Note 7 - Patents - Summary of Patents (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Patents, cost	$ 1,377,863	$ 1,377,863
Patents, accumulated amortization	(1,127,013)	(1,100,244)
Patents-foundation intellectual property	250,850	277,619
Foundation Intellectual Property Patents [Member]
Patents, cost	1,377,863	1,377,863
Patents, accumulated amortization	(1,127,013)	(1,100,244)
Patents-foundation intellectual property	$ 250,850	$ 277,619

Accumulated amount of amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph (a)(1)
-URI https://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(16))
-URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

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Amount before amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 928
-SubTopic 340
-Section 50
-Paragraph 1
-URI https://asc.fasb.org/extlink&oid=6473545&loc=d3e61844-108004

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Amount after amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
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-SubTopic 20
-Section 50
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-URI https://asc.fasb.org/extlink&oid=120154696&loc=d3e54445-107959

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