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Collaboration, License, and Other Agreements - Schedule of Collaboration Revenue Earned From Sanofi (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Disaggregation of Revenue [Line Items]                      
Revenues $ 2,422.9 $ 2,294.0 $ 1,952.0 $ 1,828.2 $ 1,863.5 $ 1,743.7 $ 1,577.8 $ 1,372.6 $ 8,497.1 $ 6,557.6 $ 5,145.6
Product and service, other | Sanofi Collaboration Agreement, Antibody                      
Disaggregation of Revenue [Line Items]                      
Revenues                
Regeneron's share of profits (losses) in connection with commercialization of antibodies | Sanofi Collaboration Agreement, Antibody                      
Disaggregation of Revenue [Line Items]                      
Revenues                 785.2 209.3 (227.0)
Regeneron's share of profits (losses) in connection with commercialization of antibodies | Sanofi Collaboration Agreement, Immuno-oncology                      
Disaggregation of Revenue [Line Items]                      
Revenues                 (25.7) (21.7) (12.4)
Sales-based milestone earned | Sanofi Collaboration Agreement, Antibody                      
Disaggregation of Revenue [Line Items]                      
Revenues                 50.0 0.0 0.0
Reimbursement for manufacturing of commercial supplies | Sanofi Collaboration Agreement, Antibody                      
Disaggregation of Revenue [Line Items]                      
Revenues                 368.0 216.0 113.7
Reimbursement for manufacturing of commercial supplies | Sanofi Collaboration Agreement, Immuno-oncology                      
Disaggregation of Revenue [Line Items]                      
Revenues                 8.9 0.0 0.0
Reimbursement of research and development expenses | Sanofi Collaboration Agreement, Antibody                      
Disaggregation of Revenue [Line Items]                      
Revenues                 226.7 277.7 265.3
Reimbursement of research and development expenses | Sanofi Collaboration Agreement, Immuno-oncology                      
Disaggregation of Revenue [Line Items]                      
Revenues                 166.2 163.0 311.8
Regeneron's obligation for its share of Sanofi research and development expenses | Sanofi Collaboration Agreement, Antibody                      
Disaggregation of Revenue [Line Items]                      
Revenues                 (77.6) (46.0) (47.7)
Reimbursement of commercialization-related expenses | Sanofi Collaboration Agreement, Antibody                      
Disaggregation of Revenue [Line Items]                      
Revenues                 359.4 479.9 417.2
Reimbursement of commercialization-related expenses | Sanofi Collaboration Agreement, Immuno-oncology                      
Disaggregation of Revenue [Line Items]                      
Revenues                 64.7 10.3 8.9
Regeneron's obligation for its share of Sanofi other expenses | Sanofi Collaboration Agreement, Antibody                      
Disaggregation of Revenue [Line Items]                      
Revenues                 (21.5) (12.8) (16.1)
Regeneron's obligation for Sanofi's share of Libtayo U.S. gross profits | Sanofi Collaboration Agreement, Immuno-oncology                      
Disaggregation of Revenue [Line Items]                      
Revenues                 (119.1) (78.2) (6.8)
Amounts recognized in connection with up-front and development milestone payments received | Sanofi Collaboration Agreement, Immuno-oncology                      
Disaggregation of Revenue [Line Items]                      
Revenues                 $ 210.6 $ 92.7 $ 243.8