[GRAPHIC OMITTED]
                                    MILESTONE
                                   SCIENTIFIC


September 30, 2005

Design Center, Inc.
218 Dew Drop Road
York, PA 17402
Attn:  Gary De Bruin


                   Re: MILESTONE SCIENTIFIC INC. ("MILESTONE")


Dear Mr. De Bruin,

         This will confirm that Milestone has agreed to issue to Design Center,
Inc. and that Design Center, Inc. has agreed to accept from Milestone 13,181
shares of common stock in payment of $25,176 as consideration for services
rendered to Milestone.

         By signing this letter, you confirm that (i) you are an "accredited
investor" within the meaning of Rule 215 of the Rules and Regulations under the
Securities Act, and (ii) you have acquired the shares for investment and
acknowledge that the shares cannot be resold or otherwise disposed of until they
are registered under the Securities Act and any applicable state securities laws
or an exemption from registration is available.

         Since the shares will not be registered at the time of issuance, the
certificates representing the shares delivered to you will bear the following
legend:


         THE SHARES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED
UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), AND MAY NOT BE SOLD,
TRANSFERRED, HYPOTHECATED OR ASSIGNED EXCEPT PURSUANT TO AN EFFECTIVE
REGISTRATION STATEMENT UNDER THE ACT OR IN A TRANSACTION WHICH IS EXEMPT FROM
REGISTRATION UNDER THE ACT.



         Please acknowledge your agreement and understanding of the above
provisions by signing and dating a copy of this letter and returning it to us by
facsimile and mail. The shares will be delivered to you promptly after receipt
of your acknowledgement.





                                                     Very truly yours,


                                                     MILESTONE SCIENTIFIC INC.


                                                     By: /s/ Rosaline Shau
                                                        ----------------------
                                                        Rosaline Shau
                                                        Chief Financial Officer



ACCEPTED AND AGREED TO
THIS 30th DAY OF SEPTEMBER, 2005


Design Centre, Inc.



/s/ Gary De Bruin
---------------------
By:  Gary De Bruin
Its: Senior Vice President


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          220 South Orange Avenue, Livingston, NJ  07039 o Tel: 973.535.2717 o
                                Fax: 973.535.2829
                                 www.MileSci.com