CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
ASSETS
Cash and cash equivalents	$ 245,761	$ 293,856
Accounts receivable	221	35
Unbilled receivables	4,706	11
Contract assets	2,500
Non-cash royalty receivable	3,369	22,451
Prepaid and other current assets	14,330	7,901
Total current assets	270,887	324,254
Property and equipment, net of accumulated depreciation	4,636	5,760
Operating lease right-of-use assets	12,745	14,072
Other assets	8,535	10,986
Total assets	296,803	355,072
LIABILITIES AND SHAREHOLDERS' EQUITY
Accounts payable	10,520	9,538
Accrued compensation	4,718	4,620
Other accrued liabilities	34,718	29,320
Convertible 4.5% senior notes, net of deferred financing costs of $0 and $7, respectively		2,093
Current portion of liability related to the sale of future royalties, net of deferred financing costs of $206 and $319, respectively	4,945	44,357
Current portion of operating lease liability	3,358	3,146
Current portion of deferred revenue	53,526	29,249
Total current liabilities	111,785	122,323
Deferred revenue, net of current portion	52,479	80,860
Operating lease liability, net of current portion	16,045	18,651
Liability related to the sale of future royalties, net of current portion and deferred financing costs of $427 and $584, respectively	37,322	41,082
Other long-term liabilities	2,079	2,586
Total liabilities	219,710	265,502
Commitments and contingencies (Note I)
Shareholders' deficit:
Preferred stock, $.01 par value; authorized 5,000 shares; no shares issued and outstanding as of each of September 30, 2021 and December 31, 2020
Common stock, $.01 par value; authorized 300,000 shares; issued and outstanding 202,443 and 194,998 shares as of September 30, 2021 and December 31, 2020, respectively	2,024	1,950
Additional paid-in capital	1,509,040	1,419,460
Accumulated deficit	(1,433,971)	(1,331,840)
Total shareholders' equity	77,093	89,570
Total liabilities and shareholders' equity	$ 296,803	$ 355,072