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Product Revenue Reserves and Allowances (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Product Revenue Reserves and Allowances    
Beginning balance at January 1 $ 313  
Provision related to sales in the current period 4,144  
Credits and payments made (1,533)  
Ending balance at December 31 2,924  
Revenue from contract with customer 49,869 $ 38,078
Product revenue, net    
Product Revenue Reserves and Allowances    
Revenue from contract with customer $ 29,544