Net Income (Loss) per Common Share Applicable to Common Stockholders -Computation of basic and diluted net income per common share (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Net income (loss) applicable to common stockholders - Basic:
Net income (loss)	$ 98,091	$ (112,662)	$ (56,515)
Less: Deemed dividend on preferred stock			(28,043)
Less: Undistributed earnings to preferred stockholders	(1,150)
Net income (loss) applicable to common stockholders	96,941	(112,662)	(84,558)
Numerator for basic net income (loss) applicable to common stockholders	$ 96,941	$ (112,662)	$ (84,558)
Denominator for basic net income (loss) applicable to common stockholders	49,203	33,821	28,545
Net income (loss) income applicable to common stockholders - basic	$ 1.97	$ (3.33)	$ (2.96)
Net loss applicable to common stockholders - Diluted:
Net income (loss)	$ 96,941	$ (112,662)	$ (84,558)
Less: Warrant revaluation gain applicable to dilutive liability-classified warrants	(6,983)
Less: Future tranche right revaluation gain applicable to dilutive liability-classified future tranche rights	(118,803)
Numerator for diluted net income (loss) applicable to common stockholders	$ (28,845)	$ (112,662)	$ (84,558)
Denominator for basic net income (loss) applicable to common stockholders	49,203	33,821	28,545
Plus: Incremental shares underlying "in the money" warrants outstanding	93
Plus: Incremental shares underlying "in the money" liability-classified future tranche rights outstanding	831
Denominator for diluted net income (loss) applicable to common stockholders	50,127	33,821	28,545
Net income (loss) applicable to common stockholders - diluted	$ (0.58)	$ (3.33)	$ (2.96)