CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Cash flows from operating activities:
Net loss	$ (14,514)	$ (163,921)
Adjustments to reconcile net loss to net cash used for operating activities:
Non-cash royalty revenue related to sale of future royalties	(8,494)	(9,027)
Non-cash interest expense on liability related to sale of future royalties and convertible senior notes	2,691	3,194
Non-cash interest expense on amortization of debt discount and issuance costs	295
Depreciation and amortization	1,298	1,355
Stock and deferred share unit compensation	22,374	14,862
Change in operating assets and liabilities:
Accounts receivable	(118,098)	4,425
Unbilled receivable	(1,495)	1,649
Inventory	(17,572)
Contract asset		3,000
Prepaid and other current assets	(7,707)	(9,392)
Operating lease right-of-use assets	1,893	1,583
Other assets	(148)	(4,389)
Accounts payable	(20,395)	1,689
Accrued compensation	4,044	3,152
Other accrued liabilities	7,472	23,057
Deferred revenue	13,693	(38,257)
Operating lease liability	(3,027)	(2,583)
Net cash used for operating activities	(137,690)	(169,603)
Cash flows from investing activities:
Purchases of property and equipment	(1,641)	(1,116)
Net cash used for investing activities	(1,641)	(1,116)
Cash flows from financing activities:
Proceeds from issuance of common stock under stock plans	47,111	1,480
Proceeds from term loan, net of $3,182 of issuance costs	71,818
Proceeds from common stock issuance, net of $526 of transaction costs	350,799
Net cash provided by financing activities	469,728	1,480
Net change in cash and cash equivalents	330,397	(169,239)
Cash and cash equivalents, beginning of period	275,138	478,750
Cash and cash equivalents, end of period	605,535	$ 309,511
Supplemental cash flow information:
Cash paid during the year for interest	4,857
Cash paid during the year for taxes	$ 1,361