Business Acquisition - Additional Information (Details) - USD ($)		3 Months Ended		9 Months Ended
	Sep. 28, 2022	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2021
Business Acquisition [Line Items]
Preferred stock, par value		$ 0.01		$ 0.01		$ 0.01
Acquisition-related costs		$ 2,836,000		$ 2,836,000
Nonrecurring pro forma transaction costs		7,800,000	$ 0	7,800,000	$ 0
Payment of success fee				3,400,000
Severance costs				800,000
Restructuring costs		2,802,000	$ 130,000	2,802,000	$ 1,322,000
Tax expense (benefit)		$ (6,039,000)		$ (6,039,000)
Series X preferred stock
Business Acquisition [Line Items]
Preferred stock, par value	$ 0.01
Aceragen
Business Acquisition [Line Items]
Acquisition-related costs	$ 2,800,000
Fair value of total consideration	$ 55,700,000
Aceragen | Merger Agreement
Business Acquisition [Line Items]
Outstanding security interests percentage	100.00%
Number of share acquisitions	4,398,762
Aceragen | Series Z convertible preferred stock | Merger Agreement
Business Acquisition [Line Items]
Shares issued during the acquisitions	$ 80,656
Conversion of common stock	1,000
Aceragen | Series X preferred stock | Merger Agreement
Business Acquisition [Line Items]
Number of share acquisitions	5