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Note 2 - Going Concern and Liquidity (Details Textual) - USD ($)
1 Months Ended 3 Months Ended
Apr. 30, 2025
Mar. 31, 2025
Mar. 31, 2024
Dec. 31, 2024
Retained Earnings (Accumulated Deficit)   $ (130,047,692)   $ (128,053,106)
Operating Income (Loss)   (1,997,853) $ (1,465,068)  
Cash, Cash Equivalents, and Marketable Securities   2,200,000    
Working Capital   4,200,000    
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation   $ (1,008,089) $ (1,218,128)  
Mr. Neal Goldman, Ms. Benedetta Casamento, and Dr. Didier Demesmin [Member] | Promissory Note [Member] | Forecast [Member]        
Proceeds from Issuance of Debt $ 800,000