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Agreements - Lilly (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Feb. 28, 2022
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Aug. 31, 2022
Dec. 31, 2021
Collaborative Agreements disclosures              
Aggregate amount of transaction price allocated to remaining performance obligations   $ 53,800   $ 53,800      
Revenue from contract with customer   15,375 $ 9,210 67,615 $ 41,864    
Amount of obligation included in long-term deferred revenue   38,732   38,732     $ 47,717
Additional targets              
Collaborative Agreements disclosures              
License agreement upfront payment receivable   6,500   6,500   $ 6,500  
Lilly              
Collaborative Agreements disclosures              
License agreement upfront payment receivable $ 13,000            
License agreement additional payment receivable 26,000            
License agreement, target selection fees and development, regulatory and commercial milestone payments receivable 1,700,000            
Aggregate amount of transaction price allocated to remaining performance obligations 13,000            
Lilly | Upfront payment              
Collaborative Agreements disclosures              
Estimated payments to received 13,000            
Lilly | Initial targets              
Collaborative Agreements disclosures              
Revenue from contract with customer 9,200     13,800      
Lilly | Additional targets              
Collaborative Agreements disclosures              
Revenue from contract with customer       4,600      
Lilly | Material rights to obtain licenses to replacement targets              
Collaborative Agreements disclosures              
Revenue from contract with customer $ 3,800            
Amount of obligation included in long-term deferred revenue   $ 5,700   5,700      
Lilly | Material rights to obtain additional target licenses to replacement targets              
Collaborative Agreements disclosures              
Revenue from contract with customer       $ 1,900