Capital Stock (Details) $ / shares in Units, $ in Thousands		1 Months Ended	3 Months Ended	9 Months Ended
	May 01, 2023 $ / shares shares	Jun. 30, 2023 shares	Sep. 30, 2023 $ / shares shares	Sep. 30, 2023 USD ($) $ / shares shares	Sep. 30, 2022 USD ($) shares	Dec. 31, 2022 shares	Dec. 31, 2021 $ / shares shares	Aug. 11, 2021	Jun. 30, 2018 shares
Stock-based compensation disclosure
Proceeds from issuance of common stock under stock plans | $				$ 47,111	$ 1,480
Common stock, issued shares			265,842,000	265,842,000		226,046,000
Stock received in exchange			21,853,000	21,853,000
Preferred stock, par value (in dollars per share) | $ / shares	$ 0.01		$ 0.01	$ 0.01
Conversion of stock ratio				1,000
Conversion Blocker			9.99	9.99
Maximum amount of increase or decrease to Conversion Blocker			19.99	19.99
Liquidation preference per share | $ / shares			$ 0.001	$ 0.001
ESPP
Stock-based compensation disclosure
Aggregate number of common shares reserved for future issuance									2,000,000
Series A Convertible Preferred Stock
Stock-based compensation disclosure
Stock exchanged	21,853
Common Stock
Stock-based compensation disclosure
Stock received in exchange	21,853,000
Pre-Funded Warrants
Stock-based compensation disclosure
Warrant exercise price | $ / shares							$ 0.01
Threshold percentage of common stock owned that limits the number of warrants exercised								9.99
Maximum percentage of increase or decrease to amount of common stock owned								19.99
RA Capital Healthcare Fund, L.P. | Pre-Funded Warrants
Stock-based compensation disclosure
Warrants exercised (in shares)				11,000,000
RA Capital Healthcare Fund, L.P. | Pre-Funded Warrants | Common Stock
Stock-based compensation disclosure
Common stock, issued shares			10,992,330	10,992,330
Redmile Group LLC | Pre-Funded Warrants
Stock-based compensation disclosure
Warrants exercised (in shares)		11,357,272
Stock options
Stock-based compensation disclosure
Stock options granted to directors (in shares)				6,316,000
Options exercised (in shares)				9,121,000
Securities Purchase Agreement | RA Capital Healthcare Fund, L.P. | Pre-Funded Warrants
Stock-based compensation disclosure
Pre-Funded warrants issued to purchase shares			21,434,872	21,434,872			21,434,782
Securities Purchase Agreement | Redmile Group LLC | Pre-Funded Warrants
Stock-based compensation disclosure
Pre-Funded warrants issued to purchase shares							11,363,636
Compensation Policy for Non-Employee Directors | Common Stock
Stock-based compensation disclosure
Share-based Compensation Arrangement by Share-based Payment Award, Shares Issued in Period				14,112
Compensation Policy for Non-Employee Directors | Stock options
Stock-based compensation disclosure
Stock options granted to directors (in shares)				157,000	322,000
Compensation Policy for Non-Employee Directors | Restricted stock units
Stock-based compensation disclosure
Stock options granted to directors (in shares)		105,000