Revenue recognized in the period, inclusive of amounts recognized which were previously deferred.

No definition available.

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- Definition

The aggregate amount of additional payments the Company is entitled to receive upon the achievement of specified annual net sales amounts.

+ References

No definition available.

+ Details

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Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

The percentage of net sales of the product the Company will supply the product to MTPC (subject to adjustment in certain circumstances).

+ References

No definition available.

+ Details

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Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

The amount of contingent payments the Company is entitled to receive related to development and other milestones achieved by MTPC.

+ References

No definition available.

+ Details

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Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

Future Development Milestone Payment Companyis Eligible to Receive

+ References

No definition available.

+ Details

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Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

The starting specified levels of total annual sales within the MTPC Territories at which the Company is eligible to receive additional payments.

+ References

No definition available.

+ Details

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Definition

Amount of deferred revenue recognized for transactions arising during the current reporting period. Deferred revenue is a liability as of the balance sheet date related to a revenue producing activity for which revenue has not yet been recognized. Generally, an Entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 605
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB TOPIC 13.A.4(a).Q1)
-URI http://asc.fasb.org/extlink&oid=65893310&loc=d3e214044-122780

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 605
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB Topic 13.A.3)
-URI http://asc.fasb.org/extlink&oid=65893310&loc=d3e214044-122780

+ Details

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Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

The amount of consideration recognized during the period for the milestone or milestones.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 605
-SubTopic 28
-Section 50
-Paragraph 2
-Subparagraph (e)
-URI http://asc.fasb.org/extlink&oid=68058744&loc=SL6892177-166501

+ Details

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Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Details

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- Details

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- Details

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- Details

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- Details

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Collaboration Agreements (Mitsubishi Tanabe Pharma) (Details) - Mitsubishi Tanabe Pharma Corporation (MTPC) [Member] - Collaborative Arrangement [Member] - USD ($) $ in Millions	1 Months Ended	3 Months Ended			12 Months Ended
	Sep. 30, 2015	Dec. 31, 2017	Jun. 30, 2017	Mar. 31, 2016	Dec. 31, 2017	Dec. 31, 2016
Collaboration Agreements [Line Items]
Deferred Revenue, Additions	$ 10.0	$ 25.0
Collaboration revenue					$ 40.6	$ 14.4
Revenue Recognition, Milestone Method, Revenue Recognized			$ 30.0
Future development milestone payment the Company is eligible to receive					20.0
Contingent payments Company could receive					80.0
Collaborative Arrangement, Additional Eligible Aggregate Payments					100.0
Starting specified levels of annual sales at which sales milestone payments may be received					$ 200.0
Maximum
Collaboration Agreements [Line Items]
Collaborative Arrangement, Purchase Price, Percentage of Net Product Sales					50.00%
Minimum
Collaboration Agreements [Line Items]
Collaborative Arrangement, Purchase Price, Percentage of Net Product Sales					30.00%
Additional payments received [Member] [Member]
Collaboration Agreements [Line Items]
Deferred Revenue, Additions				$ 60.0