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Capital Stock (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 9 Months Ended
Aug. 11, 2021
USD ($)
$ / shares
shares
Dec. 09, 2016
Dec. 31, 2021
USD ($)
$ / shares
shares
Sep. 30, 2022
USD ($)
shares
Sep. 30, 2021
USD ($)
shares
Stock-based compensation disclosure          
Proceeds from issuance of common stock under stock plans | $       $ 1,480 $ 2,032
Exercise price | $ / shares     $ 6.60    
Warrant exercise price | $ / shares     0.01    
Pre-Funded Warrants          
Stock-based compensation disclosure          
Exercise price | $ / shares     $ 6.59    
Threshold percentage of common stock owned that limits the number of warrants exercised 9.99        
Maximum percentage upon at least 61 days prior notice from the investor to the Company 19.99        
RA Capital Healthcare Fund, L.P. | Pre-Funded Warrants          
Stock-based compensation disclosure          
Pre-Funded warrants issued to purchase shares | shares     16,000,000    
Redmile Group LLC | Pre-Funded Warrants          
Stock-based compensation disclosure          
Pre-Funded warrants issued to purchase shares | shares     11,363,636    
Stock options          
Stock-based compensation disclosure          
Stock options granted to directors (in shares) | shares       11,290,000  
Securities Purchase Agreement | Pre-Funded Warrants          
Stock-based compensation disclosure          
Proceeds from issuance of common stock under stock plans | $     $ 169,300    
Securities Purchase Agreement | RA Capital Healthcare Fund, L.P. | Pre-Funded Warrants          
Stock-based compensation disclosure          
Pre-Funded warrants issued to purchase shares | shares 5,434,782        
Exercise price | $ / shares $ 5.51        
Warrant exercise price | $ / shares $ 0.01        
Aggregate gross proceeds | $ $ 29,700        
Compensation Policy for Non-Employee Directors | Stock options          
Stock-based compensation disclosure          
Stock options granted to directors (in shares) | shares       322,000 352,000
Non-employee directors-initial grant | Deferred share units          
Stock-based compensation disclosure          
Vesting period   3 years      
Non-employee directors-first anniversary | Deferred share units          
Stock-based compensation disclosure          
Vesting period   1 year