars per share) Exercise price at which grantees could have acquired the underlying shares with respect to stock options that were terminated. Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Exercise Price per Share Forfeited (in dollars per share) Exercise price at which grantees can acquire the shares reserved for issuance on stock options awarded. Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Exercise Price per Share Granted (in dollars per share) Exercise price at which grantees could have acquired the underlying shares with respect to stock options that were expired. Share Based Compensation Arrangements By Share Based Payment Award Options Expired In Period Exercise Price Per Share Expired (in dollars per share) EX-101.PRE 13 dcth-20140630_pre.xml XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE EXCEL 14 Financial_Report.xlsx IDEA: XBRL DOCUMENT begin 644 Financial_Report.xlsx M4$L#!!0`!@`(````(0!,"'?^XP$``$,7```3``@"6T-O;G1E;G1?5'EP97-= M+GAM;""B!`(HH``"```````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M```````````````````````````````````````````````````````````` M``````````````````````````````````````#,F,U.XS`4A?=(O$/D+6I< M._S-J"D+?I:`!#R`)[YMHB:V91MHWQXG!810IZB:2G,VC=K8]WRUE$_*F5PL MNS9[(1\::THF\C'+R%16-V9>LJ?'F]$YRT)41JO6&BK9B@*[F!X>3!Y7CD*6 M=IM0LCI&]YOS4-74J9!;1R;=F5G?J9B^^CEWJEJH.7$Y'I_RRII()HYB/X-- M)U!]WUTZ&M]HRNZ5C[>J2QA\V?)7ZQ=_K%WDVX=LH+2S65.1 MMM5SETX@#\Z3TJ$FBEV;#]>\4XWYX-Z2/RP.?+B(/8/T_V\8O".'!.$H0#B. 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Stockholders Equity (Details) (USD $)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 1 Months Ended 6 Months Ended 1 Months Ended 6 Months Ended 1 Months Ended 6 Months Ended 3 Months Ended 12 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended
Oct. 31, 2013
May 31, 2012
Jun. 30, 2009
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Dec. 31, 2013
Jun. 30, 2014
Maximum [Member]
Jun. 30, 2014
2004 Stock Incentive Plan [Member]
Jun. 30, 2014
2009 Stock Incentive Plan [Member]
Jun. 30, 2014
Stock Options [Member]
Jun. 30, 2013
Stock Options [Member]
Jun. 30, 2014
Stock Options [Member]
Jun. 30, 2013
Stock Options [Member]
Jun. 30, 2014
Restricted Stock [Member]
Jun. 30, 2013
Restricted Stock [Member]
Jun. 30, 2014
Restricted Stock [Member]
Jun. 30, 2013
Restricted Stock [Member]
May 31, 2012
2012 Warrants [Member]
Jun. 30, 2014
2012 Warrants [Member]
Jun. 30, 2009
2009 Warrants [Member]
Jun. 30, 2014
2009 Warrants [Member]
Oct. 31, 2013
2013 Warrants [Member]
Jun. 30, 2014
2013 Warrants [Member]
Mar. 31, 2014
Sales Agreement March 2013 [Member]
Cowen and Company, LLC [Member]
Dec. 31, 2013
Sales Agreement March 2013 [Member]
Cowen and Company, LLC [Member]
Jun. 30, 2014
Sales Agreement March 2013 [Member]
Cowen and Company, LLC [Member]
Jun. 30, 2014
CEFF [Member]
Terrapin Opportunity, L.P. [Member]
Mar. 31, 2013
Sales Agreement December 2011 [Member]
Cowen and Company, LLC [Member]
Jun. 30, 2013
Sales Agreement December 2011 [Member]
Cowen and Company, LLC [Member]
Dec. 31, 2013
Sales Agreement December 2011 [Member]
Cowen and Company, LLC [Member]
Stock Issuances [Abstract]                                                                
Reverse Stock Split Ratio       one-for- sixteen (1:16) one-for- sixteen (1:16)   one-for- sixteen (1:16) one-for- sixteen (1:16) one-for- sixteen (1:16)                                              
Common stock, shares authorized (in shares)       170,000,000   170,000,000   170,000,000                                                
Common stock, par value (in dollars per share)       $ 0.01   $ 0.01   $ 0.01                                                
Common stock, par value under sales agreement (in dollars per share)                                                       $ 0.01       $ 0.01
Proceeds from issuance of common stock                                                   $ 4,400,000 $ 5,000,000   $ 11,100,000   $ 20,900,000  
Proceeds of common stock issued, net of related expenses                                                   4,400,000 4,800,000   10,800,000   20,800,000  
Common stock sold through the program (in shares) 1,300,000 1,000,000 100,000                                             1,000,000 1,000,000   500,000 14,200,000    
Aggregate proceeds from sale of common stock under equity offering program, maximum                                                       50,000,000       39,800,000
Aggregate proceeds from sale of common stock under equity offering program, remaining                                                       40,400,000        
Amount to be purchased by party under agreement                                                         35,000,000      
Term of purchase agreement                                                         24 months      
Amount Available Under Committed Equity Financing Facility                                                         23,900,000      
Warrant [Abstract]                                                                
Warrants issued (in shares)                                       300,000   100,000   600,000                
Proceeds from issuance of private placement 7,500,000 21,500,000 3,000,000                                                          
Net proceeds from issuance of private placement 6,900,000 21,100,000 2,700,000                                                          
Estimated fair value allocated to warrants issued                                       3,400,000   2,200,000   1,900,000                
Warrants exercisable per share price (in dollars per share)                                         $ 2.56       $ 7.04              
Number of warrants outstanding (in shares)                                         260,000                      
Term period for warrants                                         3 years   5 years   5 years              
Warrants Exercised (in shares)                                         13,000   35,000                  
Net proceeds from exercise of warrants                                         34,000   100,000                  
Stock Incentive Plans [Abstract]                                                                
Shares reserved for the issuance (in shares)                   187,500 406,250                                          
Maximum term of options                           10 years                                    
Recognized compensation expense           257,000 571,000         100,000 100,000 300,000 600,000                                  
Restricted stock compensation expense           $ 60,000 $ 241,000                 $ 20,000 $ 100,000 $ 60,000 $ 200,000                          

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Stockholders Equity (Tables)
6 Months Ended
Jun. 30, 2014
Stockholders Equity [Abstract]  
Stock option activity
A stock option grant allows the holder of the option to purchase a share of the Company’s common stock in the future at a stated price. Options granted under the Plans vest as determined by the Company’s Compensation and Stock Option Committee and expire over varying terms, but not more than ten years from the date of grant. Stock option activity for the six months ended June 30, 2014 is as follows:
 
 
 
Stock Option Activity under the Plans
 
 
 
Stock
Options
  
Exercise
Price
per Share
  
Weighted
Average
Exercise
Price
  
Weighted
Average
Remaining
Life
(Years)
 
Outstanding at December 31, 2013
  
252,158
  
$
4.80 — $248.64
  
$
57.90
   
7.36
 
Granted
  
   
   
     
Forfeited
  
(52,303
)
 
$
5.92 — $248.64
   
75.99
     
Expired
  
(625
)
 
$
58.56 — $58.56
   
58.56
     
Outstanding at June 30, 2014
  
199,230
  
$
4.80 — $248.64
  
$
53.16
   
7.08
 
Assumptions used to determine the fair value of stock options
There were no options granted during the six months ended June 30, 2014. The estimated fair value of each option award granted during the six month period ended June 30, 2013 was determined on the date of grant using an option pricing model with the following assumptions:
 
 
 
Six months ended
June 30, 2013
 
Dividend yield
 
None
 
Expected volatility
  
86.16% — 93.68%
Weighted average volatility
  
86.21%
 
Risk-free interest rates
  
0.99% — 1.36%
 
Expected life (in years)
  
6.8
 
Restricted stock activity
Restricted stock activity for the six months ended June 30, 2014 is as follows:
 
 
 
Restricted Stock Activity
under the Plans
 
 
 
Restricted
Stock
  
Weighted Average
Grant Date
Fair Value
 
Non-vested at December 31, 2013
  
20,347
  
$
16.84
 
Granted
  
   
 
Vested
  
(17,233
)
  
12.70
 
Forfeited
  
(393
)
  
38.24
 
Non-vested at June 30, 2014
  
2,721
  
$
39.98
 
XML 18 R9.htm IDEA: XBRL DOCUMENT v2.4.0.8
Prepaid Expenses and Other Current Assets
6 Months Ended
Jun. 30, 2014
Prepaid Expenses and Other Current Assets [Abstract]  
Prepaid Expenses and Other Current Assets
(3)Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consist of the following:

