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Summary of Significant Accounting Policies - Revenue Recognition (Details) - item
1 Months Ended 12 Months Ended
Mar. 31, 2015
Mar. 31, 2013
Dec. 31, 2019
Dec. 31, 2011
Dec. 31, 2010
Minimum          
Summary of Significant Accounting Policies          
Period to earn royalty payments     10 years    
Maximum          
Summary of Significant Accounting Policies          
Period to earn royalty payments     12 years    
Oxford BioTherapeutics Ltd Member          
Summary of Significant Accounting Policies          
Number of single-target licenses     1    
Bayer          
Summary of Significant Accounting Policies          
Number of single-target licenses     1    
Biotest          
Summary of Significant Accounting Policies          
Number of single-target licenses     1    
CytomX          
Summary of Significant Accounting Policies          
Number of single-target licenses     2    
Fusion Pharmaceuticals          
Summary of Significant Accounting Policies          
Number of single-target licenses     1    
Lilly          
Summary of Significant Accounting Policies          
Number of single-target licenses       3  
Novartis          
Summary of Significant Accounting Policies          
Number of single-target licenses   1 5   6
Roche          
Summary of Significant Accounting Policies          
Number of single-target licenses     5    
Sanofi          
Summary of Significant Accounting Policies          
Number of single-target licenses     5    
Takeda          
Summary of Significant Accounting Policies          
Number of single-target licenses     1    
Takeda | Maximum          
Summary of Significant Accounting Policies          
Number of single-target licenses 2        
Debiopharm          
Summary of Significant Accounting Policies          
Number of single-compound licenses     1