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Summary of Significant Accounting Policies - Subsequent Events (Details) - USD ($)
$ in Thousands, shares in Millions
3 Months Ended 12 Months Ended
Feb. 21, 2020
Jan. 27, 2020
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Subsequent Event [Line Items]                                  
Net proceeds generated from public offering                               $ 162,512 $ 101,663
Revenue from contract with customer     $ 44,864 $ 13,281 $ 15,542 $ 8,584 $ 13,416 $ 10,928 $ 9,287 $ 19,815 $ 39,448 $ 8,480 $ 39,020 $ 28,499 $ 82,271 $ 53,446 $ 115,447
Subsequent event                                  
Subsequent Event [Line Items]                                  
Issuance of common stock (in shares)   24.5                              
Net proceeds generated from public offering   $ 97,700                              
Development milestones | Subsequent event | CytomX                                  
Subsequent Event [Line Items]                                  
Revenue from contract with customer $ 3,000