(in thousands)
 
June 30,
2014
  
December 31,
2013
 
Kits for clinical use
 
$
327
  
$
287
 
Insurance premiums
  
322
   
407
 
Professional fees
  
27
   
377
 
Income tax credits receivable
  
18
   
326
 
Other1
  
158
   
314
 
Total prepaid expenses and other current assets
 
$
852
  
$
1,711
 
 
1 Other consists of various prepaid expenses and other current assets with no individual item accounting for more than 5% of the total balance at June 30, 2014 and December 31, 2013.
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Prepaid Expenses and Other Current Assets (Details) (USD $)
In Thousands, unless otherwise specified
Jun. 30, 2014
Dec. 31, 2013
Prepaid expenses and other current assets [Abstract]    
Kits for clinical use $ 327 $ 287
Insurance premiums 322 407
Professional fees 27 377
Income tax credits receivable 18 326
Other 158 [1] 314 [1]
Total prepaid expenses and other current assets $ 852 $ 1,711
Maximum percentage of prepaid expenses and other current assets (in hundredths) 5.00% 5.00%
[1] Other consists of various prepaid expenses and other current assets with no individual item accounting for more than 5% of the total balance at June 30, 2014 and December 31, 2013.
XML 21 R28.htm IDEA: XBRL DOCUMENT v2.4.0.8
Inventories (Details) (USD $)
In Thousands, unless otherwise specified
Jun. 30, 2014
Dec. 31, 2013
Inventories [Abstract]    
Raw materials $ 196 $ 249
Work-in-process 295 364
Finished goods 109 106
Total inventory $ 600 $ 719
XML 22 R30.htm IDEA: XBRL DOCUMENT v2.4.0.8
Property, Plant, and Equipment (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Dec. 31, 2013
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, gross $ 6,657   $ 6,657   $ 7,004
Accumulated depreciation (4,236)   (4,236)   (3,935)
Property, plant and equipment, net 2,421   2,421   3,069
Depreciation expense 300 300 499 604  
Enterprise Hardware and Software [Member]
         
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, gross 2,009   2,009   2,143
Leaseholds [Member]
         
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, gross 1,667   1,667   1,749
Equipment [Member]
         
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, gross 1,421   1,421   1,552
Furniture [Member]
         
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, gross 957   957   957
Buildings and Land [Member]
         
Property, Plant and Equipment [Line Items]          
Property, plant and equipment, gross $ 603   $ 603   $ 603
XML 23 R31.htm IDEA: XBRL DOCUMENT v2.4.0.8
Accrued Expenses (Details) (USD $)
In Thousands, unless otherwise specified
Jun. 30, 2014
Dec. 31, 2013
Accrued Expenses [Abstract]    
Compensation, excluding taxes $ 2,470 $ 1,866
Deferred rent 315 485
Professional fees 224 360
Short-term portion of lease restructuring 209 0
Other 869 [1] 1,029 [1]
Total accrued expenses $ 4,087 $ 3,740
Maximum percentage of current liabilities accrued (in hundredths) 5.00% 5.00%
Percentage of current annual salary as cash retention bonus (in hundredths) 50.00%  
[1] Other consists of various accrued expenses, with no individual item accounting for more than 5% of current liabilities at June 30, 2014 and December 31, 2013.
XML 24 R8.htm IDEA: XBRL DOCUMENT v2.4.0.8
Inventories
6 Months Ended
Jun. 30, 2014
Inventories [Abstract]  
Inventories
(2)Inventories

Inventories consist of the following:

(in thousands)
 
June 30,
2014
  
December 31,
2013
 
Raw materials
 
$
196
  
$
249
 
Work-in-process
  
295
   
364
 
Finished goods
  
109
   
106
 
Total inventory
 
$
600
  
$
719
 
XML 25 R32.htm IDEA: XBRL DOCUMENT v2.4.0.8
Restructuring Expenses (Details) (USD $)
6 Months Ended 3 Months Ended 12 Months Ended 18 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2014
Operating Lease [Member]
Jun. 30, 2014
Employee Costs [Member]
Jun. 30, 2014
Facility Closing [Member]
Jun. 30, 2014
Accrued Expenses [Member]
Jun. 30, 2014
Other non-current liabilities [Member]
Jun. 30, 2014
Operating Expense [Member]
Employee
Dec. 31, 2013
Operating Expense [Member]
Employee
Jun. 30, 2014
Operating Expense [Member]
Employee
Jun. 30, 2014
Selling, General and Administrative Expenses [Member]
Contract Termination [Member]
Restructuring Cost and Reserve [Line Items]                    
Number of positions eliminated             7 50 57  
Severance costs               $ 4,800,000    
Outstanding lease term       81 months            
Contractual Obligation       3,600,000            
Sub-lease revenue       2,600,000            
Contract termination costs related to sub-lease                   150,000
Leasehold improvements written off 50,000                  
Restructuring Reserve [Roll Forward]                    
Restructuring reserve balance   0 2,019,000   1,400,000 100,000        
Charges   855,000 722,000              
Restructuring expenses paid   0 (1,287,000)              
Restructuring reserve balance   $ 855,000 $ 1,454,000   $ 1,400,000 $ 100,000        
XML 26 R2.htm IDEA: XBRL DOCUMENT v2.4.0.8
Condensed Consolidated Balance Sheets (Unaudited) (USD $)
In Thousands, unless otherwise specified
Jun. 30, 2014
Dec. 31, 2013
Current assets    
Cash and cash equivalents $ 27,284 $ 31,249
Accounts receivables, net 172 349
Inventories, net 600 719
Prepaid expenses and other current assets 852 1,711
Total current assets 28,908 34,028
Property, plant and equipment, net 2,421 3,069
Total assets 31,329 37,097
Current liabilities    
Accounts payable 239 582
Accrued expenses 4,087 3,740
Warrant liability 1,075 2,310
Total current liabilities 5,401 6,632
Other non-current liabilities 748 366
Total liabilities 6,149 6,998
Commitments and contingencies (Note 11)      
Stockholders' equity    
Preferred stock, $.01 par value; 10,000,000 shares authorized; no shares issued and outstanding at June 30, 2014 and December 31, 2013 0 0
Common stock, $.01 par value; 170,000,000 shares authorized; 9,451,870 and 8,394,397 shares issued and 9,447,392 and 8,392,641 shares outstanding at June 30, 2014 and December 31, 2013, respectively * 95 [1] 84 [1]
Additional paid-in capital 264,072 259,102
Accumulated deficit (239,010) (229,132)
Treasury stock, at cost; 1,757 shares at June 30, 2014 and December 31, 2013 * (51) [1] (51) [1]
Accumulated other comprehensive income 74 96
Total stockholders' equity 25,180 30,099
Total liabilities and stockholders' equity $ 31,329 $ 37,097
[1] Reflects a one-for- sixteen (1:16) reverse stock split effected on April 8, 2014.
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Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $)
In Thousands, unless otherwise specified
6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Cash flows from operating activities:    
Net loss $ (9,878) $ (18,328)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock option compensation expense 257 571
Restricted stock compensation expense 60 241
Depreciation expense 499 604
Provision for inventory obsolescence 102 17
Warrant liability fair value adjustment (1,092) (2,842)
Loss on write-downs and disposals of equipment 123 5
Non-cash interest income 0 1
Changes in assets and liabilities:    
Decrease (increase) in prepaid expenses and other current assets 856 (132)
Decrease in accounts receivable 183 84
Decrease in inventories 15 157
Increase (decrease) in accounts payable and accrued expenses 7 (1,576)
Increase (decrease) in other non-current liabilities 383 (300)
Net cash used in operating activities (8,485) (21,498)
Cash flows from investing activities:    
Purchase of property, plant, and equipment 0 (79)
Proceeds from sales of property, plant, and equipment 22 0
Net cash provided by (used in) investing activities 22 (79)
Cash flows from financing activities:    
Net proceeds from sale of stock and exercise of stock options and warrants 4,521 29,975
Net cash provided by financing activities 4,521 29,975
Foreign currency effects on cash (23) 202
Net (decrease) increase in cash and cash equivalents (3,965) 8,600
Cash and cash equivalents:    
Beginning of period 31,249 23,726
End of period 27,284 32,326
Supplemental non-cash activities:    
Fair value of warrants exercised $ 143 $ 219
XML 29 R35.htm IDEA: XBRL DOCUMENT v2.4.0.8
Fair Value Measurements (Details) (USD $)
3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2014
Input
Derivative warrant liability [Abstract]    
Number of inputs used for valuation of warrants   6
Pre-tax derivative instrument expense $ 1,300,000 $ 1,100,000
Hypothetical change in market price of common shares (in hundredths)   10.00%
Impact of the hypothetical change in market price of common shares on derivative liability   200,000
Fair Value Measurements Using Significant Unobservable Inputs (Level 3) [Roll Forward]    
Beginning balance as of December 31, 2013   2,310,000
Total change in the fair value of the liability included in earnings, including warrant expairations   (1,092,000)
Fair value of warrants exercised   (143,000)
Ending balance as of June 30, 2014 1,075,000 1,075,000
Recurring [Member] | Warrant liability [Member]
   
