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Collaboration, License, and Other Agreements - Amounts Recognized in Statement of Operations with Roche (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Disaggregation of Revenue [Line Items]      
Revenues $ 16,071.7 $ 8,497.1 $ 6,557.6
Roche Collaboration Agreement | Casirivimab and imdevimab | Collaboration revenue      
Disaggregation of Revenue [Line Items]      
Revenues 361.8 0.0  
Roche Collaboration Agreement | Casirivimab and imdevimab | Research and development expense      
Disaggregation of Revenue [Line Items]      
Revenues 128.1 78.5  
Roche Collaboration Agreement | Casirivimab and imdevimab | Cost of goods sold      
Disaggregation of Revenue [Line Items]      
Revenues $ 259.6 $ 0.0