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Agreements - Roche (Details) - USD ($)
$ in Thousands
1 Months Ended 9 Months Ended
May 03, 2019
Jan. 31, 2019
May 31, 2000
Sep. 30, 2019
Sep. 30, 2018
Collaborative Agreements disclosures          
Non-cash royalty revenue related to sale of future royalties       $ 32,102 $ 22,873
Non-cash royalty revenue related to the sale of future royalties       32,102 22,873
Revenue recognized that was previously deferred       237 13,368
Roche          
Collaborative Agreements disclosures          
Period in arrears to receive royalty reports and payments related to sales of Kadcyla     3 months    
Percentage of royalty payments   100.00%      
Roche | Regulatory milestones          
Collaborative Agreements disclosures          
Revenue recognized that was previously deferred $ 5,000        
Roche | Kadcyla          
Collaborative Agreements disclosures          
Non-cash royalty revenue related to sale of future royalties       32,100 22,900
Non-cash royalty revenue related to the sale of future royalties       32,100 $ 22,900
Roche | Kadcyla | Regulatory milestones          
Collaborative Agreements disclosures          
Potential milestone payments       $ 5,000  
OMERS | Kadcyla          
Collaborative Agreements disclosures          
Non-cash royalty revenue related to sale of future royalties   $ 65,200      
Non-cash royalty revenue related to the sale of future royalties   $ 65,200      
Percentage of royalty payments   100.00%