Income Taxes (Tables)

12 Months Ended

Dec. 31, 2016

Income Taxes

Schedule of components of deferred tax assets

	2016		2015
	(In thousands)
Operating loss carryforwards	$	56,832	$	46,432
Tax credit carryforwards		9,428		5,627
Other		7,710		5,698
		73,970		57,757
Valuation allowance		(73,970)		(57,757)
	$	—	$	—

Schedule of difference between U.S. federal corporate tax rate and Company effective tax rate

	2016		2015		2014
Expected federal income tax rate	(34.0)	%	(34.0)	%	(34.0)	%
Expiring credits and NOLs	—		—		—
Change in valuation allowance	42.2		39.8		(115.3)
Federal and state credits	(9.9)		(7.4)		(4.0)
State income taxes, net of federal benefit	(3.7)		(4.5)		(5.1)
Permanent differences	3.5		2.4		0.8
Section 382 limitation	—		—		157.5
Other	1.9		3.7		0.1
Effective tax rate	0.0	%	0.0	%	0.0	%