Represents the number of licenses terminated.

No definition available.

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- Definition

Represents the number of single-target licenses the company has right to use.

+ References

No definition available.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable, classified as noncurrent.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
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- Definition

The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

+ References

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-Publisher FASB
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Amount, including tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value-added and excise.

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Agreements - Lilly (Details)	1 Months Ended	3 Months Ended												12 Months Ended
Agreements - Lilly (Details)	Oct. 31, 2018 item	Dec. 31, 2019 USD ($)	Sep. 30, 2019 USD ($)	Jun. 30, 2019 USD ($)	Mar. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)	Sep. 30, 2018 USD ($)	Jun. 30, 2018 USD ($)	Mar. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)	Sep. 30, 2017 USD ($)	Jun. 30, 2017 USD ($)	Mar. 31, 2017 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)	Dec. 31, 2014 USD ($)	Dec. 31, 2013 USD ($)	Dec. 31, 2011 USD ($) item
Collaborative Agreements disclosures
Revenue from contract with customer		$ 44,864,000	$ 13,281,000	$ 15,542,000	$ 8,584,000	$ 13,416,000	$ 10,928,000	$ 9,287,000	$ 19,815,000	$ 39,448,000	$ 8,480,000	$ 39,020,000	$ 28,499,000	$ 82,271,000	$ 53,446,000	$ 115,447,000
Remaining arrangement consideration to be recognized as license revenue		127,123,000				80,485,000								127,123,000	80,485,000
Expense related to excess inventory		26,055,000	21,015,000	28,559,000	38,893,000	43,681,000	47,243,000	38,701,000	44,831,000	39,843,000	31,689,000	35,319,000	32,888,000	114,522,000	174,456,000	139,739,000
Lilly
Collaborative Agreements disclosures
Number of development and commercialization licenses \| item																			3
Number of licenses terminated \| item	3
Upfront payment \| Lilly
Collaborative Agreements disclosures
Revenue from contract with customer																			$ 20,000,000
License and milestone fees
Collaborative Agreements disclosures
Revenue from contract with customer		$ 29,551,000	$ 79,000	5,079,000	79,000	1,747,000	672,000	1,321,000	11,540,000	29,580,000	79,000	31,080,000	18,730,000	34,788,000	15,280,000	79,469,000
License and milestone fees \| Lilly
Collaborative Agreements disclosures
Revenue from contract with customer															692,000
Exercise fee \| Lilly
Collaborative Agreements disclosures
Revenue from contract with customer																	$ 2,000,000	$ 2,000,000	$ 2,000,000
Research and development support
Collaborative Agreements disclosures
Revenue from contract with customer				$ 51,000	$ 17,000	218,000	388,000	388,000	383,000	452,000	650,000	902,000	1,478,000	$ 68,000	1,377,000	3,482,000
Clinical materials revenue
Collaborative Agreements disclosures
Revenue from contract with customer						$ 2,170,000	$ 1,427,000	$ 336,000	$ 702,000	$ 1,829,000	$ 1,248,000	$ 599,000	$ 678,000		$ 4,635,000	$ 4,354,000