CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
ASSETS
Cash and cash equivalents	$ 373,874	$ 478,750
Accounts receivable	909	4,467
Unbilled receivable	1,874	2,345
Contract assets		3,000
Non-cash royalty receivable	3,168	4,115
Prepaid and other current assets	14,099	7,322
Total current assets	393,924	499,999
Property and equipment, net of accumulated depreciation	4,334	4,663
Operating lease right-of-use assets	11,361	12,392
Other assets	12,676	8,711
Total assets	422,295	525,765
LIABILITIES AND SHAREHOLDERS' EQUITY
Accounts payable	17,245	18,434
Accrued compensation	4,960	5,469
Other accrued liabilities	36,588	23,077
Current portion of liability related to the sale of future royalties, net of deferred financing costs of $187 and $198, respectively	8,772	6,077
Current portion of operating lease liability	3,870	3,537
Current portion of deferred revenue	15,636	44,351
Total current liabilities	87,071	100,945
Deferred revenue, net of current portion	43,611	47,717
Operating lease liability, net of current portion	13,254	15,244
Liability related to the sale of future royalties, net of current portion and deferred financing costs of $282 and $381, respectively	28,062	34,967
Other long-term liabilities	466	1,306
Total liabilities	172,464	200,179
Commitments and contingencies (Note H)
Shareholders' equity:
Preferred stock, $.01 par value; authorized 5,000 shares; no shares issued and outstanding as of each of June 30, 2022 and December 31, 2021
Common stock, $.01 par value; authorized 600,000 shares; 220,644 and 220,361 shares issued and outstanding as of June 30, 2022 and December 31, 2021, respectively	2,206	2,204
Additional paid-in capital	1,804,934	1,794,525
Accumulated deficit	(1,557,309)	(1,471,143)
Total shareholders' equity	249,831	325,586
Total liabilities and shareholders' equity	$ 422,295	$ 525,765