Liabilities [Abstract]    
Total Liabilities 1,075,000 1,075,000
Recurring [Member] | Warrant liability [Member] | Level 1 [Member]
   
Liabilities [Abstract]    
Total Liabilities 0 0
Recurring [Member] | Warrant liability [Member] | Level 2 [Member]
   
Liabilities [Abstract]    
Total Liabilities 0 0
Recurring [Member] | Warrant liability [Member] | Level 3 [Member]
   
Liabilities [Abstract]    
Total Liabilities 1,075,000 1,075,000
Recurring [Member] | Money market funds [Member]
   
Assets [Abstract]    
Total Assets 1,945,000 1,945,000
Recurring [Member] | Money market funds [Member] | Level 1 [Member]
   
Assets [Abstract]    
Total Assets 1,945,000 1,945,000
Recurring [Member] | Money market funds [Member] | Level 2 [Member]
   
Assets [Abstract]    
Total Assets 0 0
Recurring [Member] | Money market funds [Member] | Level 3 [Member]
   
Assets [Abstract]    
Total Assets $ 0 $ 0
2012 Warrants [Member]
   
Derivative warrant liability [Abstract]    
Expected volatility (in hundredths)   111.35%
Risk-free interest rates (in hundredths)   0.11%
Expected life (in years)   0 years 11 months 1 day
2013 Warrants [Member]
   
Derivative warrant liability [Abstract]    
Expected volatility (in hundredths)   94.18%
Risk-free interest rates (in hundredths)   1.34%
Expected life (in years)   4 years 3 months 29 days
XML 30 R22.htm IDEA: XBRL DOCUMENT v2.4.0.8
Property, Plant, and Equipment (Tables)
6 Months Ended
Jun. 30, 2014
Property, Plant, and Equipment [Abstract]  
Components of property, plant and equipment
Property, plant, and equipment consist of the following:

(in thousands)
 
June 30,
2014
  
December 31,
2013
 
Enterprise hardware and software
 
$
2,009
  
$
2,143
 
Leaseholds
  
1,667
   
1,749
 
Equipment
  
1,421
   
1,552
 
Furniture
  
957
   
957
 
Buildings and land
  
603
   
603
 
Property, plant and equipment, gross
  
6,657
   
7,004
 
Accumulated depreciation
  
(4,236
)
  
(3,935
)
Property, plant and equipment, net
 
$
2,421
  
$
3,069
 
XML 31 R36.htm IDEA: XBRL DOCUMENT v2.4.0.8
Net Loss per Common Share (Details) (USD $)
In Thousands, except Share data, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Calculation of net loss and the number of shares used to compute basic and diluted earnings per share [Abstract]        
Net loss - basic $ (4,600) $ (5,482) $ (9,878) $ (18,328)
Adjustment for gain on warrant derivative liability (356) 0 (363) 0
Net loss - diluted $ (4,956) $ (5,482) $ (10,241) $ (18,328)
Weighted average shares outstanding - basic (in shares) 9,426,169 [1] 6,023,785 [1] 9,363,123 [1] 5,683,380 [1]
Adjustment for warrant exercises (in shares) 54,764 0 99,594 0
Weighted average shares outstanding - diluted (in shares) 9,480,933 [1] 6,023,785 [1] 9,462,717 [1] 5,683,380 [1]
Net loss per share - basic (in dollars per share) $ (0.49) [1] $ (0.91) [1] $ (1.06) [1] $ (3.22) [1]
Net loss per share - diluted (in dollars per share) $ (0.52) [1] $ (0.91) [1] $ (1.08) [1] $ (3.22) [1]
Antidilutive securities excluded from computation of earnings per share (in shares)     791,451 688,208
Stock Options [Member]
       
Calculation of net loss and the number of shares used to compute basic and diluted earnings per share [Abstract]        
Antidilutive securities excluded from computation of earnings per share (in shares)     199,230 323,417
Unvested Restricted Stock [Member]
       
Calculation of net loss and the number of shares used to compute basic and diluted earnings per share [Abstract]        
Antidilutive securities excluded from computation of earnings per share (in shares)     2,721 24,797
Warrants [Member]
       
Calculation of net loss and the number of shares used to compute basic and diluted earnings per share [Abstract]        
Antidilutive securities excluded from computation of earnings per share (in shares)     589,500 339,994
[1] Reflects a one-for- sixteen (1:16) reverse stock split effected on April 8, 2014.
XML 32 R24.htm IDEA: XBRL DOCUMENT v2.4.0.8
Restructuring Expenses (Tables)
6 Months Ended
Jun. 30, 2014
Restructuring Expenses [Abstract]  
Schedule of restructuring and related costs
The following table provides the year-to-date activity of the Company’s restructuring reserves as of June 30, 2014:

(in thousands)
 
Employee
 Costs
  
Operating
 Lease
 
Reserve balance as of December 31, 2013
 
$
2,019
  
$
 
Charges
  
722
   
855
 
Payments / utilizations
  
(1,287
)
  
 
Reserve balance as of June 30, 2014
 
$
1,454
  
$
855
 
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General
6 Months Ended
Jun. 30, 2014
General [Abstract]  
General
(1)General

The interim Condensed Consolidated Financial Statements of Delcath Systems, Inc. (“Delcath” or the “Company”) for the three and six months ended June 30, 2014 and 2013 should be read in conjunction with the Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K (“Annual Report”) for the year ended December 31, 2013, which has been filed with the Securities Exchange Commission (“SEC”) and can also be found on the Company’s website (www.delcath.com). In these notes the terms “us”, “we” or “our” refer to Delcath and its consolidated subsidiaries.

On April 8, 2014, the Company effected a one-for-sixteen (1:16) reverse stock split. Refer to Note 7 Stockholders’ Equity of these Condensed Consolidated Financial Statements for further information.

Description of Business

Delcath Systems, Inc. is a specialty pharmaceutical and medical device company focused on oncology. Our proprietary product—Melphalan Hydrochloride for Injection for use with the Delcath Hepatic Delivery System (Melphalan HDS)—is designed to administer high dose chemotherapy to the liver, while controlling the systemic exposure to those agents. The Company's principal focus is on the treatment of primary and metastatic liver cancers.

In the United States, Melphalan HDS is considered a combination drug and device product, and is regulated as a drug by the United States Food and Drug Administration (FDA). Melphalan HDS has not been approved for sale in the United States. In Europe, our proprietary system to deliver and filter melphalan hydrochloride is marketed as a device under the trade name Delcath Hepatic CHEMOSAT® Delivery System for Melphalan (CHEMOSAT). In April 2012, we obtained authorization to affix a CE Mark for Generation Two CHEMOSAT.  The right to affix the CE mark allows the Company to market and sell CHEMOSAT in Europe. The Company has initiated plans to investigate Melphalan HDS for primary liver cancer.

The Company has incurred losses since inception. The Company anticipates incurring additional losses until such time, if ever, that it can generate significant sales. Management believes that its capital resources are adequate to fund operations through the first half of 2015, but anticipates that additional working capital may be required to continue operations. To the extent additional capital is not available when needed, the Company may be forced to abandon some or all of its development and commercialization efforts, which would have a material adverse effect on the prospects of the business.  Operations of the Company are subject to certain risks and uncertainties, including, among others, uncertainties and risks related to product development; regulatory approvals; technology; patents and proprietary rights; comprehensive government regulations; limited commercial manufacturing; marketing and sales experience; and dependence on key personnel.

Basis of Presentation

These interim Condensed Consolidated Financial Statements are unaudited and were prepared by the Company in accordance with generally accepted accounting principles in the United States of America (GAAP) and with the SEC’s instructions to Form 10-Q and Article 10 of Regulation S-X. They include the accounts of all entities controlled by Delcath and all significant inter-company accounts and transactions have been eliminated in consolidation.
 
