CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Revenues:
Total revenues	$ 38,078	$ 15,706
Operating expenses:
Research and development	44,282	34,413
Selling, general and administrative	16,648	10,209
Total operating expenses	60,930	44,622
Loss from operations	(22,852)	(28,916)
Investment income, net	54	13
Non-cash interest expense on liability related to the sale of future royalties and convertible senior notes	(1,249)	(4,644)
Interest expense on convertible senior notes		(24)
Other expense, net	(98)	(480)
Net loss	$ (24,145)	$ (34,051)
Basic net loss per common share	$ (0.10)	$ (0.17)
Diluted net loss per common share	$ (0.10)	$ (0.17)
Basic weighted average common shares outstanding (in shares)	253,263	198,835
Diluted weighted average common shares outstanding (in shares)	253,263	198,835
Total comprehensive loss	$ (24,145)	$ (34,051)
License and milestone fees
Revenues:
Total revenues	30,892	157
Non-cash royalty revenue related to the sale of future royalties
Revenues:
Total revenues	6,428	15,545
Research and development support
Revenues:
Total revenues	$ 758	$ 4