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March 7, 2022



VIA ELECTRONIC TRANSMISSION
---------------------------

Securities and Exchange Commission
Division of Investment Management
100 F Street, NE
Washington, DC  20549

Re:     Pioneer Mid Cap Value Fund (the "Fund")
        File Nos. 033-34801 and 811-06106
        CIK No. 0000863334

Ladies and Gentlemen:

Pursuant to Rule 497(j) under the Securities Act of 1933, as amended, we
certify that the form of prospectus and statement of additional
information for the Fund, which would have been filed under paragraph (c)
of Rule 497, does not differ from that contained in Post-Effective
Amendment No. 56 to the Fund's registration statement on Form N-1A, filed
electronically on February 25, 2022 (Accession No. 0001193125-22-054288).

If you have any questions concerning the foregoing certification, please
contact me at (617) 422-4695.

Very truly yours,

/s/ Thomas Reyes
-------------------------
    Thomas Reyes
    Assistant Secretary


cc:     Christopher J. Kelley, Esq.
        Toby R. Serkin, Esq.




Amundi Asset Management US, Inc.
60 State Street
Boston, MA  02109-1820