The preparation of interim financial statements requires management to make assumptions and estimates that impact the amounts reported. These interim Condensed Consolidated Financial Statements, in the opinion of management, reflect all adjustments, consisting of normal recurring accruals, necessary for a fair presentation of the Company’s results of operations, financial position and cash flows for the interim periods ended June 30, 2014 and 2013; however, certain information and footnote disclosures normally included in our Annual Report have been condensed or omitted as permitted by GAAP. It is important to note that the Company’s results of operations and cash flows for interim periods are not necessarily indicative of the results of operations and cash flows to be expected for a full fiscal year.

Significant Accounting Policies

A description of our significant accounting policies has been provided in Note 3 Summary of Significant Accounting Policies to the Consolidated Financial Statements included in our Annual Report.
 
Recently Adopted Accounting Pronouncements

In March 2013, the FASB issued ASU 2013-05, Foreign Currency Matters (Topic 830): Parent's Accounting for the Cumulative Translation Adjustment upon Derecognition of Certain Subsidiaries or Groups of Assets within a Foreign Entity or of an Investment in a Foreign Entity, which permits an entity to release cumulative translation adjustments into net income when a reporting entity (parent) ceases to have a controlling financial interest in a subsidiary or group of assets that is a business within a foreign entity.  Accordingly, the cumulative translation adjustment should be released into net income only if the sale or transfer results in the complete or substantially complete liquidation of the foreign entity in which the subsidiary or group of assets had resided, or, if a controlling financial interest is no longer held. The revised standard became effective for fiscal years beginning after December 15, 2013. The Company adopted this guidance effective January 1, 2014.  The Company’s adoption of this standard did not have a material impact on its consolidated financial statements.

Accounting Pronouncements Not Yet Adopted

In May 2014, the FASB issued ASU 2014-09, Revenue from Contracts with Customers (“ASU 2014-09”) that updates the principles for recognizing revenue. The core principle of the guidance is that an entity should recognize revenue to depict the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. ASU 2014-09 also amends the required disclosures of the nature, amount, timing and uncertainty of revenue and cash flows arising from contracts with customers. ASU 2014-09 is effective for annual reporting periods beginning after December 15, 2016, including interim periods within that reporting period. The Company expects to adopt this guidance when effective, and the impact on our financial statements is not currently estimable.

In June 2014, the FASB issued ASU 2014-12, Accounting for Share-Based Payments When the Terms of an Award Provide That a Performance Target Could Be Achieved after the Requisite Service Period (“ASU 2014-12”). ASU 2014-12 requires that a performance target that affects vesting and that could be achieved after the requisite service period be treated as a performance condition. As such, the performance target should not be reflected in estimating the grant-date fair value of the award. ASU 2014-12 is effective for annual reporting periods beginning after December 15, 2015, with early adoption permitted. The Company is evaluating the potential impacts of the new standard on its existing stock-based compensation plans.
XML 35 R3.htm IDEA: XBRL DOCUMENT v2.4.0.8
Condensed Consolidated Balance Sheets (Unaudited) (Parenthetical) (USD $)
3 Months Ended 12 Months Ended
Jun. 30, 2014
Dec. 31, 2013
Stockholders' equity    
Preferred stock, par value (in dollars per share) $ 0.01 $ 0.01
Preferred stock, shares authorized (in shares) 10,000,000 10,000,000
Preferred stock, shares issued (in shares) 0 0
Preferred stock, shares outstanding (in shares) 0 0
Common stock, par value (in dollars per share) $ 0.01 $ 0.01
Common stock, shares authorized (in shares) 170,000,000 170,000,000
Common stock, shares issued (in shares) 9,451,870 8,394,397
Common stock, shares outstanding (in shares) 9,447,392 8,392,641
Treasury stock, at cost (in shares) 1,757 1,757
Reverse stock split ratio one-for- sixteen (1:16) one-for- sixteen (1:16)
XML 36 R17.htm IDEA: XBRL DOCUMENT v2.4.0.8
Commitments and Contingencies
6 Months Ended
Jun. 30, 2014
Commitments and Contingencies [Abstract]  
Commitments and Contingencies
(11)Commitment and Contingencies

The Company is a party to several legal proceedings. Refer to Part II, Item 1 Legal Proceedings in this Quarterly Report on Form 10-Q for more information.
XML 37 R1.htm IDEA: XBRL DOCUMENT v2.4.0.8
Document and Entity Information
6 Months Ended
Jun. 30, 2014
Aug. 04, 2014
Document and Entity Information [Abstract]    
Entity Registrant Name DELCATH SYSTEMS, INC.  
Entity Central Index Key 0000872912  
Current Fiscal Year End Date --12-31  
Entity Well-known Seasoned Issuer No  
Entity Voluntary Filers No  
Entity Current Reporting Status Yes  
Entity Filer Category Non-accelerated Filer  
Entity Common Stock, Shares Outstanding   9,451,930
Document Fiscal Year Focus 2014  
Document Fiscal Period Focus Q2  
Document Type 10-Q  
Amendment Flag false  
Document Period End Date Jun. 30, 2014  
XML 38 R18.htm IDEA: XBRL DOCUMENT v2.4.0.8
Subsequent Events
6 Months Ended
Jun. 30, 2014
Subsequent Events [Abstract]  
Subsequent Events
(12)
Subsequent Events

The Company completed an evaluation of the impact of any subsequent events through the date financial statements were issued and determined there were no other subsequent events requiring disclosure in or adjustment to these financial statements.
XML 39 R4.htm IDEA: XBRL DOCUMENT v2.4.0.8
Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) (USD $)
In Thousands, except Share data, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
REVENUES        
Product revenues $ 251 $ 0 $ 561 $ 81
Other revenues 0 0 0 300
Total revenues 251 0 561 381
COSTS OF SALES        
Costs of goods sold (66) (332) (160) (363)
Gross profit 185 (332) 401 18
OPERATING EXPENSES        
Selling, general and administrative 4,597 6,263 8,416 12,346
Research and development 1,492 3,992 2,949 8,462
Total operating expenses 6,089 10,255 11,365 20,808
Loss from operations (5,904) (10,587) (10,964) (20,790)
OTHER INCOME (EXPENSE)        
Change in fair value of warrant liability, net 1,297 5,115 1,092 2,842
Interest income 1 5 2 15
Other expenses 6 (15) (8) (395)
Net loss (4,600) (5,482) (9,878) (18,328)
LOSS PER COMMON SHARE        
Basic loss per common share (in dollars per share) $ (0.49) [1] $ (0.91) [1] $ (1.06) [1] $ (3.22) [1]
Diluted loss per common share (in dollars per share) $ (0.52) [1] $ (0.91) [1] $ (1.08) [1] $ (3.22) [1]
WEIGHTED AVERAGE COMMON SHARES        
Basic weighted average common shares outstanding (in shares) 9,426,169 [1] 6,023,785 [1] 9,363,123 [1] 5,683,380 [1]
Diluted weighted average common shares outstanding (in shares) 9,480,933 [1] 6,023,785 [1] 9,462,717 [1] 5,683,380 [1]
OTHER COMPREHENSIVE INCOME (LOSS)        
Foreign currency translation adjustments (20) 6 (22) 369
Comprehensive loss $ (4,620) $ (5,476) $ (9,900) $ (17,959)
[1] Reflects a one-for- sixteen (1:16) reverse stock split effected on April 8, 2014.
XML 40 R12.htm IDEA: XBRL DOCUMENT v2.4.0.8
Restructuring Expenses
6 Months Ended
Jun. 30, 2014
Restructuring Expenses [Abstract]  
Restructuring Expenses
(6)Restructuring Expenses

During 2013, the Company implemented workforce restructurings to better focus its organizational structure, increase efficiency and concentrate financial resources on its clinical development program and European commercialization activity. This resulted in a total reduction in the Company’s workforce by 50 employees. During the second quarter of 2014, the Company implemented additional workforce restructurings that resulted in a total reduction in the Company’s workforce by seven employees. As a result of termination benefits provided to these 57 employees the Company has incurred a total restructuring charge of approximately $4.8 million for employee related expenses. At June 30, 2014, the remaining restructuring reserve of approximately $1.5 million is included in Accrued expenses and Other non-current liabilities on the Condensed Consolidated Balance Sheets for approximately $1.4 million and $0.1 million, respectively.
 
