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Stock-Based Compensation - Assumptions Used in Determining Fair Value of Stock Options (Details) - $ / shares
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Summary of Significant Accounting Policies    
Options to purchase common stock granted to employees and directors 4,116,800 3,422,000
Average risk free interest rate 2.10% 1.70%
Dividend rate 0.00% 0.00%
Expected lives (years) 3 years 9 months 18 days 3 years 10 months 24 days
Expected volatility 74.90% 86.90%
Weighted average exercise price of options granted during the period (per share) $ 2.24 $ 1.59