Note 2 - Liquidity and Uncertainties	3 Months Ended
Mar. 31, 2021
Notes to Financial Statements
Substantial Doubt about Going Concern [Text Block]	NOTE 2 - LIQUIDITY AND UNCERTAINTIES The Company has evaluated whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the Company's ability to continue as a going concern within one year after the date that the unaudited condensed consolidated financial statements are issued. As of March 31, 2021, the Company had an accumulated deficit of approximately $101,900,000 and has incurred a net loss of approximately $973,000 for the three month period ending March 31, 2021. In April and June of 2020, the Company completed Common Stock Offerings generating net proceeds of approximately $4.6 million and $13.4 million, respectively (see Note 9 ). As of March 31, 2021, cash on hand was approximately $16.9 million, an increase of $2.7 million from December 31, 2020. Management believes the Company has sufficient liquidity to support operations beyond a year after the unaudited condensed consolidated financial statements issue date. The coronavirus (COVID- 19 ) that was reported to have surfaced in Wuhan, China in December 2019 and that has now spread to other countries throughout the world has adversely impacted our operations and those of our third -party partners. As a result of the reduced hours and closings of dental offices throughout the country and the rest of the world due to the continuing spread of COVID- 19, revenues for the three months ended March 31, 2020 were adversely affected. Business interruptions, including any interruptions resulting from COVID- 19 could significantly disrupt our operations and could have a material adverse impact on our business. All of our employees are located in the U.S. In addition to our employees, we rely on (i) distributors, agents, and third -party logistics providers in connection with product sales and distribution and (ii) raw material and component suppliers in the U.S., Europe, and China. If we, or any of these third -party partners encounter any disruptions to our or their respective operations or facilities, or if we or any of these third -party partners were to shut down for any reason, including by fire, natural disaster, such as a hurricane, tornado or severe storm, power outage, systems failure, labor dispute, pandemic, or other unforeseen disruption, then we or they may be prevented or delayed from effectively operating our or their business, respectively. In addition, it is uncertain as to what effect the continuing spread of COVID- 19 will have on our commercialization efforts of our CompuFlo Epidural and CathCheck system as medical devices. Such future developments could have a material adverse effect on our financial results and our ability to conduct business as expected.

NOTE

- LIQUIDITY

AND UNCERTAINTIES

The Company has evaluated whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the Company's ability to continue as a going concern within

one

year after the date that the unaudited condensed consolidated financial statements are issued. As of

March

31,

2021,

the Company had an accumulated deficit of approximately

$101,900,000

and has incurred a net loss of approximately

$973,000

for the

three

month period ending

March 31, 2021.

April

and

June

2020,

the Company completed Common Stock Offerings generating net proceeds of approximately

$4.6

million and

$13.4

million, respectively (see Note

). As of

March 31, 2021,

cash on hand was approximately

$16.9

million, an increase of

$2.7

million from

December 31, 2020.

Management believes the Company has sufficient liquidity to support operations beyond a year after the unaudited condensed consolidated financial statements issue date.

The coronavirus (COVID-

) that was reported to have surfaced in Wuhan, China in

December 2019

and that has now spread to other countries throughout the world has adversely impacted our operations and those of our

third

-party partners. As a result of the reduced hours and closings of dental offices throughout the country and the rest of the world due to the continuing spread of COVID-

19,

revenues for the

three

months ended

March 31, 2020

were adversely affected. Business interruptions, including any interruptions resulting from COVID-

could significantly disrupt our operations and could have a material adverse impact on our business. All of our employees are located in the U.S.

In addition to our employees, we rely on (i) distributors, agents, and

third

-party logistics providers in connection with product sales and distribution and (ii) raw material and component suppliers in the U.S., Europe, and China. If we, or any of these

third

-party partners encounter any disruptions to our or their respective operations or facilities, or if we or any of these

third

-party partners were to shut down for any reason, including by fire, natural disaster, such as a hurricane, tornado or severe storm, power outage, systems failure, labor dispute, pandemic, or other unforeseen disruption, then we or they

may

be prevented or delayed from effectively operating our or their business, respectively.

In addition, it is uncertain as to what effect the continuing spread of COVID-

will have on our commercialization efforts of our CompuFlo Epidural and CathCheck system as medical devices. Such future developments could have a material adverse effect on our financial results and our ability to conduct business as expected.