CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2021
Revenues:
Total revenues	$ 83,153	$ 14,162	$ 133,022	$ 52,240
Cost and operating expenses:
Cost of sales	909		1,535
Research and development	50,077	51,422	101,697	95,704
Selling, general and administrative	36,356	23,793	76,372	40,441
Total cost and operating expenses	87,342	75,215	179,604	136,145
Loss from operations	(4,189)	(61,053)	(46,582)	(83,905)
Interest income	5,223	590	7,392	644
Interest expense on term loan	(3,318)		(3,318)
Non-cash interest expense on liability related to the sale of future royalties and term loan	(1,079)	(1,078)	(1,932)	(2,327)
Other (expense) income, net	(8)	(480)	55	(578)
Net loss before income taxes	(3,371)	(62,021)	(44,385)	(86,166)
Income tax expense	877		877
Net loss	$ (4,248)	$ (62,021)	$ (45,262)	$ (86,166)
Basic net loss per common share	$ (0.02)	$ (0.24)	$ (0.17)	$ (0.34)
Diluted net loss per common share				$ (0.34)	$ (0.32)
Basic weighted average common shares outstanding (in shares)	263,446	253,336	261,160	253,263
Diluted weighted average common shares outstanding (in shares)				253,263	199,365
License and milestone fees
Revenues:
Total revenues	$ 40	$ 6,973	$ 15,071	$ 37,865
Non-cash royalty revenue related to the sale of future royalties
Revenues:
Total revenues	5,742	7,116	10,581	13,544
Research and development support
Revenues:
Total revenues		$ 73	455	$ 831
Product revenue, net
Revenues:
Total revenues	$ 77,371		$ 106,915