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Summary of Significant Accounting Policies - Computation of Net Loss per Common Share (Details) - shares
shares in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Computation of Net Loss per Common Share    
Options outstanding to purchase common stock, shares issuable under the employee stock purchase plan, and unvested restricted stock/units at end of period 39,064 27,012
Common stock equivalents under treasury stock method for options, shares issuable under the employee stock purchase plan, and unvested restricted stock/units 1,098 1,981