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Debt - Narrative (Details) - USD ($)
1 Months Ended 12 Months Ended
Aug. 31, 2020
Dec. 31, 2018
Dec. 31, 2021
Dec. 31, 2020
May 31, 2020
Bridge Facility | Common Stock Held By Sanofi | Bridge Loan          
Debt Instrument [Line Items]          
Debt, principle amount         $ 1,500,000,000
Line of credit | Senior unsecured revolving credit facility          
Debt Instrument [Line Items]          
Maximum borrowing capacity   $ 750,000,000      
Line of credit facility, expiration period   5 years      
Increase Limit   $ 250,000,000      
Borrowings outstanding     $ 0    
Line of credit | Letters of credit          
Debt Instrument [Line Items]          
Maximum borrowing capacity   $ 50,000,000      
Senior unsecured notes          
Debt Instrument [Line Items]          
Interest expense     $ 44,400,000 $ 17,600,000  
Redemption price, percentage 100.00%        
Redemption price with change-in-control provision, percentage 101.00%        
Senior unsecured notes | 1.750% Senior Notes due September 2030          
Debt Instrument [Line Items]          
Debt, principle amount $ 1,250,000,000        
Senior unsecured notes | 2.800% Senior Notes due September 2050          
Debt Instrument [Line Items]          
Debt, principle amount $ 750,000,000