Note 12 - Segment and Geographic Data - Summary by Reporting and Operating Segments (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017	Dec. 31, 2017
Product sales, net	$ 2,428,498	$ 2,523,750	$ 4,234,103	$ 6,212,738
Operating Income (Loss)	(1,424,687)	(1,552,435)	(3,426,340)	(2,078,374)
Depreciation and Amortization	245,127	31,845	510,118	66,387
Income before taxes and equity in earnings of affiliates:	(1,424,517)	(1,551,305)	(3,425,207)	(2,077,695)
Total assets	13,429,489		13,429,489		$ 15,628,787
Corporate, Non-Segment [Member]
Operating Income (Loss)	(1,301,607)	(1,645,922)	(2,952,043)	(2,823,167)
Depreciation and Amortization	238,546	20,826	482,519	41,540
Income before taxes and equity in earnings of affiliates:	(1,302,787)	(1,601,316)	(2,954,345)	(2,779,009)
Total assets	3,320,630		3,320,630		4,718,130
Dental Segment [Member] | Operating Segments [Member]
Product sales, net	2,388,898	2,523,750	4,158,003	6,212,738
Operating Income (Loss)	723,084	697,618	1,080,249	1,973,250
Depreciation and Amortization	4,103	4,458	8,244	8,926
Income before taxes and equity in earnings of affiliates:	725,007	699,737	1,084,829	1,975,836
Total assets	9,746,910		9,746,910		10,255,144
Medical Segment [Member] | Operating Segments [Member]
Product sales, net	39,600		76,100
Operating Income (Loss)	(846,164)	(604,131)	(1,554,546)	(1,228,457)
Depreciation and Amortization	2,478	6,561	19,355	15,921
Income before taxes and equity in earnings of affiliates:	(846,737)	$ (649,726)	(1,555,691)	$ (1,274,522)
Total assets	$ 361,949		$ 361,949		$ 655,513