Collaboration and License Agreements - Roche (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Collaborative Agreements disclosures
Revenue from contract with customer	$ 113,425	$ 15,375	$ 246,447	$ 67,615
Non-cash royalty revenue related to sale of future royalties			(8,494)	(9,027)
License and milestone fees
Collaborative Agreements disclosures
Revenue from contract with customer	$ 51	$ 7,382	$ 15,122	45,247
Roche
Collaborative Agreements disclosures
Period in arrears to receive royalty reports and payments related to sales of kadcyla			3 months
Roche | KADCYLA
Collaborative Agreements disclosures
Non-cash royalty revenue related to sale of future royalties			$ (17,900)	$ (21,500)