In order to more appropriately align its office space with the reduced size of its workforce, during the quarter ended June 30, 2014, the Company implemented a plan to vacate and sub-lease office space at its 810 Seventh Avenue location in New York, NY. On May 22, 2014, the Company entered into a sub-lease agreement for approximately one-half of the office space at this location and had vacated and relinquished the premises to the sub-tenant as of June 30, 2014. At June 30, 2014, future rent obligations for the vacated space under the Company’s Prime Lease over the remaining lease term of 81 months totaled approximately $3.6 million. Under its new sub-lease agreement for the vacated space the Company will receive future sub-lease rental receipts totaling approximately $2.6 million, resulting in net future cash outflows of approximately $1.0 million. In accordance with ASC 420, Exit or Disposal Cost Obligations, the Company calculated the fair value of the remaining net cash flow liability for the vacated space and recorded a lease restructuring reserve of approximately $0.9 million. Additionally, during the quarter ended June 30, 2014, the Company recorded contract termination costs related to the sub-lease of approximately $150,000 and wrote off approximately $50,000 of unamortized leasehold improvements related to the vacated space. The expenses related to this lease restructuring have been recorded in Selling, general and administrative on the Condensed Consolidated Statements of Operations while the fair value of the liability has been included in both Accrued expenses and Other non-current liabilities on the Condensed Consolidated Balance Sheets.

The following table provides the year-to-date activity of the Company’s restructuring reserves as of June 30, 2014:

(in thousands)
 
Employee
 Costs
  
Operating
 Lease
 
Reserve balance as of December 31, 2013
 
$
2,019
  
$
 
Charges
  
722
   
855
 
Payments / utilizations
  
(1,287
)
  
 
Reserve balance as of June 30, 2014
 
$
1,454
  
$
855
 
XML 41 R11.htm IDEA: XBRL DOCUMENT v2.4.0.8
Accrued Expenses
6 Months Ended
Jun. 30, 2014
Accrued Expenses [Abstract]  
Accrued Expenses
(5)Accrued Expenses

Accrued expenses consist of the following:
 
(in thousands)
 
June 30,
2014
  
December 31,
2013
 
Compensation, excluding taxes
 
$
2,470
  
$
1,866
 
Deferred rent
  
315
   
485
 
Professional fees
  
224
   
360
 
Short-term portion of lease restructuring
  
209
   
 
Other1
  
869
   
1,029
 
Total accrued expenses
 
$
4,087
  
$
3,740
 
 
1 Other consists of various accrued expenses, with no individual item accounting for more than 5% of current liabilities at June 30, 2014 and December 31, 2013.
 
In November 2013, the Board of Directors approved an Employee Retention Program for certain key employees, including the Company’s executive officers. The key employees will be eligible to receive a cash retention bonus payment equal to fifty percent (50%) of their current annual salary if they remain employed by the Company through March 31, 2015. The expense related to this program is being accrued ratably over the required service period and has been included in Accrued expenses on the Condensed Consolidated Balance Sheets and in both Selling, general and administrative and Research and development on the Condensed Consolidated Statements of Operations.

For a description of the Company’s lease restructuring liability refer to Note 6 Restructuring Expenses of these Condensed Consolidated Financial Statements.
XML 42 R23.htm IDEA: XBRL DOCUMENT v2.4.0.8
Accrued Expenses (Tables)
6 Months Ended
Jun. 30, 2014
Accrued Expenses [Abstract]  
Schedule of accrued expenses
Accrued expenses consist of the following:
 
(in thousands)
 
June 30,
2014
  
December 31,
2013
 
Compensation, excluding taxes
 
$
2,470
  
$
1,866
 
Deferred rent
  
315
   
485
 
Professional fees
  
224
   
360
 
Short-term portion of lease restructuring
  
209
   
 
Other1
  
869
   
1,029
 
Total accrued expenses
 
$
4,087
  
$
3,740
 
 
1 Other consists of various accrued expenses, with no individual item accounting for more than 5% of current liabilities at June 30, 2014 and December 31, 2013.
XML 43 R19.htm IDEA: XBRL DOCUMENT v2.4.0.8
General (Policies)
6 Months Ended
Jun. 30, 2014
General [Abstract]  
Basis of Presentation
Basis of Presentation

These interim Condensed Consolidated Financial Statements are unaudited and were prepared by the Company in accordance with generally accepted accounting principles in the United States of America (GAAP) and with the SEC’s instructions to Form 10-Q and Article 10 of Regulation S-X. They include the accounts of all entities controlled by Delcath and all significant inter-company accounts and transactions have been eliminated in consolidation.
 
The preparation of interim financial statements requires management to make assumptions and estimates that impact the amounts reported. These interim Condensed Consolidated Financial Statements, in the opinion of management, reflect all adjustments, consisting of normal recurring accruals, necessary for a fair presentation of the Company’s results of operations, financial position and cash flows for the interim periods ended June 30, 2014 and 2013; however, certain information and footnote disclosures normally included in our Annual Report have been condensed or omitted as permitted by GAAP. It is important to note that the Company’s results of operations and cash flows for interim periods are not necessarily indicative of the results of operations and cash flows to be expected for a full fiscal year.
Recently Adopted Accounting Pronouncements
Recently Adopted Accounting Pronouncements

In March 2013, the FASB issued ASU 2013-05, Foreign Currency Matters (Topic 830): Parent's Accounting for the Cumulative Translation Adjustment upon Derecognition of Certain Subsidiaries or Groups of Assets within a Foreign Entity or of an Investment in a Foreign Entity, which permits an entity to release cumulative translation adjustments into net income when a reporting entity (parent) ceases to have a controlling financial interest in a subsidiary or group of assets that is a business within a foreign entity.  Accordingly, the cumulative translation adjustment should be released into net income only if the sale or transfer results in the complete or substantially complete liquidation of the foreign entity in which the subsidiary or group of assets had resided, or, if a controlling financial interest is no longer held. The revised standard became effective for fiscal years beginning after December 15, 2013. The Company adopted this guidance effective January 1, 2014.  The Company’s adoption of this standard did not have a material impact on its consolidated financial statements.
Accounting Pronouncements Not Yet Adopted
Accounting Pronouncements Not Yet Adopted

In May 2014, the FASB issued ASU 2014-09, Revenue from Contracts with Customers (“ASU 2014-09”) that updates the principles for recognizing revenue. The core principle of the guidance is that an entity should recognize revenue to depict the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. ASU 2014-09 also amends the required disclosures of the nature, amount, timing and uncertainty of revenue and cash flows arising from contracts with customers. ASU 2014-09 is effective for annual reporting periods beginning after December 15, 2016, including interim periods within that reporting period. The Company expects to adopt this guidance when effective, and the impact on our financial statements is not currently estimable.

In June 2014, the FASB issued ASU 2014-12, Accounting for Share-Based Payments When the Terms of an Award Provide That a Performance Target Could Be Achieved after the Requisite Service Period (“ASU 2014-12”). ASU 2014-12 requires that a performance target that affects vesting and that could be achieved after the requisite service period be treated as a performance condition. As such, the performance target should not be reflected in estimating the grant-date fair value of the award. ASU 2014-12 is effective for annual reporting periods beginning after December 15, 2015, with early adoption permitted. The Company is evaluating the potential impacts of the new standard on its existing stock-based compensation plans.
XML 44 R15.htm IDEA: XBRL DOCUMENT v2.4.0.8
Net Loss per Common Share
6 Months Ended
Jun. 30, 2014
Net Loss per Common Share [Abstract]  
Net Loss per Common Share
(9)
Net Loss per Common Share

Basic net loss per share is determined by dividing net loss by the weighted average shares of common stock outstanding during the period. Diluted net loss per share is determined by dividing net loss by diluted weighted average shares outstanding. Diluted weighted average shares reflects the dilutive effect, if any, of potentially dilutive common shares, such as stock options and warrants calculated using the treasury stock method. In periods with reported net operating losses, all common stock options and warrants are deemed anti-dilutive such that basic net loss per share and diluted net loss per share are equal. However, in certain periods in which the exercise price of the warrants was less than the last reported sales price of Delcath’s common stock on the final trading day of the period and there is a gain recorded pursuant to the change in fair value of the warrant derivative liability, the impact of gains related to the mark-to-market adjustment of the warrants outstanding at the end of the period is reversed and the treasury stock method is used to determine diluted earnings per share.

