CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
ASSETS
Cash and cash equivalents	$ 275,138	$ 478,750
Accounts receivable	12,596	4,467
Unbilled receivable	1,531	2,345
Contract assets	0	3,000
Non-cash royalty receivable	3,851	4,115
Prepaid and other current assets	11,005	7,322
Total current assets	304,121	499,999
Property and equipment, net of accumulated depreciation	4,377	4,663
Operating lease right-of-use assets	10,231	12,392
Long-term inventory	16,196
Other assets	14,011	8,711
Total assets	348,936	525,765
LIABILITIES AND SHAREHOLDERS' EQUITY
Accounts payable	45,353	18,434
Accrued compensation	11,111	5,469
Other accrued liabilities	38,783	23,077
Current portion of liability related to the sale of future royalties, net of deferred financing costs of $162 and $198, respectively	8,659	6,077
Current portion of operating lease liability	4,096	3,537
Current portion of deferred revenue	13,856	44,351
Total current liabilities	121,858	100,945
Deferred revenue, net of current portion	36,355	47,717
Operating lease liability, net of current portion	11,148	15,244
Liability related to the sale of future royalties, net of current portion and deferred financing costs of $205 and $381, respectively	23,449	34,967
Other long-term liabilities	300	1,306
Total liabilities	193,110	200,179
Commitments and contingencies (Note L)
Shareholders' equity:
Preferred stock, $.01 par value; authorized 5,000 shares; no shares issued and outstanding as of each of December 31, 2022 and 2021
Common stock, $.01 par value; authorized 600,000 shares; 226,046 and 220,361 shares issued and outstanding as of December 31, 2022 and 2021, respectively	2,260	2,204
Additional paid-in capital	1,847,638	1,794,525
Accumulated deficit	(1,694,072)	(1,471,143)
Total shareholders' equity	155,826	325,586
Total liabilities and shareholders' equity	$ 348,936	$ 525,765