Collaboration and License Agreements - Roche (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Collaborative Agreements disclosures
Revenue from contract with customer	$ 83,153	$ 14,162	$ 133,022	$ 52,240
Non-cash royalty revenue related to sale of future royalties			(5,036)	(5,590)
License and milestone fees
Collaborative Agreements disclosures
Revenue from contract with customer	$ 40	$ 6,973	$ 15,071	37,865
Roche
Collaborative Agreements disclosures
Period in arrears to receive royalty reports and payments related to sales of kadcyla			3 months
Roche | KADCYLA
Collaborative Agreements disclosures
Non-cash royalty revenue related to sale of future royalties			$ (10,600)	$ (13,500)