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Collaboration and License Agreements (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Apr. 30, 2019
USD ($)
Nov. 30, 2016
USD ($)
Nov. 30, 2015
USD ($)
person
Jun. 30, 2019
USD ($)
Jun. 30, 2018
USD ($)
Jun. 30, 2019
USD ($)
Jun. 30, 2018
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Alliance revenue       $ 1,448,000 $ 163,000 $ 1,448,000 $ 418,000
Option and License Agreement with Licensee              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Alliance revenue       1,400,000   1,400,000  
Transaction price           1,400,000  
Performance obligation       0   $ 0  
Percentage of shares acquired 10.00%         10.00%  
Option and License Agreement with Licensee | Other Assets              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Equity Securities without Readily Determinable Fair Value, Amount       100,000   $ 100,000  
Vivelix              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Alliance revenue       0   0  
Vivelix | Up-front Payment Arrangement              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Upfront payment received under collaboration agreement   $ 15,000,000          
Vivelix | Maximum              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Alliance revenue         100,000   100,000
GSK Agreement              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Number of development candidates | person     1        
Number of optional additional targets | person     2        
Deferred revenue recognized during the period       $ 0 $ 100,000 $ 0 $ 300,000
Research period     2 years     36 months  
GSK Agreement | Up-front Payment Arrangement              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Upfront payment received under collaboration agreement     $ 2,500,000        
GSK Agreement | License, Research, Clinical Development and Commercialization              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Milestone payments           $ 18,000,000  
GSK Agreement | Research and Development Plans and Designation of Development Candidates              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Milestone payments           1,000,000  
GSK Agreement | Clinical and Commercial Milestones              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Milestone payments           $ 17,000,000  
GSK Agreement | Maximum              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Maximum royalty percentage on net sales           5.00%  
IMO-9200 License | Option and License Agreement with Licensee              
Collaborative Arrangements and Non-collaborative Arrangement Transactions              
Upfront payment received under collaboration agreement $ 1,400,000            
Non-refundable fee upon exercise of option $ 1,000,000