CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenues:
Total revenues	$ 14,162	$ 16,948	$ 52,240	$ 32,654
Operating expenses:
Research and development	51,422	34,589	95,704	69,002
Selling, general and administrative	23,793	9,728	40,441	19,937
Total operating expenses	75,215	44,317	136,145	88,939
Loss from operations	(61,053)	(27,369)	(83,905)	(56,285)
Investment income, net	590	11	644	24
Non-cash interest expense on liability related to the sale of future royalties and convertible senior notes	(1,078)	(3,557)	(2,327)	(8,201)
Interest expense on convertible senior notes		(23)		(47)
Other (expense) income, net	(480)	197	(578)	(283)
Net loss	$ (62,021)	$ (30,741)	$ (86,166)	$ (64,792)
Basic net loss per common share	$ (0.24)	$ (0.15)	$ (0.34)	$ (0.32)
Diluted net loss per common share	$ (0.24)	$ (0.15)	$ (0.34)	$ (0.32)
Basic weighted average common shares outstanding (in shares)	253,336	199,890	253,263	199,365
Diluted weighted average common shares outstanding (in shares)	253,336	199,890	253,263	199,365
Total comprehensive loss	$ (62,021)	$ (30,741)	$ (86,166)	$ (64,792)
License and milestone fees
Revenues:
Total revenues	6,973	252	37,865	409
Non-cash royalty revenue related to the sale of future royalties
Revenues:
Total revenues	7,116	16,690	13,544	32,235
Research and development support
Revenues:
Total revenues	$ 73	$ 6	$ 831	$ 10