The calculation of net loss and the number of shares used to compute basic and diluted earnings per share for the three and six month periods ended June 30, 2014 and 2013 are as follows:

 
 
Three months ended
June 30,
  
Six months ended
June 30,
 
(in thousands, except share data)
 
2014
  
2013
  
2014
  
2013
 
Net loss – basic
 
$
(4,600
)
 
$
(5,482
)
 
$
(9,878
)
 
$
(18,328
)
Adjustment for gain on warrant derivative liability
  
(356
)
  
   
(363
)
  
 
Net loss – diluted
 
$
(4,956
)
 
$
(5,482
)
 
$
(10,241
)
 
$
(18,328
)
 
                
Weighted average shares outstanding – basic
  
9,426,169
   
6,023,785
   
9,363,123
   
5,683,380
 
Adjustment for warrant exercises
  
54,764
   
   
99,594
   
 
Weighted average shares outstanding – diluted
  
9,480,933
   
6,023,785
   
9,462,717
   
5,683,380
 
 
                
Net loss per share – basic
 
$
(0.49
)
 
$
(0.91
)
 
$
(1.06
)
 
$
(3.22
)
Net loss per share – diluted
 
$
(0.52
)
 
$
(0.91
)
 
$
(1.08
)
 
$
(3.22
)
 
The following potentially dilutive securities were excluded from the computation of earnings per share as of June 30, 2014 and 2013 because their effects would be anti-dilutive:

 
 
June 30,
 
 
 
2014
  
2013
 
Stock options
  
199,230
   
323,417
 
Unvested restricted shares
  
2,721
   
24,797
 
Warrants
  
589,500
   
339,994
 
Total
  
791,451
   
688,208
 
XML 45 R13.htm IDEA: XBRL DOCUMENT v2.4.0.8
Stockholders Equity
6 Months Ended
Jun. 30, 2014
Stockholders Equity [Abstract]  
Stockholders Equity
(7)Stockholders’ Equity

Stock Issuances

Reverse Stock Split

On February 24, 2014, shareholders of the Company approved, through a shareholder vote, an amendment to the Company’s Amended and Restated Certificate of Incorporation authorizing the Board of Directors to effect a reverse stock split of Delcath’s common stock. The reverse stock split became effective on April 8, 2014 at which time Delcath’s common stock began trading on the NASDAQ Stock Exchange on a one-for-sixteen (1:16) split-adjusted basis. All owners of record as of the close of the NASDAQ market on April 8, 2014 received one issued and outstanding share of Delcath common stock in exchange for sixteen issued and outstanding shares of Delcath common stock. No fractional shares were issued in connection with the reverse stock split. All fractional shares created by the one-for-sixteen exchange were rounded up to the next whole share. The reverse stock split had no impact on the number of common shares authorized or the par value per share of Delcath common stock, which remain 170,000,000 and $0.01, respectively. All current and prior period amounts related to shares, share prices and earnings per share, presented in these Condensed Consolidated Financial Statements and the accompanying Notes, have been restated to give retrospective presentation for the reverse stock split.

At-the-Market (“ATM”) Programs

In December 2011, the Company entered into an agreement with Cowen and Company, LLC (“Cowen”) to sell shares of its common stock, par value $.01 per share, from time to time, through an ATM equity offering program having aggregate sales proceeds of $39.8 million, under which Cowen would act as sales agent. During the first quarter of 2013, the Company sold approximately 14.2 million shares of its common stock under this ATM program for proceeds of approximately $20.9 million, with net cash proceeds after related expenses of approximately $20.8 million, and successfully completed the program. As of March 31, 2013, there were no shares of common stock of the Company remaining for sale under this ATM program.
 
In March 2013, the Company entered into a new agreement with Cowen to sell shares of the Company’s common stock, par value $.01 per share, from time to time, through an ATM equity offering program having aggregate sales proceeds of $50.0 million, under which Cowen will act as sales agent. During the year ended December 31, 2013, the Company sold approximately 1.0 million shares of its common stock under this ATM program for proceeds of approximately $5.0 million, with net cash proceeds after related expenses of approximately $4.8 million. During the first quarter of 2014 the Company sold an additional 1.0 million shares of its common stock under this ATM program for proceeds of approximately $4.4 million, with net cash proceeds after related expenses of approximately $4.4 million. The shares were issued pursuant to an effective registration statement on Form S-3 (333-187230). The net proceeds will be used for general corporate purposes, including, but not limited to, commercialization of our products, obtaining regulatory approvals, funding of our clinical trials, capital expenditures and working capital. There were no shares of common stock sold under the ATM program during the second quarter of 2014. As of June 30, 2014, the Company has approximately $40.4 million remaining under the program.

Committed Equity Financing Facility (“CEFF”) Program

In December 2012, the Company entered into an agreement with Terrapin Opportunity, L.P. (“Terrapin”) for a CEFF program. Under the agreement Terrapin committed to purchase up to $35.0 million of Delcath common stock over a 24-month term. Since inception, the Company has sold approximately 0.5 million shares of its common stock through the program for total proceeds of approximately $11.1 million, with net cash proceeds after related expenses of approximately $10.8 million. As a result, there was approximately $23.9 million available under this CEFF program as of June 30, 2014. The shares were issued pursuant to an effective registration statement on Form S-3 (333-183675). The net proceeds will be used for general corporate purposes including, but not limited to, commercialization of our products, obtaining regulatory approvals, funding of our clinical trials, capital expenditures and general working capital needs.

Warrants

In June 2009, the Company completed the sale of 0.1 million shares of its common stock and the issuance of warrants to purchase 0.1 million common shares (the “2009 Warrants”) pursuant to a subscription agreement with a single investor. The Company received proceeds of $3.0 million, with net cash proceeds after related expenses from this transaction of approximately $2.7 million. Of those proceeds, the Company allocated an estimated fair value of $2.2 million to the 2009 Warrants. As required by the 2009 Warrant agreement, the exercise price of the warrants was adjusted following the Company’s October 2013 sale of common stock and warrants. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. During the six months ended June 30, 2014, 35,000 2009 Warrants were exercised for net proceeds of approximately $0.1 million. The 2009 Warrants had a five-year term which expired on June 15, 2014. The remaining liability after warrant exercises was credited to pre-tax derivative instrument income.

In May 2012, the Company completed the sale of 1.0 million shares of its common stock and the issuance of warrants to purchase 0.3 million common shares (the “2012 Warrants”) pursuant to an underwriting agreement. The Company received proceeds of $21.5 million, with net cash proceeds after related expenses from this transaction of approximately $21.1 million. Of those proceeds, the Company allocated an estimated fair value of $3.4 million to the 2012 Warrants. As required by the 2012 Warrant agreement, the exercise price of the warrants was adjusted following the Company’s October 2013 sale of common stock and warrants. At June 30, 2014, the 2012 Warrants were exercisable at $2.56 per share with approximately 260,000 warrants outstanding. The 2012 Warrants have a three-year term. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. During the six months ended June 30, 2014, approximately 13,000 2012 Warrants were exercised for net proceeds of approximately $34,000.

In October 2013, the Company completed the sale of 1.3 million shares of its common stock and the issuance of warrants to purchase 0.6 million common shares (the “2013 Warrants”) pursuant to a placement agency agreement. The Company received proceeds of $7.5 million, with net cash proceeds after related expenses from this transaction of approximately $6.9 million. Of those proceeds, the Company allocated an estimated fair value of $1.9 million to the 2013 Warrants. The 2013 Warrants became exercisable on April 30, 2014 and at June 30, 2014, the 2013 Warrants were exercisable at $7.04 per share with 0.6 million warrants outstanding. The 2013 Warrants have a five-year term. The shares and warrants were issued pursuant to an effective registration statement on Form S-3. There were no 2013 Warrants exercised during the six months ended June 30, 2014.
 
Stock Incentive Plans

The Company established the 2004 Stock Incentive Plan and the 2009 Stock Incentive Plan (collectively, the “Plans”) under which 187,500, and 406,250 shares, respectively, have been reserved for the issuance of stock options, stock appreciation rights, restricted stock, stock grants and other equity awards. The Plans are administered by the Compensation and Stock Option Committee of the Board of Directors which determines the individuals to whom awards shall be granted as well as the type, terms, conditions, option price and the duration of each award.

