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Summary of Significant Accounting Policies - Contract Balances from Contracts with Customers - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Dec. 31, 2019
Dec. 31, 2018
Revenue recognized in the period from:            
Revenue from contract with customer $ 18,189 $ 13,281 $ 46,501 $ 37,407    
Deferred revenue 130,526 145,852 130,526 145,852 $ 127,432 $ 80,802
Contract assets         3,631 $ 500
Contract liability 3,985   3,985   309  
Contract Liabilities, Impact Of Netting 4,369   4,369      
Revenue previously deferred 72 79 1,300 237    
Milestone earned, included in accounts receivable     8,000 500    
Probable milestone earned and paid       0    
License and milestone fees            
Revenue recognized in the period from:            
Revenue from contract with customer $ 97 79 1,325 5,237    
Genentech | Regulatory milestones            
Revenue recognized in the period from:            
Revenue previously deferred       5,000    
CytomX | License and milestone fees            
Revenue recognized in the period from:            
Revenue previously deferred     200      
CytomX | Probable Milestone            
Revenue recognized in the period from:            
Contract assets         3,600  
Contract liability         $ 4,400  
Kadcyla | Royalty revenue            
Revenue recognized in the period from:            
Deferred revenue   65,200   65,200    
Takeda | Technological Improvements            
Revenue recognized in the period from:            
Amortization of deferred revenue     900      
Fusion Pharmaceuticals | Probable Milestone            
Revenue recognized in the period from:            
Contract assets   $ 500   500    
Other Collaborators | Technological Improvements            
Revenue recognized in the period from:            
Amortization of deferred revenue     $ 1,100 $ 200