X0306 4 2014-05-21 0 0000861838 IDERA PHARMACEUTICALS, INC. IDRA 0001562070 Abdul-Wahab Umari C/O IDERA PHARMACEUTICALS, INC. 167 SIDNEY STREET CAMBRIDGE MA 02139 1 0 0 0 Common Stock 2014-05-21 4 S 0 250000 0.00 D 0 I See Footnotes Common Stock 2014-05-22 4 S 0 250000 0.00 D 0 I See Footnotes Common Stock 2014-05-23 4 S 0 45000 0.00 D 0 I See Footnotes Common Stock 2014-05-23 4 X 0 575758 0.00 A 0 I See Footnotes Common Stock 2014-05-23 4 X 0 313341 0.00 A 0 I See Footnotes Common Stock 2014-05-23 4 X 0 110901 0.00 A 0 I See Footnotes Warrants 0.79 2014-05-23 4 X 0 575758 0.00 D 2013-05-07 2014-06-01 Common Stock 575758 0 I See Footnotes Warrants 0.79 2014-05-23 4 X 0 313341 0.00 D 2013-05-07 2014-06-01 Common Stock 313341 0 I See Footnotes Warrants 0.79 2014-05-23 4 X 0 110901 0.00 D 2013-05-07 2014-06-01 Common Stock 110901 0 I See Footnotes Shares sold by Pillar Pharmaceuticals I, L.P. ("Pillar I"), of which Pillar Invest Corporation ("Pillar GP") is the general partner. Abdul-Wahab Umari is a director of Pillar GP and serves as the representative of a Pillar I, Pillar II and Pillar GP on the Issuer's board of directors. Mr. Umari disclaims Section 16 beneficial ownership of the Pillar I Warrants, Pillar II Warrants and the Besancon Warrants (including in each case the common stock underlying such warrants) and this report shall not be deemed an admission that he is the beneficial owners of any such securities, except to the extent of his pecuniary interest therein, if any, by virtue of his ownership interest in Pillar GP. As of the date hereof, Mr. Umari owns directly 67,304 shares of common stock of the Issuer. Warrants beneficially owned and exercised for shares of common stock by Pillar I, of which Pillar GP is the general partner (the "Pillar I Warrants"). Warrants beneficially owned and exercised for shares of common stock by Pillar Pharmaceuticals II, L.P. ("Pillar II"), of which Pillar GP is the general partner (the "Pillar II Warrants") of the Issuer. Warrants beneficially owned and exercised for shares of common stock by Participations Besancon, a fund advised by Pillar GP (the "Besancon Warrants"). /s/ Abdul-Wahab Umari 2014-05-23