A stock option grant allows the holder of the option to purchase a share of the Company’s common stock in the future at a stated price. Options granted under the Plans vest as determined by the Company’s Compensation and Stock Option Committee and expire over varying terms, but not more than ten years from the date of grant. Stock option activity for the six months ended June 30, 2014 is as follows:
 
 
 
Stock Option Activity under the Plans
 
 
 
Stock
Options
  
Exercise
Price
per Share
  
Weighted
Average
Exercise
Price
  
Weighted
Average
Remaining
Life
(Years)
 
Outstanding at December 31, 2013
  
252,158
  
$
4.80 — $248.64
  
$
57.90
   
7.36
 
Granted
  
   
   
     
Forfeited
  
(52,303
)
 
$
5.92 — $248.64
   
75.99
     
Expired
  
(625
)
 
$
58.56 — $58.56
   
58.56
     
Outstanding at June 30, 2014
  
199,230
  
$
4.80 — $248.64
  
$
53.16
   
7.08
 
 
For the three and six months ended June 30, 2014, the Company recognized compensation expense of approximately $0.1 million and $0.3 million, respectively, relating to stock options granted to employees.  For the three and six months ended June 30, 2013, the Company recognized compensation expense of approximately $0.1 million and $0.6 million, respectively, relating to stock options granted to employees.

There were no options granted during the six months ended June 30, 2014. The estimated fair value of each option award granted during the six month period ended June 30, 2013 was determined on the date of grant using an option pricing model with the following assumptions:
 
 
 
Six months ended
June 30, 2013
 
Dividend yield
 
None
 
Expected volatility
  
86.16% — 93.68%
Weighted average volatility
  
86.21%
 
Risk-free interest rates
  
0.99% — 1.36%
 
Expected life (in years)
  
6.8
 
 
No dividend yield was assumed because the Company has never paid a cash dividend on its common stock and does not expect to pay dividends in the foreseeable future. Volatilities were developed using the Company’s historical volatility. The risk-free interest rate was developed using the U.S. Treasury yield for periods equal to the expected life of the stock options on the grant date. The expected option term for grants made during the second half of 2012 and thereafter is based on actual historical results. The expected option term for grants made prior to that was developed based on the mid-point between the vesting date and the expiration date of each respective grant as permitted under ASC 718. This method of determining the expected holding period was utilized at that time because the Company did not yet have sufficient historical experience from which to estimate the period.
 
Restricted stock activity for the six months ended June 30, 2014 is as follows:
 
 
 
Restricted Stock Activity
under the Plans
 
 
 
Restricted
Stock
  
Weighted Average
Grant Date
Fair Value
 
Non-vested at December 31, 2013
  
20,347
  
$
16.84
 
Granted
  
   
 
Vested
  
(17,233
)
  
12.70
 
Forfeited
  
(393
)
  
38.24
 
Non-vested at June 30, 2014
  
2,721
  
$
39.98
 

For the three and six months ended June 30, 2014, the Company recognized compensation expense of approximately $0.02 million and $0.06 million, respectively, related to restricted stock granted to employees.  For the three and six months ended June 30, 2013, the Company recognized compensation expense of approximately $0.1 million and $0.2 million, respectively, related to restricted stock granted to employees.
XML 46 R14.htm IDEA: XBRL DOCUMENT v2.4.0.8
Fair Value Measurements
6 Months Ended
Jun. 30, 2014
Fair Value Measurements [Abstract]  
Fair Value Measurements
(8)Fair Value Measurements

Derivative Warrant Liability

As disclosed in Note 7 Stockholders’ Equity of these Condensed Consolidated Financial Statements, the Company allocated part of the proceeds of public offerings in 2009, 2012 and 2013 of the Company’s common stock to warrants issued in connection with those transactions. The valuation of the warrants was determined using an option pricing model. This model uses inputs such as the underlying price of the shares issued when the warrant is exercised, volatility, risk free interest rate and expected life of the instrument. The Company has determined that the warrants should be classified as liabilities and has accounted for them as derivative instruments in accordance with ASC 815. Additionally, the Company has determined that the warrant derivative liability should be classified within Level 3 of the fair-value hierarchy by evaluating each input for the option pricing model against the fair-value hierarchy criteria and using the lowest level of input as the basis for the fair-value classification as called for in ASC 820. There are six inputs: closing price of Delcath stock on the day of evaluation; the exercise price of the warrants; the remaining term of the warrants; the volatility of Delcath’s stock over that term; annual rate of dividends; and the riskless rate of return. Of those inputs, the exercise price of the warrants and the remaining term are readily observable in the warrant agreements. The annual rate of dividends is based on the Company’s historical practice of not granting dividends. The closing price of Delcath stock would fall under Level 1 of the fair-value hierarchy as it is a quoted price in an active market (ASC 820-10). The riskless rate of return is a Level 2 input as defined in ASC 820-10, while the historical volatility is a Level 3 input as defined in ASC 820. Since the lowest level input is a Level 3, Delcath determined the warrant derivative liability is most appropriately classified within Level 3 of the fair value hierarchy.

For the three and six months ended June 30, 2014, the Company recorded pre-tax derivative warrant income of $1.3 million and $1.1 million, respectively. The resulting derivative warrant liabilities totaled $1.1 million at June 30, 2014. In the event of a hypothetical 10% increase in the market price of our common shares on which the June 30, 2014 valuation was based, the value of the derivative liability would have increased by $0.2 million. Management expects that the warrants will either be exercised or expire worthless. The fair value of the warrants at June 30, 2014 was determined by using an option pricing model with the following assumptions:

 
 
2013
Warrants
  
2012
Warrants
 
Expected volatility
  
94.18%
  
111.35%
 
Risk-free interest rates
  
1.34%
 
  
0.11%
 
Expected life (in years)
  
4.33
   
0.92
 
 
Money Market Funds

The Company has determined that the inputs associated with the fair value determination of its money market funds are based on quoted prices (unadjusted) and, as a result, the investments have been classified within Level 1 of the fair value hierarchy.
 
The table below presents the Company’s assets and liabilities measured at fair value on a recurring basis as of June 30, 2014, aggregated by the level in the fair value hierarchy within which those measurements fall.

 
Assets and Liabilities Measured at Fair Value
on a Recurring Basis
 
(in thousands)
Level 1
 
Level 2
 
Level 3
 
Balance at
June 30, 2014
 
Assets
 
 
 
 
Money market funds
 
$
1,945
  
$
  
$
  
$
1,945
 
Liabilities
                
Warrant liability
 
$
  
$
  
$
1,075
  
$
1,075
 
 
The table below presents the activity within Level 3 of the fair value hierarchy for the six months ended June 30, 2014:

Fair Value Measurements Using Significant Unobservable Inputs (Level 3)
 
(in thousands)
 
Warrant
Liability
 
Beginning balance as of December 31, 2013
 
$
2,310
 
Total change in the fair value of the liability included in earnings, including warrant expirations
  
(1,092
)
Fair value of warrants exercised
  
(143
)
Ending balance as of June 30, 2014
 
$
1,075
XML 47 R16.htm IDEA: XBRL DOCUMENT v2.4.0.8
Taxes
6 Months Ended
Jun. 30, 2014
Taxes [Abstract]  
Taxes
(10)
Taxes

As discussed in Note 13 Income Taxes of the Company’s Annual Report, the Company has a valuation allowance against the full amount of its net deferred tax assets.   The Company currently provides a valuation allowance against deferred tax assets when it is more likely than not that some portion or all of its deferred tax assets will not be realized. The Company has not recognized any unrecognized tax benefits in its balance sheet.

The Company is subject to income tax in the U.S., as well as various state and international jurisdictions. The Company has not been audited by the U.S. Internal Revenue Service, international tax authorities, or any states in connection with income taxes. The Company’s New York State tax returns have been subject to annual desk reviews which have resulted in insignificant adjustments to the related franchise tax liabilities and credits. The Company’s tax years generally remain open to examination for all federal, state and foreign tax matters until its net operating loss carryforwards are utilized and the applicable statutes of limitation have expired. The federal and state tax authorities can generally reduce a net operating loss (but not create taxable income) for a period outside the statute of limitations in order to determine the correct amount of net operating loss which may be allowed as a deduction against income for a period within the statute of limitations.
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Stockholders Equity, Stock Incentive Plans (Details) (USD $)
6 Months Ended 12 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Dec. 31, 2013
Stock Options [Member]
     
