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Nature of Business and Plan of Operations (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Net loss $ (24,145) $ (34,051)  
Accumulated deficit (1,495,288)   $ (1,471,143)
Total revenues 38,078 $ 15,706  
Cash and cash equivalents $ 437,661   $ 478,750
Number of months Capital resources meets capital expenditures 12 months    
Product      
Total revenues $ 0