Collaboration, License, and Other Agreements - Bayer Narrative (Details) - Bayer $ in Millions	12 Months Ended
	Dec. 31, 2021 USD ($)
Disaggregation of Revenue [Line Items]
Percentage of repayment of development balance out of profits	50.00%
Contingent reimbursement obligation	$ 282
Minimum
Disaggregation of Revenue [Line Items]
Revenue based on percentage of annual sales in Japan	33.50%
Maximum
Disaggregation of Revenue [Line Items]
Revenue based on percentage of annual sales in Japan	40.00%