Stock Options [Roll Forward]      
Outstanding at December 31, 2013 (in shares) 252,158    
Granted (in shares) 0    
Forfeited (in shares) (52,303)    
Expired (in shares) (625)    
Outstanding at June 30, 2014 (in shares) 199,230   252,158
Stock Options, Exercise Price per Share [Roll Forward]      
Granted (in dollars per share) $ 0    
Weighted Average Exercise Price [Roll Forward]      
Outstanding at December 31, 2013 (in dollars per share) $ 57.90    
Granted (in dollars per share) $ 0    
Forfeited (in dollars per share) $ 75.99    
Expired (in dollars per share) $ 58.56    
Outstanding at June 30, 2014 (in dollars per share) $ 53.16   $ 57.90
Weighted Average Remaining Life [Abstract]      
Weighted Average Remaining Life 7 years 0 months 29 days   7 years 4 months 10 days
Assumptions used to determine the fair value of stock options [Abstract]      
Dividend yield (in hundredths)   0.00%  
Weighted average volatility (in hundredths)   86.21%  
Expected life   6 years 9 months 18 days  
Stock Options [Member] | Minimum [Member]
     
Stock Options, Exercise Price per Share [Roll Forward]      
Outstanding at December 31, 2013 (in dollars per share) $ 4.80    
Forfeited (in dollars per share) $ 5.92    
Expired (in dollars per share) $ 58.56    
Outstanding at June 30, 2014 (in dollars per share) $ 4.80    
Assumptions used to determine the fair value of stock options [Abstract]      
Expected volatility (in hundredths)   86.16%  
Risk-free interest rates (in hundredths)   0.99%  
Stock Options [Member] | Maximum [Member]
     
Stock Options, Exercise Price per Share [Roll Forward]      
Outstanding at December 31, 2013 (in dollars per share) $ 248.64    
Forfeited (in dollars per share) $ 248.64    
Expired (in dollars per share) $ 58.56    
Outstanding at June 30, 2014 (in dollars per share) $ 248.64    
Assumptions used to determine the fair value of stock options [Abstract]      
Expected volatility (in hundredths)   93.68%  
Risk-free interest rates (in hundredths)   1.36%  
Restricted Stock [Member]
     
Restricted Stock [Roll Forward]      
Outstanding at December 31, 2013 (in shares) 20,347    
Granted (in shares) 0    
Vested (in shares) (17,233)    
Forfeited (in shares) (393)    
Outstanding at June 30, 2014 (in shares) 2,721    
Weighted Average Grant Date Fair Value [Roll Forward]      
Outstanding at December 31, 2013 (in dollars per share) $ 16.84    
Granted (in dollars per share) $ 0    
Vested (in dollars per share) $ 12.70    
Forfeited (in dollars per share) $ 38.24    
Outstanding at June 30, 2014 (in dollars per share) $ 39.98    
XML 49 R21.htm IDEA: XBRL DOCUMENT v2.4.0.8
Prepaid Expenses and Other Current Assets (Tables)
6 Months Ended
Jun. 30, 2014
Prepaid Expenses and Other Current Assets [Abstract]  
Prepaid expenses and other current assets
Prepaid expenses and other current assets consist of the following:

(in thousands)
 
June 30,
2014
  
December 31,
2013
 
Kits for clinical use
 
$
327
  
$
287
 
Insurance premiums
  
322
   
407
 
Professional fees
  
27
   
377
 
Income tax credits receivable
  
18
   
326
 
Other1
  
158
   
314
 
Total prepaid expenses and other current assets
 
$
852
  
$
1,711
 
 
1 Other consists of various prepaid expenses and other current assets with no individual item accounting for more than 5% of the total balance at June 30, 2014 and December 31, 2013.
XML 50 R26.htm IDEA: XBRL DOCUMENT v2.4.0.8
Fair Value Measurements (Tables)
6 Months Ended
Jun. 30, 2014
Fair Value Measurements [Abstract]  
Schedule of fair value of the warrants
The fair value of the warrants at June 30, 2014 was determined by using an option pricing model with the following assumptions:

 
 
2013
Warrants
  
2012
Warrants
 
Expected volatility
  
94.18%
  
111.35%
 
Risk-free interest rates
  
1.34%
 
  
0.11%
 
Expected life (in years)
  
4.33
   
0.92
 
Assets and liabilities measured at fair value on a recurring basis
The table below presents the Company’s assets and liabilities measured at fair value on a recurring basis as of June 30, 2014, aggregated by the level in the fair value hierarchy within which those measurements fall.

 
Assets and Liabilities Measured at Fair Value
on a Recurring Basis
 
(in thousands)
Level 1
 
Level 2
 
Level 3
 
Balance at
June 30, 2014
 
Assets
 
 
 
 
Money market funds
 
$
1,945
  
$
  
$
  
$
1,945
 
Liabilities
                
Warrant liability
 
$
  
$
  
$
1,075
  
$
1,075
 
Fair value measurements using significant unobservable inputs
The table below presents the activity within Level 3 of the fair value hierarchy for the six months ended June 30, 2014:

Fair Value Measurements Using Significant Unobservable Inputs (Level 3)
 
(in thousands)
 
Warrant
Liability
 
Beginning balance as of December 31, 2013
 
$
2,310
 
Total change in the fair value of the liability included in earnings, including warrant expirations
  
(1,092
)
Fair value of warrants exercised
  
(143
)
Ending balance as of June 30, 2014
 
$
1,075
 
XML 51 R5.htm IDEA: XBRL DOCUMENT v2.4.0.8
Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) (Parenthetical)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2013
Dec. 31, 2013
Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) [Abstract]        
Reverse stock split ratio one-for- sixteen (1:16) one-for- sixteen (1:16) one-for- sixteen (1:16) one-for- sixteen (1:16)
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Property, Plant, and Equipment
6 Months Ended
Jun. 30, 2014
Property, Plant, and Equipment [Abstract]  
Property, Plant, and Equipment
(4)Property, Plant, and Equipment

Property, plant, and equipment consist of the following:

(in thousands)
 
June 30,
2014
  
December 31,
2013
 
Enterprise hardware and software
 
$
2,009
  
$
2,143
 
Leaseholds
  
1,667
   
1,749
 
Equipment
  
1,421
   
1,552
 
Furniture
  
957
   
957
 
Buildings and land
  
603
   
603
 
Property, plant and equipment, gross
  
6,657
   
7,004
 
Accumulated depreciation
  
(4,236
)
  
(3,935
)
Property, plant and equipment, net
 
$
2,421
  
$
3,069
 

Depreciation expense for the three and six months ended June 30, 2014 was approximately $0.3 million and $0.5 million, respectively, as compared to approximately $0.3 million and $0.6 million for the same periods in 2013.
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Net Loss per Common Share (Tables)
6 Months Ended
Jun. 30, 2014
Net Loss per Common Share [Abstract]  
Calculation of net loss and number of shares used to compute basic and diluted earnings per share
The calculation of net loss and the number of shares used to compute basic and diluted earnings per share for the three and six month periods ended June 30, 2014 and 2013 are as follows:

 
 
Three months ended
June 30,
  
Six months ended
June 30,
 
(in thousands, except share data)
 
2014
  
2013
  
2014
  
2013
 
Net loss – basic
 
$
(4,600
)
 
$
(5,482
)
 
$
(9,878
)
 
$
(18,328
)
Adjustment for gain on warrant derivative liability
  
(356
)
  
   
(363
)
  
 
Net loss – diluted
 
$
(4,956
)
 
$
(5,482
)
 
$
(10,241
)
 
$
(18,328
)
 
                
Weighted average shares outstanding – basic
  
9,426,169
   
6,023,785
   
9,363,123
   
5,683,380
 
Adjustment for warrant exercises
  
54,764
   
   
99,594
   
 
Weighted average shares outstanding – diluted
  
9,480,933
   
6,023,785
   
9,462,717
   
5,683,380
 
 
                
Net loss per share – basic
 
$
(0.49
)
 
$
(0.91
)
 
$
(1.06
)
 
$
(3.22
)
Net loss per share – diluted
 
$
(0.52
)
 
$
(0.91
)
 
$
(1.08
)
 
$
(3.22
)
Anti-dilutive Securities Excluded from the Computation of Earnings per Share
The following potentially dilutive securities were excluded from the computation of earnings per share as of June 30, 2014 and 2013 because their effects would be anti-dilutive:

 
 
June 30,
 
 
 
2014
  
2013
 
Stock options
  
199,230
   
323,417
 
Unvested restricted shares
  
2,721
   
24,797
 
Warrants
  
589,500
   
339,994
 
Total
  
791,451
   
688,208
 
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Inventories (Tables)
6 Months Ended
Jun. 30, 2014
Inventories [Abstract]  
Schedule of inventories
Inventories consist of the following:

(in thousands)
 
June 30,
2014
  
December 31,
2013
 
Raw materials
 
$
196
  
$
249
 
Work-in-process
  
295
   
364
 
Finished goods
  
109
   
106
 
Total inventory
 
$
600
  
$
719