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Interim Financial Statements - Schedule of Statements of Operations Data (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues $ 2,294.0 $ 1,743.7 $ 6,074.2 $ 4,694.1
Research and development 684.6 526.0 1,990.5 1,897.6
Selling, general, and administrative 326.9 304.4 1,042.5 890.1
Other operating (income) expense, net (44.6) (50.7) (135.2) (171.1)
Total operating expenses 1,240.9 1,005.2 3,664.6 3,160.0
Collaboration and contract manufacturing        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Cost of collaboration and contract manufacturing 143.0 109.6 454.5 289.6
Sanofi | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 353.3 175.0 869.3 232.8
Bayer | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 299.9 293.6 825.5 834.8
Other | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues $ 158.6 36.8 $ 433.6 78.5
As Previously Reported        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   2,048.4   5,693.9
Research and development   663.4   2,353.5
Selling, general, and administrative   419.9   1,248.0
Other operating (income) expense, net   0.0   0.0
Total operating expenses   1,309.9   4,159.8
As Previously Reported | Collaboration and contract manufacturing        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Cost of collaboration and contract manufacturing   110.7   304.5
As Previously Reported | Sanofi | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   404.2   999.7
As Previously Reported | Bayer | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   302.8   868.0
As Previously Reported | Other | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   103.1   278.2
Adjustments        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   (304.7)   (999.8)
Research and development   (137.4)   (455.9)
Selling, general, and administrative   (115.5)   (357.9)
Other operating (income) expense, net   (50.7)   (171.1)
Total operating expenses   (304.7)   (999.8)
Adjustments | Collaboration and contract manufacturing        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Cost of collaboration and contract manufacturing   (1.1)   (14.9)
Adjustments | Sanofi | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   (229.2)   (766.9)
Adjustments | Bayer | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   (9.2)   (33.2)
Adjustments | Other | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   $ (66.3)   $ (199.7)