8-K

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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549



                                    FORM 8-K

                                 CURRENT REPORT


     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

                         Date of Report: April 13, 1999



                         Commission File Number: 0-18976


                          CELTRIX PHARMACEUTICALS, INC.
             (Exact name of registrant as specified in its charter)



         DELAWARE                                      94-3121462
   (State or other jurisdiction          (I.R.S. Employer Identification No.)
 of incorporation or organization)



           2033 Gateway Place, Suite 600, San Jose, CA 95110 (Address
                  of principal executive offices and zip code)


                  Registrant's Telephone Number: (408) 988-2500



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ITEM 5.    OTHER EVENTS

      On April 13, 1999, Celtrix Pharmaceuticals, Inc., a Delaware corporation
(the "Company") announced Celtrix Pharmaceuticals Forms Partnership with Elan
plc to Treat Osteoporosis. Further details regarding this announcement are
contained in the Company's news release dated April 13, 1999, attached as
exhibit hereto and incorporated by reference herein.

ITEM 7. FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS

(A)   EXHIBITS

Exhibit 21 Celtrix Pharmaceuticals, Inc. News Release dated April 13, 1999.





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                                   SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.




                            CELTRIX PHARMACEUTICALS, INC. (Registrant)


Date: April 13, 1999        By: /s/ DONALD D. HUFFMAN                         
                            ---------------------------------------------------
                            Donald D. Huffman
                            Vice President, Finance & Administration Chief
                            Financial Officer (Duly authorized principal
                            financial and accounting officer.)




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                          CELTRIX PHARMACEUTICALS, INC.
                                INDEX TO EXHIBITS




     Exhibit Number
     --------------
                                                    
     Exhibit 21       Celtrix Pharmaceuticals, Inc. Press Release
                      dated April 13, 1999.

EX-21

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                                                                      EXHIBIT 21

                              [CELTRIX LETTERHEAD]

NEWS RELEASE


                     CONTACT:      Andreas Sommer, Ph.D.
                                   President and Chief Executive Officer
                                   (408) 573-6263


  CELTRIX PHARMACEUTICALS FORMS PARTNERSHIP WITH ELAN PLC TO TREAT OSTEOPOROSIS

        PARTNERSHIP COMBINES SOMATOKINE(R) AND MEDIPAD(R) DELIVERY SYSTEM

        San JOSE, CA -- April 13, 1999 -- Celtrix Pharmaceuticals, Inc. (Nasdaq:
CTRX) announced today that it has established a joint venture with Elan
Corporation, plc (NYSE: ELN) for the development of SomatoKine(R) to treat
osteoporosis using Elan's MEDIPAD(R) Delivery System.

        "We are extremely pleased to announce a collaboration with the world's
leading drug delivery company," commented Andreas Sommer, Ph.D., Celtrix's
president and chief executive officer. "The collaboration provides the necessary
financial and technical resources to aggressively advance SomatoKine development
for the treatment of osteoporosis. It also allows Celtrix to retain at least one
half of the worldwide rights to this important indication."

        The joint venture will combine a promising drug with Elan's proprietary
micro-infusion device in addressing a multi-billion dollar worldwide market. The
terms of the agreement include Elan's purchase of up to $12.8 million in Celtrix
preferred stock at a price equivalent to $2.006 per share. Celtrix will use the
proceeds of the preferred stock sale to fund its share of the joint venture's
initial capitalization and research and development costs. Elan will commit
additional funds to the joint venture to support its operating costs.

        The joint venture is initially 80.1% owned by Celtrix and 19.9% by Elan
and Elan, at its option, has either the right to convert the preferred stock
into Celtrix common stock or exchange a portion of the preferred stock into
additional ownership in the new joint venture.

        The joint venture will pay a license fee to Elan for the use of the
MEDIPAD technology while Celtrix will have an 80% share in any future proceeds
related to the further development and commercialization of the osteoporosis
product (e.g. upfront payments, milestones or royalties) received by the joint
venture, regardless of ownership, until it is paid $10 million. Thereafter,
Celtrix and Elan will share the joint venture's proceeds in accordance with
their ownership interests. The joint venture is subject to regulatory clearance
and the execution of definitive agreements and is expected to close during the
second quarter of 1999.

        In a separate transaction, Celtrix announced Elan has agreed to purchase
$2.5 million of Celtrix common stock at a premium to the market price.

                                     -more-


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"Celtrix Pharmaceuticals Forms Partnership with Elan plc to Treat Osteoporosis"
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        In December 1998, Celtrix reported the final results of its Phase IIA
clinical feasibility trial using SomatoKine (IGF-I/BP3) in the treatment of
severely osteoporotic hip fracture patients. The data reveal significant
treatment results in several key measurements including hip bone mineral density
and tests of functional ability. Elan's MEDIPAD Delivery System offers a state
of the art, disposable micro-infusion pump, worn similar to a transdermal patch,
for administration of SomatoKine in this indication.

ADDITIONAL INFORMATION

        Celtrix is a biopharmaceutical company developing novel therapeutics for
seriously debilitating, degenerative conditions primarily associated with severe
trauma, chronic diseases or aging. The company's focus is on SomatoKine, a novel
IGF-BP3 complex, for treatment of a broad range of metabolic disorders. Celtrix
has completed Phase IIA clinical testing for the treatment of severe
osteoporosis (recovery from hip fracture), diabetes and traumatic burns. Other
potential indications include protein wasting diseases associated with cancer,
AIDS, advanced kidney failure and other life-threatening conditions.

        This news release contains certain forward-looking statements within the
meaning of Section 21 of the Securities Exchange Act of 1934, as amended. Actual
results may differ materially from the statements made, as a result of various
factors, including risks associated with the ability to complete the formation
of the joint venture and securities sales to Elan, obtaining additional funding
for further research in indications other than osteoporosis, continuation of the
same observations in future clinical trials involving SomatoKine, as well as
risks associated with the regulatory approval process, competitive products and
other factors which are listed from time to time in Celtrix's Securities and
Exchange Commission (SEC) filings. These forward-looking statements represent
Celtrix's judgment as of the date of this news release.

                                      -end-