Subsequent Events (Details) $ / shares in Units, $ in Millions			1 Months Ended
	Nov. 01, 2017 shares	Oct. 30, 2017 USD ($) $ / shares shares	Oct. 31, 2017 USD ($) item shares	Sep. 30, 2017 shares	Dec. 31, 2016 shares
Subsequent Events
Shares purchased				149,680,000	149,065,000
Subsequent Events
Subsequent Events
Number of shares used in determining the authorized shares calculation			280,000,000
Number of times of actual reverse stock split ratio | item			2
Subsequent Events | Maximum
Subsequent Events
Reverse stock-split			0.125
Subsequent Events | Minimum
Subsequent Events
Reverse stock-split			0.25
Subsequent Events | Baker Bros. Advisors LP
Subsequent Events
Shares purchased		8,000,000
Shares held		18,306,757
Warrants to purchase shares		20,316,327
Warrant exercise price per share | $ / shares		$ 0.47
Subsequent Events | Baker Bros. Advisors LP | Pre-funded Warrants
Subsequent Events
Warrants to purchase shares		22,151,052
Warrant exercise price per share | $ / shares		$ 0.01
Subsequent Events | Pillar Invest Corporation
Subsequent Events
Issuance of shares from exercise of warrants			6,842,844
Total exercise price | $			$ 4.8
Underwriting
Subsequent Events
Shares issued	38,333,334
Share issue price per share | $ / shares		$ 1.50
Underwriting | Subsequent Events
Subsequent Events
Shares issued	5,000,000	33,333,334
Share issue price per share | $ / shares		$ 1.50
Gross proceeds | $		$ 50.0
Option to purchase additional shares duration	30 days
Net proceeds | $		$ 53.8