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Note 9 - Stockholders' Equity (Details Textual) - USD ($)	1 Months Ended			3 Months Ended		12 Months Ended
	Jun. 30, 2020	Apr. 30, 2020	Jun. 30, 2011	Mar. 31, 2021	Mar. 31, 2020	Dec. 31, 2020	Dec. 31, 2019
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)				$ 2.14	$ 0.50	$ 1.49	$ 0.50
Deferred Compensation Arrangement with Individual, Shares Authorized for Issuance (in shares)				2,408,151	2,466,533	2,440,878	2,375,760
Share-based Payment Arrangement, Option [Member]
Share-based Payment Arrangement, Amount Capitalized				$ 113,507	$ 56,988
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total				$ 914,389
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Year)				2 years 255 days
Share-based Payment Arrangement, Option [Member] \| Share-based Payment Arrangement, Employee [Member]
Share Price (in dollars per share)				$ 3.11
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)				32,175
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate				1.42%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate				89.46%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term (Year)				3 years
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate				0.00%
Share-based Payment Arrangement, Option [Member] \| Share-based Payment Arrangement, Nonemployee [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)				16,666	8,333
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term (Year)				5 years
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate				0.00%
Share-based Payment Arrangement, Expense				$ 10,329	$ 0
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum				0.20%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum				1.41%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum				86.97%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum				89.90%
Share-based Payment Arrangement, Option [Member] \| Share-based Payment Arrangement, Nonemployee [Member] \| Minimum [Member]
Share Price (in dollars per share)				$ 3.57
Share-based Payment Arrangement, Option [Member] \| Share-based Payment Arrangement, Nonemployee [Member] \| Maximum [Member]
Share Price (in dollars per share)				$ 4.30
Stock Option Plan 2011 [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized (in shares)			2,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized (in shares)			4,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercise Period from Grant Date (Year)			3 years
Share-based Compensation Arrangement by Share-based Payment Award, Options, Expire Period after Grant Date (Year)			5 years
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant (in shares)				293,505		424,425
The 2020 Equity Incentive Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)				0		0
The 2020 Equity Incentive Plan [Member] \| Share-based Payment Arrangement, Option [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized (in shares)						2,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period (Year)						3 years
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)						5 years
Chief Executive Officer, Chief Financial Officer and Employees [Member]
Deferred Compensation Arrangement with Individual, Shares Authorized for Issuance (in shares)				2,264,127	2,306,698
Non-Employees [Member]
Common Stock, Capital Shares Reserved for Future Issuance (in shares)				144,024	159,835
Warrants Associated With April 2020 Public Offering [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)		2,710,000
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)		$ 1.20
Warrants and Rights Outstanding, Term (Year)		3 years
Warrants Associated With the June 2020 Public Offering [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	3,749,000
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)	$ 2.60
Warrants and Rights Outstanding, Term (Year)	3 years
April 6, 2020 Public Offering [Member]
Proceeds from Issuance of Common Stock, Gross		$ 5,100,000
Stock Issued During Period, Shares, New Issues (in shares)		5,420,000
Share Price (in dollars per share)		$ 0.95
June 30, 2020 Public Offering [Member]
Proceeds from Issuance of Common Stock, Gross	$ 14,600,000
Stock Issued During Period, Shares, New Issues (in shares)	6,770,000
Share Price (in dollars per share)	$ 2.15