X0306 4/A 2016-06-13 2016-06-15 0 0000861838 IDERA PHARMACEUTICALS, INC. IDRA 0001239746 GERAGHTY JAMES A C/O IDERA PHARMACEUTICALS, INC. 167 SIDNEY STREET CAMBRIDGE MA 02139 1 0 0 0 Stock Option 1.44 2016-06-13 4 A 0 52500 0 A 2026-06-13 Common Stock 52500 52500 D This amended form is being filed to correct a clerical error in the number of derivative securities reported in table II of the original filing. The number of derivative securities reported in the original filing was 52,000 while the actual number of options granted is 52,500. This option was automatically granted pursuant to the Company's director compensation program on the date of the Company's 2016 annual meeting of stockholders at an exercise price equal to the closing price of the Company's common stock on the date of the grant. The options vest with respect to one third of the underlying shares on the first anniversary of the date of grant and the balance of the underlying shares vest in eight equal quarterly installments following the first anniversary of the the date of the grant, subject to continued service as a director, and are granted under our 2013 Stock Incentive Plan. /s/ James A Geraghty 2016-06-28