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Organization - Additional Information (Detail) (USD $)
In Thousands, unless otherwise specified
9 Months Ended
Sep. 30, 2013
Dec. 31, 2012
Sep. 30, 2012
Dec. 31, 2011
Organization Consolidation And Presentation Of Financial Statements [Abstract]        
Cash and cash equivalents $ 38,749 $ 10,096 $ 8,352 $ 24,571
Accumulated deficit $ (406,794) $ (394,658)    
Quarter to which operations can be funded with current cash and cash equivalents Second quarter of 2015