Business Acquisition - Purchase price consideration (Details) - Aceragen $ in Thousands	3 Months Ended
Mar. 31, 2023 USD ($)
Business Acquisition
Total Consideration paid	$ 65,616
Stock options, restricted stock and warrants
Business Acquisition
Stock issued	5,822
Series Z convertible preferred stock \| Stock options, restricted stock and warrants
Business Acquisition
Stock issued	25,085
Series X preferred stock \| Stock options, restricted stock and warrants
Business Acquisition
Stock issued	31,900
Common Stock \| Stock options, restricted stock and warrants
Business Acquisition
Stock issued	$ 2,809

Amount of consideration transferred, consisting of acquisition-date fair value of assets transferred by the acquirer, liabilities incurred by the acquirer, and equity interest issued by the acquirer.

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
-SubTopic 30
-Section 30
-Paragraph 8
-URI https://asc.fasb.org/extlink&oid=126966197&loc=d3e6613-128477

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
-SubTopic 30
-Section 50
-Paragraph 1
-Subparagraph (b)
-URI https://asc.fasb.org/extlink&oid=126975305&loc=d3e6927-128479

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
-SubTopic 30
-Section 30
-Paragraph 7
-URI https://asc.fasb.org/extlink&oid=126966197&loc=d3e6578-128477

Name:	us-gaap_BusinessCombinationConsiderationTransferred1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration