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Note 7 - Patents (Tables)
 3 Months Ended
Mar. 31, 2021
Notes Tables  
Schedule of Finite-Lived Intangible Assets [Table Text Block]
   
March 31, 2021
  
   
Cost
    
Accumulated Amortization
    
Net
  
Patents-foundation intellectual property
   $
1,377,863
     $
(1,059,966
 )   $
317,897
  
Total
   $
1,377,863
     $
(1,059,966
 )   $
317,897
  
   
December 31, 2020
  
   
Cost
    
Accumulated Amortization
    
Net
  
Patents-foundation intellectual property
   $
1,377,863
     $
(1,048,614
 )   $
329,249
  
Total
   $
1,377,863
     $
(1,048,614
 )   $
329,249