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Note 2 - Liquidity and Uncertainties (Details Textual) - USD ($)
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Retained Earnings (Accumulated Deficit), Total $ (109,605,997)   $ (107,704,274)
Net Income (Loss) Attributable to Parent, Total $ (1,901,723) $ (972,869)